Variable region framework differences result in decreased or increased affinity of variant anti-digoxin antibodies.
about
Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes.Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coliParacrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodiesDetermination of antibody affinity.Protein evolution on rugged landscapes.Anti-digoxin Fab variants generated by phage display.Modulation of antibody affinity by a non-contact residue.Contribution of a single heavy chain residue to specificity of an anti-digoxin monoclonal antibody.Mutational analysis of an autoantibody: differential binding and pathogenicity.Influence of the NH2-terminal amino acid of the T cell receptor alpha chain on major histocompatibility complex (MHC) class II + peptide recognition.Antibody engineering toward high-sensitivity high-throughput immunosensing of small molecules.Site-specific mutagenesis of a recombinant anti-single-stranded DNA Fab. Role of heavy chain complementarity-determining region 3 residues in antigen interaction.Efficient amplification and direct sequencing of mouse variable regions from any immunoglobulin gene family.Characterization of two human anti-DNA antibodies bearing the pathogenic idiotype 8.12.Repertoire shift occurs during the memory maintenance phase of the immune responses and is not affinity-driven.
P2860
Q31131763-F6A86ECD-9984-4ABB-A939-E90DC8294C0AQ33638891-EC1F61F7-7840-480A-9C81-4BD6FB48C00AQ33843281-CC757D62-FAD8-49AE-A2D0-0B4EBA266B84Q33993598-CEA238A2-1D6D-4BAD-9BD0-622BDB32EAD7Q34296709-55C61B0F-2187-47D7-BC66-DD959D0A5FC6Q34566178-CDB13EB8-6147-4535-B875-6526C8C557C4Q36277890-DAF92604-E5CC-42D4-9596-9AC96DF78BE6Q36278518-AD1F62C4-EB6D-4164-A732-125047211B97Q36363653-B71739AA-7047-43E7-AB5A-93AA885AC6A2Q36377306-622F61FA-1FB8-4414-A7B8-D8E375647809Q37820247-5BECCE7D-2A8A-439C-A8FC-C6EF0D09EFE4Q38342345-8D2DA848-D1F4-4686-8B73-535DB30D546CQ40945142-743D5620-33B5-4145-9192-C18BA41206B3Q48142878-253D58D5-1657-4818-B806-93758DDF9BC3Q52035304-87D2421C-E490-4429-A42A-CCBD6769596A
P2860
Variable region framework differences result in decreased or increased affinity of variant anti-digoxin antibodies.
description
1988 nî lūn-bûn
@nan
1988 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Variable region framework diff ...... riant anti-digoxin antibodies.
@ast
Variable region framework diff ...... riant anti-digoxin antibodies.
@en
Variable region framework diff ...... riant anti-digoxin antibodies.
@nl
type
label
Variable region framework diff ...... riant anti-digoxin antibodies.
@ast
Variable region framework diff ...... riant anti-digoxin antibodies.
@en
Variable region framework diff ...... riant anti-digoxin antibodies.
@nl
prefLabel
Variable region framework diff ...... riant anti-digoxin antibodies.
@ast
Variable region framework diff ...... riant anti-digoxin antibodies.
@en
Variable region framework diff ...... riant anti-digoxin antibodies.
@nl
P2093
P2860
P356
P1476
Variable region framework diff ...... riant anti-digoxin antibodies.
@en
P2093
L A Herzenberg
L L Peterson
M Mudgett-Hunter
M N Margolies
P2860
P304
P356
10.1073/PNAS.85.9.3080
P407
P577
1988-05-01T00:00:00Z