Quantification assays for total and polyglutamine-expanded huntingtin proteins.

Quantification assays for total and polyglutamine-expanded huntingtin proteins.

Item
http://www.wikidata.org/entity/Q33590805
Allele-Selective Suppression of Mutant Huntingtin in Primary Human Blood Cells.Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's diseaseQuantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients.Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppressionChallenges of Huntington's disease and quest for therapeutic biomarkers.Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.Polyglutamine expansion affects huntingtin conformation in multiple Huntington's disease models.Elimination of huntingtin in the adult mouse leads to progressive behavioral deficits, bilateral thalamic calcification, and altered brain iron homeostasis.The Generation of Mouse and Human Huntington Disease iPS Cells Suitable for In vitro Studies on Huntingtin FunctionAggregation landscapes of Huntingtin exon 1 protein fragments and the critical repeat length for the onset of Huntington's disease.Novel allele-specific quantification methods reveal no effects of adult onset CAG repeats on HTT mRNA and protein levels.Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation.Monomeric Huntingtin Exon 1 Has Similar Overall Structural Features for Wild-Type and Pathological Polyglutamine Lengths.Quantification of huntingtin protein species in Huntington's disease patient leukocytes using optimised electrochemiluminescence immunoassays.Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex.Validation of Ultrasensitive Mutant Huntingtin Detection in Human Cerebrospinal Fluid by Single Molecule Counting Immunoassay.Quantification of Total and Mutant Huntingtin Protein Levels in Biospecimens Using a Novel alphaLISA Assay
P2860

Quantification assays for total and polyglutamine-expanded huntingtin proteins.

Item
http://www.wikidata.org/entity/Q33590805
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
name
Quantification assays for total and polyglutamine-expanded huntingtin proteins.
@ast
Quantification assays for total and polyglutamine-expanded huntingtin proteins.
@en
type
label
Quantification assays for total and polyglutamine-expanded huntingtin proteins.
@ast
Quantification assays for total and polyglutamine-expanded huntingtin proteins.
@en
prefLabel
Quantification assays for total and polyglutamine-expanded huntingtin proteins.
@ast
Quantification assays for total and polyglutamine-expanded huntingtin proteins.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Quantification assays for total and polyglutamine-expanded huntingtin proteins.
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0096854
P407
P433
P478
P50
P577
P5875
P698
P932