Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation.
about
The contribution of mouse models to the understanding of constitutional thrombocytopeniaGenetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell FunctionFrom cytopenia to leukemia: the role of Gfi1 and Gfi1b in blood formationWhole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis.Inherited thrombocytopenia: novel insights into megakaryocyte maturation, proplatelet formation and platelet lifespan.Functional characterization of a novel GFI1B mutation causing congenital macrothrombocytopenia.Gfi1b controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes.Mouse RUNX1C regulates premegakaryocytic/erythroid output and maintains survival of megakaryocyte progenitors.RUNX1B Expression Is Highly Heterogeneous and Distinguishes Megakaryocytic and Erythroid Lineage Fate in Adult Mouse Hematopoiesis.Cooperative Stimulation of Megakaryocytic Differentiation by Gfi1b Gene Targets Kindlin3 and Talin1Control of developmentally primed erythroid genes by combinatorial co-repressor actionsReciprocal regulation of alternative lineages by Rgs18 and its transcriptional repressor Gfi1bHistone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis.Evolving insights into the synergy between erythropoietin and thrombopoietin and the bipotent erythroid/megakaryocytic progenitor cell.Should any genetic defect affecting α-granules in platelets be classified as gray platelet syndrome?Transcription Factor GFI1B in Health and Disease.Platelets as autonomous drones for hemostatic and immune surveillance.Principles of Amnis Imaging Flow Cytometry.The Corepressor Rcor1 Is Essential for Normal Myeloerythroid Lineage Differentiation.CBFβ-SMMHC creates aberrant megakaryocyte-erythroid progenitors prone to leukemia initiation in mice.Recessive grey platelet-like syndrome with unaffected erythropoiesis in the absence of the splice isoform GFI1B-p37.Thrombocytopenia and CD34 expression is decoupled from α-granule deficiency with mutation of the first growth factor-independent 1B zinc finger.A novel GFI1B mutation at the first zinc finger domain causes congenital macrothrombocytopenia.Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome.Combined alpha-delta platelet storage pool deficiency is associated with mutations in GFI1B.EVI1 overexpression reprograms hematopoiesis via upregulation of Spi1 transcription
P2860
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P2860
Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation.
description
2014 nî lūn-bûn
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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2014 թվականի ապրիլին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年學術文章
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name
Distinct, strict requirements ...... cell and platelet generation.
@ast
Distinct, strict requirements ...... cell and platelet generation.
@en
Distinct, strict requirements ...... cell and platelet generation.
@nl
type
label
Distinct, strict requirements ...... cell and platelet generation.
@ast
Distinct, strict requirements ...... cell and platelet generation.
@en
Distinct, strict requirements ...... cell and platelet generation.
@nl
prefLabel
Distinct, strict requirements ...... cell and platelet generation.
@ast
Distinct, strict requirements ...... cell and platelet generation.
@en
Distinct, strict requirements ...... cell and platelet generation.
@nl
P2093
P2860
P356
P1476
Distinct, strict requirements ...... cell and platelet generation.
@en
P2093
Anna-Sophie Behlich
Arnaud Amzallag
Daniel J Kramer
Frederic I Preffer
Hanno Hock
Jinzhong Qin
Scott Mordecai
Sridhar Ramaswamy
Stuart H Orkin
P2860
P304
P356
10.1084/JEM.20131065
P407
P577
2014-04-07T00:00:00Z