Enzymatic activity is required for the in vivo functions of CARM1. - Wikidata - wikimedia - TriplyDB

Enzymatic activity is required for the in vivo functions of CARM1.

Enzymatic activity is required for the in vivo functions of CARM1.

http://www.wikidata.org/entity/Q33569642

about

CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasis The Role of Protein Arginine Methyltransferases in Inflammatory Responses Arginine methyltransferases as novel therapeutic targets for breast cancer PRMT4 is a novel coactivator of c-Myb-dependent transcription in haematopoietic cell lines Coactivator-Associated Arginine Methyltransferase-1 Function in Alveolar Epithelial Senescence and Elastase-Induced Emphysema Susceptibility Global mapping of CARM1 substrates defines enzyme specificity and substrate recognition.Xenoestrogens regulate the activity of arginine methyltransferases.CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells CARM1 mediates modulation of Sox2.Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.Regulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation.Automethylation of CARM1 allows coupling of transcription and mRNA splicing Histone H3R17me2a mark recruits human RNA polymerase-associated factor 1 complex to activate transcription.Protein arginine methyltransferase 5 (Prmt5) promotes gene expression of peroxisome proliferator-activated receptor γ2 (PPARγ2) and its target genes during adipogenesis.Adipocyte nuclei captured from VAT and SAT Coactivator-associated arginine methyltransferase 1 regulates fetal hematopoiesis and thymocyte development.The BAF chromatin remodelling complex is an epigenetic regulator of lineage specification in the early mouse embryo CARM1 automethylation is controlled at the level of alternative splicing.Overexpression of CARM1 in breast cancer is correlated with poorly characterized clinicopathologic parameters and molecular subtypes.A TR-FRET-based functional assay for screening activators of CARM1 Histone arginine methylation.Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response.The arginine methyltransferase PRMT6 regulates cell proliferation and senescence through transcriptional repression of tumor suppressor genes Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity.Design and synthesis of selective, small molecule inhibitors of coactivator-associated arginine methyltransferase 1 (CARM1).Structural and Functional Impacts of ER Coactivator Sequential Recruitment.Identification and in silico structural analysis of Gallus gallus protein arginine methyltransferase 4 (PRMT4).Regulation of Skeletal Muscle Plasticity by Protein Arginine Methyltransferases and Their Potential Roles in Neuromuscular Disorders.CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity.The arginine methyltransferase CARM1 represses p300•ACT•CREMτ activity and is required for spermiogenesis.CARM1 methylates MED12 to regulate its RNA-binding ability

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P2860

Enzymatic activity is required for the in vivo functions of CARM1.

http://www.wikidata.org/entity/Q33569642

description

2009 nî lūn-bûn

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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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name

Enzymatic activity is required for the in vivo functions of CARM1.

@ast

Enzymatic activity is required for the in vivo functions of CARM1.

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Enzymatic activity is required for the in vivo functions of CARM1.

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type

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Enzymatic activity is required for the in vivo functions of CARM1.

@ast

Enzymatic activity is required for the in vivo functions of CARM1.

@en

Enzymatic activity is required for the in vivo functions of CARM1.

@nl

prefLabel

Enzymatic activity is required for the in vivo functions of CARM1.

@ast

Enzymatic activity is required for the in vivo functions of CARM1.

@en

Enzymatic activity is required for the in vivo functions of CARM1.

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JBC.M109.035865

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Journal of Biological Chemistry

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Enzymatic activity is required for the in vivo functions of CARM1.

@en

P2093

Carla Carter

http://www.w3.org/2001/XMLSchema#string

Daehoon Kim

http://www.w3.org/2001/XMLSchema#string

Donghang Cheng

http://www.w3.org/2001/XMLSchema#string

Ellen Richie

http://www.w3.org/2001/XMLSchema#string

Jaeho Lee

http://www.w3.org/2001/XMLSchema#string

Jia Li

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Mark T Bedford

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P2860

Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status

Fibroblast growth factor receptor 3 is a negative regulator of bone growth

Developmentally essential protein flightless I is a nuclear receptor coactivator with actin binding activity

Crystal structure of the conserved core of protein arginine methyltransferase PRMT3

The structure and oligomerization of the yeast arginine methyltransferase, Hmt1

Structure of the predominant protein arginine methyltransferase PRMT1 and analysis of its binding to substrate peptides

Insights into histone code syntax from structural and biochemical studies of CARM1 methyltransferase

Regulation of transcription by a protein methyltransferase

Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains

Involvement of arginine methyltransferase CARM1 in androgen receptor function and prostate cancer cell viability

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