Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate.
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Synthesis and preliminary cytotoxicity study of a cephalosporin-CC-1065 analogue prodrugAn enzymatically activated fluorescence probe for targeted tumor imaging.Selective delivery of therapeutic agents for the diagnosis and treatment of cancer.Recent trends in targeted anticancer prodrug and conjugate design.Toward antibody-directed "abzyme" prodrug therapy, ADAPT: carbamate prodrug activation by a catalytic antibody and its in vitro application to human tumor cell killing.Targeted prodrug design to optimize drug delivery.Antibody-directed enzyme prodrug therapy (ADEPT) for cancer.Differential permeability and quantitative MR imaging of a human lung carcinoma brain xenograft in the nude rat.Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood.A monoclonal antibody-beta-glucuronidase conjugate as activator of the prodrug epirubicin-glucuronide for specific treatment of cancer.Anti-tumour effects of an antibody-carboxypeptidase G2 conjugate in combination with phenol mustard prodrugsIn vivo activity in a catalytic antibody-prodrug system: Antibody catalyzed etoposide prodrug activation for selective chemotherapyTheranostic etoposide phosphate/indium nanoparticles for cancer therapy and imaging.Drug targeting with monoclonal antibodies. A review.Haemodynamic and transport barriers to the treatment of solid tumours.Development of antibodies for cancer therapy.Bystander killing of tumour cells by antibody-targeted enzymatic activation of a glucuronide prodrugPharmacokinetic analysis of the microscopic distribution of enzyme-conjugated antibodies and prodrugs: comparison with experimental dataAntibody-enzyme fusion proteins for cancer therapy.Challenges in developing bioanalytical assays for characterization of antibody-drug conjugates.A fully human anti-Ep-CAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug.The First Bagshawe lecture. Towards generating cytotoxic agents at cancer sitesTranslating antibody directed enzyme prodrug therapy (ADEPT) and prospects for combination.ADEPT and related concepts.Review: advances in monoclonal antibody tumour targeting.Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody beta-glucuronidase conjugate.A new application for liposomes in cancer therapy. Immunoliposomes bearing enzymes (immuno-enzymosomes) for site-specific activation of prodrugs.Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis.Conversion of the prodrug etoposide phosphate to etoposide in gastric juice and bile.Plasma clearance of an antibody--enzyme conjugate in ADEPT by monoclonal anti-enzyme: its effect on prodrug activation in vivoGeneration of bispecific monoclonal antibodies for two phase radioimmunotherapy.Inactivation and clearance of an anti-CEA carboxypeptidase G2 conjugate in blood after localisation in a xenograft modelTargeting enzymes for cancer therapy: old enzymes in new roles.Strategies in antibody therapy of cancer.Potentiation of antitumor immunity by antibody-directed enzyme prodrug therapy.Alternative splicing as a novel of means of regulating the expression of therapeutic genes.Targeting enzymes to cancers--new developments.A universal antibody-derived targeting agent.Human immune response to monoclonal antibody-enzyme conjugates in ADEPT pilot clinical trial
P2860
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P2860
Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate.
description
1988 nî lūn-bûn
@nan
1988 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Anti-tumor effects of antibody ...... tion with etoposide phosphate.
@ast
Anti-tumor effects of antibody ...... tion with etoposide phosphate.
@en
Anti-tumor effects of antibody ...... tion with etoposide phosphate.
@nl
type
label
Anti-tumor effects of antibody ...... tion with etoposide phosphate.
@ast
Anti-tumor effects of antibody ...... tion with etoposide phosphate.
@en
Anti-tumor effects of antibody ...... tion with etoposide phosphate.
@nl
prefLabel
Anti-tumor effects of antibody ...... tion with etoposide phosphate.
@ast
Anti-tumor effects of antibody ...... tion with etoposide phosphate.
@en
Anti-tumor effects of antibody ...... tion with etoposide phosphate.
@nl
P2093
P2860
P356
P1476
Anti-tumor effects of antibody ...... tion with etoposide phosphate.
@en
P2093
Hellström I
Hellström KE
Hirschberg DL
Saulnier MG
Schreiber GJ
P2860
P304
P356
10.1073/PNAS.85.13.4842
P407
P577
1988-07-01T00:00:00Z