about
The role of methylation in the intrinsic dynamics of B- and Z-DNAMelanoma genome sequencing reveals frequent PREX2 mutationsMutational signatures: the patterns of somatic mutations hidden in cancer genomesDeciphering signatures of mutational processes operative in human cancerAnalysis of next-generation genomic data in cancer: accomplishments and challengesGuanine holes are prominent targets for mutation in cancer and inherited diseaseGenome instability in blood cells of a BRCA1+ breast cancer family.Abasic sites in the transcribed strand of yeast DNA are removed by transcription-coupled nucleotide excision repair.Genomic signatures of germline gene expression.Abrupt onset of mutations in a developmentally regulated gene during terminal differentiation of post-mitotic photoreceptor neurons in mice.Passenger mutations as a marker of clonal cell lineages in emerging neoplasiaMolecular characterization of serous ovarian carcinoma using a multigene next generation sequencing cancer panel approach.CanDrA: cancer-specific driver missense mutation annotation with optimized features.Patterns and processes of somatic mutations in nine major cancers.Lethal mutagenesis: targeting the mutator phenotype in cancer.The somatic autosomal mutation matrix in cancer genomes.Discriminating somatic and germline mutations in tumor DNA samples without matching normals.Transcription as a source of genome instability.Prevalent Accumulation of Non-Optimal Codons through Somatic Mutations in Human Cancers.Single genome retrieval of context-dependent variability in mutation rates for human germlineGenomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencingNext-Generation Sequencing-based genomic profiling of brain metastases of primary ovarian cancer identifies high number of BRCA-mutations.Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability.The integrated landscape of driver genomic alterations in glioblastoma.Whole genome comparison of donor and cloned dogs.Application of second-generation sequencing to cancer genomics.Pre-tumour clones, periodic selection and clonal interference in the origin and progression of gastrointestinal cancer: potential for biomarker development.Direct measurements of human colon crypt stem cell niche genetic fidelity: the role of chance in non-darwinian mutation selection.Contrasting Determinants of Mutation Rates in Germline and Soma.From Mutational Mechanisms in Single Cells to Mutational Patterns in Cancer Genomes.Understanding mutagenesis through delineation of mutational signatures in human cancer.The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury.Germline fitness-based scoring of cancer mutations.Computational approaches for discovery of mutational signatures in cancer.Exome sequencing of primary breast cancers with paired metastatic lesions reveals metastasis-enriched mutations in the A-kinase anchoring protein family (AKAPs).Seeking the driver in tumours with apparent normal molecular profile on comparative genomic hybridization and targeted gene panel sequencing: what is the added value of whole exome sequencing?Comparative analysis of germline and somatic microlesion mutational spectra in 17 human tumor suppressor genes.Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Mutation patterns in cancer genomes.
@ast
Mutation patterns in cancer genomes.
@en
Mutation patterns in cancer genomes.
@nl
type
label
Mutation patterns in cancer genomes.
@ast
Mutation patterns in cancer genomes.
@en
Mutation patterns in cancer genomes.
@nl
prefLabel
Mutation patterns in cancer genomes.
@ast
Mutation patterns in cancer genomes.
@en
Mutation patterns in cancer genomes.
@nl
P2860
P356
P1476
Mutation patterns in cancer genomes.
@en
P2093
Alan F Rubin
Phil Green
P2860
P304
21766-21770
P356
10.1073/PNAS.0912499106
P407
P577
2009-12-07T00:00:00Z