The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
about
Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1)Hyaluronan Synthase: The Mechanism of Initiation at the Reducing End and a Pendulum Model for Polysaccharide Translocation to the Cell ExteriorInsights into the structure and function of membrane-integrated processive glycosyltransferases.Regulated Hyaluronan Synthesis by Vascular CellsCollagen VI and hyaluronan: the common role in breast cancerHyaluronan - a functional and structural sweet spot in the tissue microenvironmentTissue distribution and subcellular localization of hyaluronan synthase isoenzymesCRISPR/Cas9 knockout of HAS2 in rat chondrosarcoma chondrocytes demonstrates the requirement of hyaluronan for aggrecan retention.Hyaluronan synthase 2 protects skin fibroblasts against apoptosis induced by environmental stress.A novel mutation of Hyaluronan synthase 2 gene in Chinese children with ventricular septal defect.Hyaluronan-CD44 interactions as potential targets for cancer therapy.Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3Estradiol protects dermal hyaluronan/versican matrix during photoaging by release of epidermal growth factor from keratinocytes.Hyaluronan Synthase 3 Null Mice Exhibit Decreased Intestinal Inflammation and Tissue Damage in the DSS-Induced Colitis Model.The deubiquitinating enzymes USP4 and USP17 target hyaluronan synthase 2 and differentially affect its function.4-Methylumbelliferone Diminishes Catabolically Activated Articular Chondrocytes and Cartilage Explants via a Mechanism Independent of Hyaluronan Inhibition.Oxidized low density lipoprotein (LDL) affects hyaluronan synthesis in human aortic smooth muscle cells.Glycosaminoglycans: key players in cancer cell biology and treatment.Deregulation of hyaluronan synthesis, degradation and binding promotes breast cancer.More than just a filler - the role of hyaluronan for skin homeostasis.Epigenetics in extracellular matrix remodeling and hyaluronan metabolism.Hyaluronan synthase 1: a mysterious enzyme with unexpected functionsRab10-mediated endocytosis of the hyaluronan synthase HAS3 regulates hyaluronan synthesis and cell adhesion to collagen.Biology and biotechnology of hyaluronan.Human Keratinocytes Respond to Extracellular UTP by Induction of Hyaluronan Synthase 2 Expression and Increased Hyaluronan Synthesis.Drug-Mediated Regulation of Glycosaminoglycan Biosynthesis.Role of UDP-N-acetylglucosamine (GlcNAc) and O-GlcNAcylation of hyaluronan synthase 2 in the control of chondroitin sulfate and hyaluronan synthesis.The control and importance of hyaluronan synthase expression in palatogenesis.Hyaluronan synthesis is inhibited by adenosine monophosphate-activated protein kinase through the regulation of HAS2 activity in human aortic smooth muscle cells.Chain gangs: new aspects of hyaluronan metabolism.Efficient TGFβ-induced epithelial-mesenchymal transition depends on hyaluronan synthase HAS2.Divergent Temporal Expression of Hyaluronan Metabolizing Enzymes and Receptors with Craniotomy vs. Controlled-Cortical Impact Injury in Rat Brain: A Pilot StudyAccumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment.Hyaluronan synthases (HAS1-3) in stromal and malignant cells correlate with breast cancer grade and predict patient survival.A Trickster in Disguise: Hyaluronan's Ambivalent Roles in the Matrix.Hyaluronan synthase assembles hyaluronan on a [GlcNAc(β1,4)]n-GlcNAc(α1→)UDP primer and hyaluronan retains this residual chitin oligomer as a cap at the nonreducing end.
P2860
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P2860
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
@ast
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
@en
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
@nl
type
label
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
@ast
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
@en
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
@nl
prefLabel
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
@ast
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
@en
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
@nl
P2093
P2860
P356
P1476
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
@en
P2093
Aino Ruusala
Carl-Henrik Heldin
Eugenia Karousou
Hidetoshi Yamashita
Masaru Kamiryo
Paraskevi Heldin
Spyros S Skandalis
Trias Asteriou
Ulf Hellman
P2860
P304
23647-23654
P356
10.1074/JBC.M110.127050
P407
P577
2010-05-27T00:00:00Z