Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression.
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The interactions of GW182 proteins with PABP and deadenylases are required for both translational repression and degradation of miRNA targetsTwo PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencingGW182 proteins cause PABP dissociation from silenced miRNA targets in the absence of deadenylationNuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPsHuman SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter geneTiny giants of gene regulation: experimental strategies for microRNA functional studiesThe role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnoverp38α mitogen-activated protein kinase depletion and repression of signal transduction to translation machinery by miR-124 and -128 in neuronsEdc3 function in yeast and mammals is modulated by interaction with NAD-related compoundsCis-acting polymorphisms affect complex traits through modifications of microRNA regulation pathways.MicroRNAs in inner ear biology and pathogenesis.Computational methods to identify miRNA targets.The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.Poly(A) binding proteins: are they all created equal?The complexity of miRNA-mediated repressionmiRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock.The type II poly(A)-binding protein PABP-2 genetically interacts with the let-7 miRNA and elicits heterochronic phenotypes in Caenorhabditis elegans.Stability of a long noncoding viral RNA depends on a 9-nt core element at the RNA 5' end to interact with viral ORF57 and cellular PABPC1.Translational inhibition by deadenylation-independent mechanisms is central to microRNA-mediated silencing in zebrafish.Attenuation of neurovirulence, biodistribution, and shedding of a poliovirus:rhinovirus chimera after intrathalamic inoculation in Macaca fascicularis.ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expressionImproved dual AAV vectors with reduced expression of truncated proteins are safe and effective in the retina of a mouse model of Stargardt disease.A molecular link between miRISCs and deadenylases provides new insight into the mechanism of gene silencing by microRNAs.Interplay between polyadenylate-binding protein 1 and Kaposi's sarcoma-associated herpesvirus ORF57 in accumulation of polyadenylated nuclear RNA, a viral long noncoding RNA.A miRNA-responsive cell-free translation system facilitates isolation of hepatitis C virus miRNP complexes.miRNAs and HIV: unforeseen determinants of host-pathogen interaction.MicroRNAs and the immune response to respiratory virus infections.MicroRNA-mediated gene silencing: are we close to a unifying model?MicroRNAs recruit eIF4E2 to repress translation of target mRNAs.The decapping activator HPat a novel factor co-purifying with GW182 from Drosophila cells.RNA duplexes in transcriptional regulation.microRNAs stimulate translation initiation mediated by HCV-like IRESes.miRNA repression of translation in vitro takes place during 43S ribosomal scanning.IRES-Dependent Translational Control during Virus-Induced Endoplasmic Reticulum Stress and ApoptosisHuman DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1.A role for eIF4AII in microRNA-mediated mRNA silencing.Human La binds mRNAs through contacts to the poly(A) tail.Express: A database of transcriptome profiles encompassing known and novel transcripts across multiple development stages in eye tissues.
P2860
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P2860
Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression.
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Poly(A)-binding protein modula ...... ent miRNA-mediated repression.
@ast
Poly(A)-binding protein modula ...... ent miRNA-mediated repression.
@en
type
label
Poly(A)-binding protein modula ...... ent miRNA-mediated repression.
@ast
Poly(A)-binding protein modula ...... ent miRNA-mediated repression.
@en
prefLabel
Poly(A)-binding protein modula ...... ent miRNA-mediated repression.
@ast
Poly(A)-binding protein modula ...... ent miRNA-mediated repression.
@en
P2093
P2860
P356
P1433
P1476
Poly(A)-binding protein modula ...... ent miRNA-mediated repression.
@en
P2093
Matthias Gromeier
Robert W Walters
Shelton S Bradrick
P2860
P304
P356
10.1261/RNA.1795410
P407
P577
2009-11-24T00:00:00Z