Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus. - Wikidata - wikimedia - TriplyDB

Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus.

Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus.

http://www.wikidata.org/entity/Q33591655

about

Inflammatory cytokines in systemic lupus erythematosus FoxP3+ regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availability.IL-2 protects lupus-prone mice from multiple end-organ damage by limiting CD4-CD8- IL-17-producing T cells mTOR signaling: a central pathway to pathogenesis in systemic lupus erythematosus?SM934 treated lupus-prone NZB × NZW F1 mice by enhancing macrophage interleukin-10 production and suppressing pathogenic T cell development.Compensatory T-cell regulation in unaffected relatives of SLE patients, and opposite IL-2/CD25-mediated effects suggested by coreferentiality modeling.Longevity of SLE-prone mice increased by dietary 2-mercaptoethanol via a mechanism imprinted within the first 28 days of life.Beyond regulatory T cells: the potential role for IL-2 to deplete T-follicular helper cells and treat autoimmune diseases.CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis CD4+FOXP3+ T regulatory cells in human autoimmunity: more than a numbers game Regulatory T cell-deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease.Pre-B cell leukemia homeobox 1 is associated with lupus susceptibility in mice and humans.The XX sex chromosome complement in mice is associated with increased spontaneous lupus compared with XY.Regulatory T Cell Responses to High-Dose Methylprednisolone in Active Systemic Lupus Erythematosus Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation.CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice.Low-dose interleukin-2 therapy restores regulatory T cell homeostasis in patients with chronic graft-versus-host disease.Circulating level of regulatory T cells in rheumatic heart disease: An observational study.Engagement of SLAMF3 enhances CD4+ T-cell sensitivity to IL-2 and favors regulatory T-cell polarization in systemic lupus erythematosus Glucocorticoid receptor in T cells mediates protection from autoimmunity in pregnancy.Treatment of systemic lupus erythematosus: new advances in targeted therapy.Interleukin 2 in the pathogenesis and therapy of type 1 diabetes.Regulatory T cells in systemic lupus erythematosus.Mapping urinary chemokines in human lupus nephritis: Potentially redundant pathways recruit CD4+ and CD8+ T cells and macrophages.T cells and IL-17 in lupus nephritis.Restoring regulation - IL-2 therapy in systemic lupus erythematosus.Low-Dose IL-2 in the Treatment of Lupus.Foxp3, Regulatory T Cell, and Autoimmune Diseases.T cells and autoimmune kidney disease.Dysregulated Lymphoid Cell Populations in Mouse Models of Systemic Lupus Erythematosus.Interleukin-2 treatment reverses effects of cAMP-responsive element modulator α-over-expressing T cells in autoimmune-prone mice.Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus.Lupus at the molecular level Natural Treg and role of IL-2 in lupus.The Role of the Transcription Factor Ets1 in Lupus and Other Autoimmune Diseases.Downregulation of miR-200a-3p, Targeting CtBP2 Complex, Is Involved in the Hypoproduction of IL-2 in Systemic Lupus Erythematosus-Derived T Cells.[Pathogenesis of systemic lupus erythematosus].Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus.[Regulatory T cells and rheumatic diseases].Rapid induction of clinical remission by low-dose interleukin-2 in a patient with refractory SLE.

