Membrane localization of beta-amyloid 1-42 in lysosomes: a possible mechanism for lysosome labilization
about
The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid.Human APOE genotype affects intraneuronal Aβ1-42 accumulation in a lentiviral gene transfer modelDementia of the eye: the role of amyloid beta in retinal degenerationAlzheimer's disease: diverse aspects of mitochondrial malfunctioning.Intra-membrane oligomerization and extra-membrane oligomerization of amyloid-β peptide are competing processes as a result of distinct patterns of motif interplay.Involvement of Intracellular and Mitochondrial Aβ in the Ameliorative Effects of Huperzine A against Oligomeric Aβ42-Induced Injury in Primary Rat Neurons.Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity.Miglustat treatment may reduce cerebrospinal fluid levels of the axonal degeneration marker tau in niemann-pick type C.Differential regulation of amyloid-β endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms.Deficiency of Neuronal p38α MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models through Facilitating Lysosomal Degradation of BACE1.Membrane and surface interactions of Alzheimer's Aβ peptide--insights into the mechanism of cytotoxicity.The role of metallobiology and amyloid-β peptides in Alzheimer's disease.Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease.Pore formation by human stefin B in its native and oligomeric states and the consequent amyloid induced toxicity.A New Perspective of Lysosomal Cation Channel-Dependent Homeostasis in Alzheimer's Disease.Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?Visualization of co-localization in Aβ42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death.Iowa Mutant Apolipoprotein A-I (ApoA-IIowa) Fibrils Target Lysosomes.Aβ internalization by neurons and glia.Depression of Macrophages Modifies Serum Lipid Profile in Hyperlipidemia.Resveratrol reduces amyloid-beta (Aβ₁₋₄₂)-induced paralysis through targeting proteostasis in an Alzheimer model of Caenorhabditis elegans.pH changes the aggregation propensity of amyloid-β without altering the monomer conformation.Using Drosophila Models of Amyloid Toxicity to Study Autophagy in the Pathogenesis of Alzheimer's Disease.
P2860
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P2860
Membrane localization of beta-amyloid 1-42 in lysosomes: a possible mechanism for lysosome labilization
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Membrane localization of beta- ...... nism for lysosome labilization
@ast
Membrane localization of beta- ...... nism for lysosome labilization
@en
Membrane localization of beta- ...... ism for lysosome labilization.
@nl
type
label
Membrane localization of beta- ...... nism for lysosome labilization
@ast
Membrane localization of beta- ...... nism for lysosome labilization
@en
Membrane localization of beta- ...... ism for lysosome labilization.
@nl
prefLabel
Membrane localization of beta- ...... nism for lysosome labilization
@ast
Membrane localization of beta- ...... nism for lysosome labilization
@en
Membrane localization of beta- ...... ism for lysosome labilization.
@nl
P2093
P2860
P356
P1476
Membrane localization of beta- ...... nism for lysosome labilization
@en
P2093
Qiang Zhou
Qing-Hua Zhou
Rui-Qin Liu
Sen-Fang Sui
Shang-Rong Ji
P2860
P304
19986-19996
P356
10.1074/JBC.M109.036798
P407
P50
P577
2010-04-29T00:00:00Z