Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.
about
Small molecule tools for functional interrogation of protein tyrosine phosphatasesSubstrate Deconstruction and the Nonadditivity of Enzyme RecognitionComprehensive survey of chemical libraries for drug discovery and chemical biology: 2009.Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase.Mycobacterium tuberculosis Serine/Threonine Protein Kinases.Identification of multiple structurally distinct, nonpeptidic small molecule inhibitors of protein arginine deiminase 3 using a substrate-based fragment methodNovel 1,4-substituted-1,2,3-triazoles as antitubercular agents.Mycobacterial Protein Tyrosine Phosphatases A and B Inhibitors Augment the Bactericidal Activity of the Standard Anti-tuberculosis RegimenNew strategies in fighting TB: targeting Mycobacterium tuberculosis-secreted phosphatases MptpA & MptpB.How to cope with the quest for new antibiotics.Tuberculosis drugs: new candidates and how to find more.Elimination of intracellularly residing Mycobacterium tuberculosis through targeting of host and bacterial signaling mechanisms.Substrate Activity Screening (SAS) and Related Approaches in Medicinal Chemistry.Druggability analysis and classification of protein tyrosine phosphatase active sites.The antibiotic Furvina® targets the P-site of 30S ribosomal subunits and inhibits translation initiation displaying start codon bias.Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases.Dynamic substrate enhancement for the identification of specific, second-site-binding fragments targeting a set of protein tyrosine phosphatases.Spirochromone-chalcone conjugates as antitubercular agents: synthesis, bio evaluation and molecular modeling studies
P2860
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P2860
Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Fragment-based discovery of se ...... ein tyrosine phosphatase PtpA.
@ast
Fragment-based discovery of se ...... ein tyrosine phosphatase PtpA.
@en
Fragment-based discovery of se ...... ein tyrosine phosphatase PtpA.
@nl
type
label
Fragment-based discovery of se ...... ein tyrosine phosphatase PtpA.
@ast
Fragment-based discovery of se ...... ein tyrosine phosphatase PtpA.
@en
Fragment-based discovery of se ...... ein tyrosine phosphatase PtpA.
@nl
prefLabel
Fragment-based discovery of se ...... ein tyrosine phosphatase PtpA.
@ast
Fragment-based discovery of se ...... ein tyrosine phosphatase PtpA.
@en
Fragment-based discovery of se ...... ein tyrosine phosphatase PtpA.
@nl
P2093
P2860
P1476
Fragment-based discovery of se ...... ein tyrosine phosphatase PtpA.
@en
P2093
Christoph Grundner
Jonathan A Ellman
Jun Takeuchi
Katherine A Rawls
P Therese Lang
Shinichi Imamura
Tyler D Baguley
P2860
P304
P356
10.1016/J.BMCL.2009.10.090
P407
P577
2009-10-25T00:00:00Z