Pin1 promotes transforming growth factor-beta-induced migration and invasion. - Wikidata - wikimedia - TriplyDB

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

http://www.wikidata.org/entity/Q33581891

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Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β Pathways A Smad action turnover switch operated by WW domain readers of a phosphoserine code Understanding the role of PIN1 in hepatocellular carcinoma Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis Redox proteomics in selected neurodegenerative disorders: from its infancy to future applications.Differential regulation of Smad3 and of the type II transforming growth factor-β receptor in mitosis: implications for signaling Prediction of gastric cancer metastasis through urinary metabolomic investigation using GC/MS.Curcumin and emodin down-regulate TGF-β signaling pathway in human cervical cancer cells.Pin1 null mice exhibit low bone mass and attenuation of BMP signaling Constitutive Smad linker phosphorylation in melanoma: a mechanism of resistance to transforming growth factor-β-mediated growth inhibition.Pin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease.Smad phosphoisoform signaling specificity: the right place at the right time Human leucine zipper protein sLZIP induces migration and invasion of cervical cancer cells via expression of matrix metalloproteinase-9.Smad phosphoisoform signals in acute and chronic liver injury: similarities and differences between epithelial and mesenchymal cells.Pin1 protein regulates Smad protein signaling and pulmonary fibrosis.Phospho-specific Smad3 signaling: impact on breast oncogenesis.Inhibition of CDK-mediated phosphorylation of Smad3 results in decreased oncogenesis in triple negative breast cancer cells.Cell signals influencing hepatic fibrosis Pin1 facilitates NF-κB activation and promotes tumour progression in human hepatocellular carcinoma.Expression of peptidyl-prolyl isomerase PIN1 and its role in the pathogenesis of extrahepatic cholangiocarcinoma.Role of Smads in TGFβ signaling.Differential Regulation of TGF-β/Smad Signaling in Hepatic Stellate Cells between Acute and Chronic Liver Injuries.Post-translational regulation of TGF-β receptor and Smad signaling.Peptidyl-prolyl isomerases: functionality and potential therapeutic targets in cardiovascular disease.Inhibition of CDK-mediated Smad3 phosphorylation reduces the Pin1-Smad3 interaction and aggressiveness of triple negative breast cancer cells.Pin1, the Master Orchestrator of Bone Cell Differentiation.TGF-β Signaling from Receptors to Smads.bHLH proteins involved in Drosophila neurogenesis are mutually regulated at the level of stability Neighboring phosphoSer-Pro motifs in the undefined domain of IRAK1 impart bivalent advantage for Pin1 binding.Regulation of S100A2 expression by TGF-β-induced MEK/ERK signalling and its role in cell migration/invasion.Hexim-1 modulates androgen receptor and the TGF-β signaling during the progression of prostate cancer.Identification of phosphorylated proteins involved in the oncogenesis of prostate cancer via Pin1-proteomic analysis.Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites.Blood-testis barrier integrity depends on Pin1 expression in Sertoli cells.Oligodendrocyte transcription factor 1 (Olig1) is a Smad cofactor involved in cell motility induced by transforming growth factor-β.Phase II neoadjuvant clinical trial of carboplatin and eribulin in women with triple negative early-stage breast cancer (NCT01372579).Role of the CYP3A4-mediated 11,12-epoxyeicosatrienoic acid pathway in the development of tamoxifen-resistant breast cancer Pin1 plays a critical role as a molecular switch in canonical BMP signaling.Synergistic effect of eribulin and CDK inhibition for the treatment of triple negative breast cancer.

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P2860

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

http://www.wikidata.org/entity/Q33581891

description

2009 nî lūn-bûn

@nan

2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

@ast

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

@en

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

@nl

type

label

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

@ast

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

@en

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

@nl

prefLabel

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

@ast

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

@en

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

@nl

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JBC.M109.063826

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Journal of Biological Chemistry

P1476

Pin1 promotes transforming growth factor-beta-induced migration and invasion.

@en

P2093

Akihide Ryo

http://www.w3.org/2001/XMLSchema#string

Chen-Yu Lai

http://www.w3.org/2001/XMLSchema#string

Dongming He

http://www.w3.org/2001/XMLSchema#string

Fang Liu

http://www.w3.org/2001/XMLSchema#string

Guannan Wang

http://www.w3.org/2001/XMLSchema#string

Isao Matsuura

http://www.w3.org/2001/XMLSchema#string

Keng-Nan Chiang

http://www.w3.org/2001/XMLSchema#string

Kunping Lu

http://www.w3.org/2001/XMLSchema#string

Romila Ramkumar

http://www.w3.org/2001/XMLSchema#string

P2860

Transforming growth factor beta -inducible independent binding of SMAD to the Smad7 promoter

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel

Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

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1754-1764

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scholarly article

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10.1074/JBC.M109.063826

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3

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285

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Takafumi Uchida

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2009-11-17T00:00:00Z

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19920136

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2804333

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