Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases.
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Epigenetics Offer New Horizons for Colorectal Cancer PreventionEpigenomics of leukemia: from mechanisms to therapeutic applicationsDietary factors and epigenetic regulation for prostate cancer preventionDietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cellsPlant flavone apigenin inhibits HDAC and remodels chromatin to induce growth arrest and apoptosis in human prostate cancer cells: in vitro and in vivo study.Attenuation of multi-targeted proliferation-linked signaling by 3,3'-diindolylmethane (DIM): from bench to clinic.Epigenetic modifications by dietary phytochemicals: implications for personalized nutritionPlant HDAC inhibitor chrysin arrest cell growth and induce p21WAF1 by altering chromatin of STAT response element in A375 cellsCancer chemoprevention by dietary polyphenols: promising role for epigenetics.Metabolism as a key to histone deacetylase inhibition.Chemoprevention in gastrointestinal physiology and disease. Targeting the progression of cancer with natural products: a focus on gastrointestinal cancer.Current Perspectives on Epigenetic Modifications by Dietary Chemopreventive and Herbal PhytochemicalsDietary Glucosinolates Sulforaphane, Phenethyl Isothiocyanate, Indole-3-Carbinol/3,3'-Diindolylmethane: Anti-Oxidative Stress/Inflammation, Nrf2, Epigenetics/Epigenomics and In Vivo Cancer Chemopreventive Efficacy.Epigenetic modifications of Nrf2 by 3,3'-diindolylmethane in vitro in TRAMP C1 cell line and in vivo TRAMP prostate tumors.Natural compound-derived epigenetic regulators targeting epigenetic readers, writers and erasers.Phytochemicals from cruciferous vegetables, epigenetics, and prostate cancer prevention.Natural indoles, indole-3-carbinol and 3,3'-diindolymethane, inhibit T cell activation by staphylococcal enterotoxin B through epigenetic regulation involving HDAC expression.Plant phytochemicals as epigenetic modulators: role in cancer chemoprevention.Epigenetic regulation of HDAC1 SUMOylation as an endogenous neuroprotection against Aβ toxicity in a mouse model of Alzheimer's disease.Regulating the regulators: the post-translational code of class I HDAC1 and HDAC2.Effects of deranged metabolism on epigenetic changes in cancer.Impact of Epigenetic Dietary Components on Cancer through Histone Modifications.Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors.Research on cruciferous vegetables, indole-3-carbinol, and cancer prevention: A tribute to Lee W. Wattenberg.Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed ω-6 peroxidation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs.Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges.3-(2-Bromoethyl)-indole inhibits the growth of cancer cells and NF-κB activation.Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells.Honokiol induces cell cycle arrest and apoptosis via inhibiting class I histone deacetylases in acute myeloid leukemia.A role for paralog-specific sumoylation in histone deacetylase 1 stability.Anticancer Natural Compounds as Epigenetic Modulators of Gene Expression3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells.Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylasesKnockdown of delta-5-desaturase promotes the anti-cancer activity of dihomo-γ-linolenic acid and enhances the efficacy of chemotherapy in colon cancer cells expressing COX-2.Two-cell embryos are more sensitive than blastocysts to AMPK-dependent suppression of anabolism and stemness by commonly used fertility drugs, a diet supplement, and stress.Molecular Mechanisms and Pathways as Targets for Cancer Prevention and Progression with Dietary Compounds.PI3K/mTOR mediate mitogen-dependent HDAC1 phosphorylation in breast cancer: a novel regulation of estrogen receptor expression.Assessing the Role of Paralog-Specific Sumoylation of HDAC1.Detection of Sumo Modification of Endogenous Histone Deacetylase 2 (HDAC2) in Mammalian Cells.
P2860
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P2860
Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Chemopreventive agent 3,3'-dii ...... class I histone deacetylases.
@ast
Chemopreventive agent 3,3'-dii ...... class I histone deacetylases.
@en
type
label
Chemopreventive agent 3,3'-dii ...... class I histone deacetylases.
@ast
Chemopreventive agent 3,3'-dii ...... class I histone deacetylases.
@en
prefLabel
Chemopreventive agent 3,3'-dii ...... class I histone deacetylases.
@ast
Chemopreventive agent 3,3'-dii ...... class I histone deacetylases.
@en
P2093
P2860
P1433
P1476
Chemopreventive agent 3,3'-dii ...... class I histone deacetylases.
@en
P2093
P2860
P304
P356
10.1158/0008-5472.CAN-09-1924
P407
P577
2010-01-12T00:00:00Z