High-throughput screening and small animal models, where are we?
about
Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin ZModeling congenital disease and inborn errors of development in Drosophila melanogasterFishing for Nature's Hits: Establishment of the Zebrafish as a Model for Screening Antidiabetic Natural ProductsThe role of the BK channel in ethanol response behaviors: evidence from model organism and human studiesAlternatives to animal testing: A reviewUnderstanding the genetic and molecular pathogenesis of Friedreich's ataxia through animal and cellular modelsModel organisms in the fight against muscular dystrophy: lessons from drosophila and ZebrafishC. elegans in high-throughput drug discoveryDevelopment and validation of an automated high-throughput system for zebrafish in vivo screeningsMiniaturized embryo array for automated trapping, immobilization and microperfusion of zebrafish embryosA High-Throughput Small Molecule Screen for C. elegans Linker Cell Death InhibitorsZebrafish as a model for acetylcholinesterase-inhibiting organophosphorus agent exposure and oxime reactivationOpen-source approaches for the repurposing of existing or failed candidate drugs: learning from and applying the lessons across diseasesWhole Body Melanoma Transcriptome Response in MedakaHigh-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional modelsCurrent approaches for the discovery of drugs that deter substance and drug abuse.New tools and new biology: recent miniaturized systems for molecular and cellular biology.Multi-endpoint, high-throughput study of nanomaterial toxicity in Caenorhabditis elegans.Live imaging of targeted cell ablation in Xenopus: a new model to study demyelination and repair.Effective heritable gene knockdown in zebrafish using synthetic microRNAs.Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish.COPASutils: an R package for reading, processing, and visualizing data from COPAS large-particle flow cytometers.Rodent Models of Invasive Aspergillosis due to Aspergillus fumigatus: Still a Long Path toward Standardization.A New Ergosterol Analog, a New Bis-Anthraquinone and Anti-Obesity Activity of Anthraquinones from the Marine Sponge-Associated Fungus Talaromyces stipitatus KUFA 0207.High-throughput screening and biosensing with fluorescent C. elegans strains.Whole-animal chemical screen identifies colistin as a new immunomodulator that targets conserved pathways.High-throughput screening for genes that prevent excess DNA replication in human cells and for molecules that inhibit themRNAi screening to identify postembryonic phenotypes in C. elegansA novel zebrafish human tumor xenograft model validated for anti-cancer drug screening.New rationale for large metazoan embryo manipulations on chip-based devices.Anti-cancer drug discovery: update and comparisons in yeast, Drosophila, and zebrafish.Phenotypic screens as a renewed approach for drug discovery.First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass.The use of next-generation sequencing in movement disordersA microfluidic device for whole-animal drug screening using electrophysiological measures in the nematode C. elegans.Development of a vestibular schwannoma xenograft zebrafish model for in vivo antitumor drug screening.In vivo chemical screening for modulators of hematopoiesis and hematological diseasesEvaluating Drosophila p53 as a model system for studying cancer mutationsChemistry and the worm: Caenorhabditis elegans as a platform for integrating chemical and biological research.Wormometry-on-a-chip: Innovative technologies for in situ analysis of small multicellular organisms.
P2860
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P2860
High-throughput screening and small animal models, where are we?
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
High-throughput screening and small animal models, where are we?
@ast
High-throughput screening and small animal models, where are we?
@en
High-throughput screening and small animal models, where are we?
@nl
type
label
High-throughput screening and small animal models, where are we?
@ast
High-throughput screening and small animal models, where are we?
@en
High-throughput screening and small animal models, where are we?
@nl
prefLabel
High-throughput screening and small animal models, where are we?
@ast
High-throughput screening and small animal models, where are we?
@en
High-throughput screening and small animal models, where are we?
@nl
P2860
P1476
High-throughput screening and small animal models, where are we?
@en
P2093
Laurent Ségalat
P2860
P304
P356
10.1111/J.1476-5381.2010.00725.X
P407
P577
2010-05-01T00:00:00Z