Enzymatic activity is required for the in vivo functions of CARM1.
about
CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasisThe Role of Protein Arginine Methyltransferases in Inflammatory ResponsesArginine methyltransferases as novel therapeutic targets for breast cancerPRMT4 is a novel coactivator of c-Myb-dependent transcription in haematopoietic cell linesCoactivator-Associated Arginine Methyltransferase-1 Function in Alveolar Epithelial Senescence and Elastase-Induced Emphysema SusceptibilityGlobal mapping of CARM1 substrates defines enzyme specificity and substrate recognition.Xenoestrogens regulate the activity of arginine methyltransferases.CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cellsCARM1 mediates modulation of Sox2.Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.Regulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation.Automethylation of CARM1 allows coupling of transcription and mRNA splicingHistone H3R17me2a mark recruits human RNA polymerase-associated factor 1 complex to activate transcription.Protein arginine methyltransferase 5 (Prmt5) promotes gene expression of peroxisome proliferator-activated receptor γ2 (PPARγ2) and its target genes during adipogenesis.Adipocyte nuclei captured from VAT and SATCoactivator-associated arginine methyltransferase 1 regulates fetal hematopoiesis and thymocyte development.The BAF chromatin remodelling complex is an epigenetic regulator of lineage specification in the early mouse embryoCARM1 automethylation is controlled at the level of alternative splicing.Overexpression of CARM1 in breast cancer is correlated with poorly characterized clinicopathologic parameters and molecular subtypes.A TR-FRET-based functional assay for screening activators of CARM1Histone arginine methylation.Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response.The arginine methyltransferase PRMT6 regulates cell proliferation and senescence through transcriptional repression of tumor suppressor genesNovel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity.Design and synthesis of selective, small molecule inhibitors of coactivator-associated arginine methyltransferase 1 (CARM1).Structural and Functional Impacts of ER Coactivator Sequential Recruitment.Identification and in silico structural analysis of Gallus gallus protein arginine methyltransferase 4 (PRMT4).Regulation of Skeletal Muscle Plasticity by Protein Arginine Methyltransferases and Their Potential Roles in Neuromuscular Disorders.CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity.The arginine methyltransferase CARM1 represses p300•ACT•CREMτ activity and is required for spermiogenesis.CARM1 methylates MED12 to regulate its RNA-binding ability
P2860
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P2860
Enzymatic activity is required for the in vivo functions of CARM1.
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
Enzymatic activity is required for the in vivo functions of CARM1.
@ast
Enzymatic activity is required for the in vivo functions of CARM1.
@en
Enzymatic activity is required for the in vivo functions of CARM1.
@nl
type
label
Enzymatic activity is required for the in vivo functions of CARM1.
@ast
Enzymatic activity is required for the in vivo functions of CARM1.
@en
Enzymatic activity is required for the in vivo functions of CARM1.
@nl
prefLabel
Enzymatic activity is required for the in vivo functions of CARM1.
@ast
Enzymatic activity is required for the in vivo functions of CARM1.
@en
Enzymatic activity is required for the in vivo functions of CARM1.
@nl
P2093
P2860
P356
P1476
Enzymatic activity is required for the in vivo functions of CARM1.
@en
P2093
Carla Carter
Daehoon Kim
Donghang Cheng
Ellen Richie
Mark T Bedford
P2860
P304
P356
10.1074/JBC.M109.035865
P407
P577
2009-11-05T00:00:00Z