P2860

Q26823647-49EDF48B-AC02-4EB7-8D4F-789DBB60DA71 Q33580878-00A6586F-0817-41A2-AF1F-9457D08716E7 Q34053939-52E11154-A5B4-4661-878C-4239145948B6 Q34107250-20A74AC7-E5C7-46AA-8D08-AF9194569AFA Q34184574-16A1C851-C294-43B9-93A0-84485C652284 Q34221885-7E945906-B4A1-4519-B04E-4F1760502F89 Q34775743-3621827C-6BF1-459C-BDF6-36E3B19E8636 Q34901832-6BBC33A2-2152-44FC-9330-A496D7F9DB23 Q34937677-647DEE18-46A4-433F-9B0D-BB4717242D61 Q35178495-E4A499E4-EAB6-4BE8-B530-2733FBD46F97 Q35344378-C0C5259D-FAE5-437B-BB3A-3306703588B5 Q35658918-3B86EF2B-408A-4F88-B13F-70CC944FD865 Q35674459-BC1A4663-3DA5-4205-9973-E9B954BBBEC1 Q35858597-5A610132-10D2-4347-91AD-1862A8BAF880 Q35991917-44DF4D60-7659-4EF2-9818-CE6919269444 Q36903043-1A139074-F516-4353-AE00-C3157C2DC758 Q36940174-7EC98A57-7C1C-440E-822B-5E19C0479494 Q37014560-2A3054B2-CCEE-4FCD-8CFE-4874E4E9AC8C Q37200094-6EEB9B0C-0BE3-4862-A05B-29E297F0327A Q37589953-C63651DE-A0A1-4CCB-96B7-475498B524D3 Q37974990-AE8D5897-1BC3-413A-9614-4011DBFCC612 Q38262670-9679A09E-4104-4E82-9EB9-5117446E8EA7 Q38265968-9914195F-375D-48B2-861E-10A35B8C0628 Q38810115-D8F37FF7-E2F0-4CBC-B4CA-E749FB21A0EE Q38816316-51D8EC1E-7D16-40D3-8889-65C4EF225AF3 Q38860839-927B83AC-8723-4EF1-9C02-AA426B5E8A52 Q38979253-B2675E3B-5DF9-4E6A-A8F9-7A867A276E50 Q39018591-29C0E860-9FB5-4FFA-B57A-C26A15AB9AF8 Q39175811-71E569D4-3FE8-4209-979D-DB892396E19E Q39303557-5895D1D0-7F08-437F-95D5-461695C46681 Q41147908-92AA3988-75EC-4826-9A28-57F46FF7679A Q42518281-045CD163-14EF-4550-9D08-80175A667288 Q42772178-D8865D05-AAAE-48CA-85B5-953A4B77B69D Q46002068-BACD8E62-B9C1-483B-94C6-B64B8976562C Q47134266-2B330CF7-4523-4A85-9AC1-12169D4A658D Q48238048-E22B8584-73FE-4808-9D78-62AD87367A76 Q50742675-6BA4CB1D-15F4-4397-A00A-26C3BDD32A3A Q50940528-B5C83502-E52C-45AD-91A3-01F49181866C Q52869751-EBFE6D03-E4D0-4668-9872-A8C1E7132607 Q52870411-D7F0C92B-A58C-4EFC-B57F-DCE8D07D122E

P2860

Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus.

http://www.wikidata.org/entity/Q33591655

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Homeostatic imbalance of regul ...... vation amplifies murine lupus.

@ast

Homeostatic imbalance of regul ...... vation amplifies murine lupus.

@en

type

label

Homeostatic imbalance of regul ...... vation amplifies murine lupus.

@ast

Homeostatic imbalance of regul ...... vation amplifies murine lupus.

@en

prefLabel

Homeostatic imbalance of regul ...... vation amplifies murine lupus.

@ast

Homeostatic imbalance of regul ...... vation amplifies murine lupus.

