Defective mismatch repair, microsatellite mutation bias, and variability in clinical cancer phenotypes
about
Replication slippage of the thermophilic DNA polymerases B and D from the Euryarchaeota Pyrococcus abyssiMolecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and diseaseThe Impact of Hedgehog Signaling Pathway on DNA Repair Mechanisms in Human CancerThe quiescent cellular state is Arf/p53-dependent and associated with H2AX downregulation and genome stabilityThe significance of genetics for cholangiocarcinoma developmentAberrant methylation of different DNA repair genes demonstrates distinct prognostic value for esophageal cancerExome-wide somatic microsatellite variation is altered in cells with DNA repair deficienciesThe causes and consequences of genetic heterogeneity in cancer evolutionDistribution of somatic mutations of cancer-related genes according to microsatellite instability status in Korean gastric cancer.Sequence context modulation of polycyclic aromatic hydrocarbon-induced mutagenesis.Human base excision repair creates a bias toward -1 frameshift mutationsIntegrated analysis of mismatch repair system in malignant astrocytomas.Different roles of eukaryotic MutS and MutL complexes in repair of small insertion and deletion loops in yeast.Expression of the mismatch repair gene hMLH1 is enhanced in non-small cell lung cancer with EGFR mutationsShed syndecan-2 enhances tumorigenic activities of colon cancer cells.Somatic microsatellite variability as a predictive marker for colorectal cancer and liver cancer progression.Frameshift mutagenesis: the roles of primer-template misalignment and the nonhomologous end-joining pathway in Saccharomyces cerevisiae.The role of intracellular calcium for the development and treatment of neuroblastoma.No Evidence for a Parent-of-Origin Specific Differentially Methylated Region Linked to RASGRF1.The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombinationImplication of microsatellite instability in human gastric cancers.Mutation hot spots in yeast caused by long-range clustering of homopolymeric sequencesMicrosatellite instability in Marek's disease virus infected primary chicken embryo fibroblasts.Microsatellite Instability of Gastric and Colorectal Cancers as a Predictor of Synchronous Gastric or Colorectal Neoplasms.Mutation rates, spectra, and genome-wide distribution of spontaneous mutations in mismatch repair deficient yeast.A mononucleotide repeat in PRRT2 is an important, frequent target of mismatch repair deficiency in cancer.The DNA damage response: Balancing the scale between cancer and ageing.Poly(ADP-ribose) polymerase (PARP) inhibitors: Exploiting a synthetic lethal strategy in the clinic.Tumor spectrum in lynch syndrome, DNA mismatch repair system and endogenous carcinogens.Genomics and epigenomics of colorectal cancer.Exploring the Mechanisms of Gastrointestinal Cancer Development Using Deep Sequencing Analysis.Impact of MLH1 expression on tumor evolution after curative surgical tumor resection in a murine orthotopic xenograft model for human MSI colon cancer.Helicobacter pylori-Mediated Genetic Instability and Gastric Carcinogenesis.Deficiency in DNA mismatch repair increases the rate of telomere shortening in normal human cells.Unstable DNA repair genes shaped by their own sequence modifying phenotypes.Identification of a novel deletion mutant strain in Saccharomyces cerevisiae that results in a microsatellite instability phenotype.Contribution of large genomic rearrangements in Italian Lynch syndrome patients: characterization of a novel alu-mediated deletion.High-accuracy lagging-strand DNA replication mediated by DNA polymerase dissociation.New therapeutic targets for pulmonary sarcomatoid carcinomas based on their genomic and phylogenetic profiles.Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair.
P2860
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P2860
Defective mismatch repair, microsatellite mutation bias, and variability in clinical cancer phenotypes
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Defective mismatch repair, mic ...... in clinical cancer phenotypes
@ast
Defective mismatch repair, mic ...... in clinical cancer phenotypes
@en
type
label
Defective mismatch repair, mic ...... in clinical cancer phenotypes
@ast
Defective mismatch repair, mic ...... in clinical cancer phenotypes
@en
prefLabel
Defective mismatch repair, mic ...... in clinical cancer phenotypes
@ast
Defective mismatch repair, mic ...... in clinical cancer phenotypes
@en
P2093
P2860
P1433
P1476
Defective mismatch repair, mic ...... in clinical cancer phenotypes
@en
P2093
Kristin A Eckert
Sandeep N Shah
Suzanne E Hile
P2860
P304
P356
10.1158/0008-5472.CAN-09-3049
P407
P577
2010-01-12T00:00:00Z