myc protooncogene linked to retroviral promoter, but not to enhancer, transforms embryo cells.
about
A retroviral promoter is sufficient to convert proto-src to a transforming gene that is distinct from the src gene of Rous sarcoma virus.Avian proto-myc genes promoted by defective or nondefective retroviruses are single-hit transforming genes in primary cells.Dominant transformation by mutated human ras genes in vitro requires more than 100 times higher expression than is observed in cancersThe leucine zipper of c-Myc is required for full inhibition of erythroleukemia differentiation.An avian retrovirus expressing chicken pp59c-myc possesses weak transforming activity distinct from v-myc that may be modulated by adjacent normal cell neighbors.Unmutated proto-src coding region is tumorigenic if expressed from the promoter of Rous sarcoma virus: implications for the gene-mutation hypothesis of cancer.Host range restrictions of oncogenes: myc genes transform avian but not mammalian cells and mht/raf genes transform mammalian but not avian cells.Cancer genes by illegitimate recombination.
P2860
Q33906806-BF01A166-BB48-4E8B-94EF-4D3E7A5A547EQ34310223-648BBC6B-A177-42E1-8A8A-51DAF49EBA7AQ36570897-C0565B4A-FEED-4455-9683-1D93BCF935ABQ36728525-0B4A6346-1158-4C1C-8118-3EF8621D179DQ36828152-6B1D2EFE-5ED0-46AE-A3E8-5483999ADE6BQ37108186-C1B16225-655D-4D5F-8F4B-139AD864B826Q37424780-2C5C03BC-D37D-4DD7-9835-FCC3244B4A26Q38705301-1CA21D2F-C7BA-4D9B-9969-C847161825D2
P2860
myc protooncogene linked to retroviral promoter, but not to enhancer, transforms embryo cells.
description
1988 nî lūn-bûn
@nan
1988 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
name
myc protooncogene linked to re ...... ncer, transforms embryo cells.
@ast
myc protooncogene linked to re ...... ncer, transforms embryo cells.
@en
myc protooncogene linked to re ...... ncer, transforms embryo cells.
@nl
type
label
myc protooncogene linked to re ...... ncer, transforms embryo cells.
@ast
myc protooncogene linked to re ...... ncer, transforms embryo cells.
@en
myc protooncogene linked to re ...... ncer, transforms embryo cells.
@nl
prefLabel
myc protooncogene linked to re ...... ncer, transforms embryo cells.
@ast
myc protooncogene linked to re ...... ncer, transforms embryo cells.
@en
myc protooncogene linked to re ...... ncer, transforms embryo cells.
@nl
P2860
P356
P1476
myc protooncogene linked to re ...... ncer, transforms embryo cells.
@en
P2093
P2860
P304
P356
10.1073/PNAS.85.9.2924
P407
P577
1988-05-01T00:00:00Z