@en

P1433

Q33591655-1D8AF159-4EF7-47C6-920E-29B53813A639

P1476

Q33591655-C0AF65EB-BB2B-44E0-B6E4-DF2670AD36BF

P2093

Q33591655-11AB9506-2D31-4D90-B807-8B3B4B53E42D

Q33591655-2594D528-DA42-40AB-8513-A906C099C880

Q33591655-54CB5536-1804-4FF7-997D-814AAEE758E8

Q33591655-5589215F-9177-45FF-B576-3EC1FD7D2900

Q33591655-5B76D936-9E79-4E16-8332-8F0BC8C34E0C

Q33591655-713C1E3A-3D86-4FE4-BF02-34789DCF0820

Q33591655-7DD6F833-09DE-42EB-AADD-2888A61232B7

Q33591655-8A9F03EE-73BF-4621-8CA5-910D13690908

Q33591655-92E7E948-4685-4EC4-8178-532DB466B1CF

Q33591655-AC461844-87F0-47A4-A194-5F6B0AD8337C

P2860

Q33591655-0377B00F-3560-4DC5-B417-2871CB31641D

Q33591655-0DF85875-057C-4B4E-A48C-1C56D7606D20

Q33591655-1C36F198-9190-4E5C-9496-1373D92DCBBA

Q33591655-28D9CA01-8F72-494D-9BE7-C32700309BE0

Q33591655-2AE59E7E-A929-4695-BC28-AD449E9B071E

Q33591655-2C74FC61-FA45-473E-998A-B312A0ACF076

Q33591655-3DE39AFC-A7C2-4D20-8D6B-49FFE240E487

Q33591655-50F812FC-6135-4056-B2F5-C198FCF0D809

Q33591655-53E092C9-51AE-4918-B889-68FEDC92652A

Q33591655-6315F911-5390-42D0-9D3E-C6FDCF7A3C77

P304

Q33591655-CF3EB3EB-3FAE-46FD-A56E-537E8693C6F1

P31

Q33591655-1B9C9B99-E33C-4C12-A12A-0BB64B8AC181

P356

Q33591655-5D06CC89-0AC2-4A55-ADA2-280039B83DF3

P407

Q33591655-AEEF6F46-C320-4DA7-AB3C-628CCD8C2048

P433

Q33591655-A9A5F2E4-E77A-49D6-9873-BCA7DD4FD9AF

P478

Q33591655-68A2B267-42F0-477E-83CA-7F937D029553

P50

Q33591655-12A7AB46-3987-4004-87F3-634299521833

Q33591655-CD376C47-BDE5-4843-8A68-DEBB61CDC388

Q33591655-FCEFC3ED-27A0-478C-B7B9-8E3FA2D37F0A

P577

Q33591655-496A3561-A0FC-458D-8950-F737DA62801B

P5875

Q33591655-713515C9-4803-465F-AE4B-281E92A91925

P698

Q33591655-86D65C69-2855-4C86-85E7-999C9A28B90C

P932

Q33591655-8E47FB64-53FF-494D-A4A7-CC449CF20CAC

P356

PNAS.0903158107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Homeostatic imbalance of regul ...... vation amplifies murine lupus.

@en

P2093

Andreas Radbruch

http://www.w3.org/2001/XMLSchema#string

Henner Morbach

http://www.w3.org/2001/XMLSchema#string

Jens Y Humrich

http://www.w3.org/2001/XMLSchema#string

Jochen Huehn

http://www.w3.org/2001/XMLSchema#string

Juliane Heimann

http://www.w3.org/2001/XMLSchema#string

Lutz Kloke

http://www.w3.org/2001/XMLSchema#string

Olivia Weigert

http://www.w3.org/2001/XMLSchema#string

Philipp Enghard

http://www.w3.org/2001/XMLSchema#string

Reinmar Undeutsch

http://www.w3.org/2001/XMLSchema#string

Stefan Rosenberger

http://www.w3.org/2001/XMLSchema#string

P2860

Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

A function for interleukin 2 in Foxp3-expressing regulatory T cells

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.

Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells.

Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling.

P304

204-209

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0903158107

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

107

http://www.w3.org/2001/XMLSchema#string

P50

Gabriela Riemekasten

Alexander Scheffold

Gerd-Rüdiger Burmester

P577

2009-12-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

235615781

http://www.w3.org/2001/XMLSchema#string

P698

20018660

http://www.w3.org/2001/XMLSchema#string

P932

2806746

http://www.w3.org/2001/XMLSchema#string