Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis - Wikidata - wikimedia - TriplyDB

Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis

Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis

http://www.wikidata.org/entity/Q33599539

about

The actinobacterial transcription factor RbpA binds to the principal sigma subunit of RNA polymerase An Alternative σ Factor, σ8, Controls Avermectin Production and Multiple Stress Responses in Streptomyces avermitilis.Systematics-guided bioprospecting for bioactive microbial natural products.A marine-derived Streptomyces sp. MS449 produces high yield of actinomycin X2 and actinomycin D with potent anti-tuberculosis activity.Genome plasticity and systems evolution in Streptomyces.Exploring anti-TB leads from natural products library originated from marine microbes and medicinal plants.Verrucisidinol and verrucosidinol acetate, two pyrone-type polyketides isolated from a marine derived fungus, Penicillium aurantiogriseum Endophytic Streptomyces sp. Y3111 from traditional Chinese medicine produced antitubercular pluramycins.FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains.A novel TetR family transcriptional regulator, SAV576, negatively controls avermectin biosynthesis in Streptomyces avermitilis.Exploiting a precise design of universal synthetic modular regulatory elements to unlock the microbial natural products in Streptomyces.Engineering of a genome-reduced host: practical application of synthetic biology in the overproduction of desired secondary metabolites.Tentative biosynthetic pathways of some microbial diketopiperazines.Synthetic biology of avermectin for production improvement and structure diversification.Recent advances in biochemistry and biotechnological synthesis of avermectins and their derivatives.Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes.Engineering microbial hosts for production of bacterial natural products Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp.Co-overexpression of lmbW and metK led to increased lincomycin A production and decreased byproduct lincomycin B content in an industrial strain of Streptomyces lincolnensis.Sigma factor WhiGch positively regulates natamycin production in Streptomyces chattanoogensis L10.Rational selection and engineering of exogenous principal sigma factor (σ(HrdB)) to increase teicoplanin production in an industrial strain of Actinoplanes teichomyceticus.An insight into the "-omics" based engineering of streptomycetes for secondary metabolite overproduction.Heterologous expression of Avermectins biosynthetic gene cluster by construction of a Bacterial Artificial Chromosome library of the producers.Overexpression of metK shows different effects on avermectin production in various Streptomyces avermitilis strains.Interrogation of Streptomyces avermitilis for efficient production of avermectins.AvaR1, a Butenolide-Type Autoregulator Receptor in Streptomyces avermitilis, Directly Represses Avenolide and Avermectin Biosynthesis and Multiple Physiological Responses.AvaR2, a pseudo γ-butyrolactone receptor homologue from Streptomyces avermitilis, is a pleiotropic repressor of avermectin and avenolide biosynthesis and cell growth.Connecting Metabolic Pathways: Sigma Factors in Streptomyces spp.Synergistic antifungal indolecarbazoles from Streptomyces sp. CNS-42 associated with traditional Chinese medicine Alisma orientale.Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis.An extracytoplasmic function sigma factor, σ(25), differentially regulates avermectin and oligomycin biosynthesis in Streptomyces avermitilis.The PhoP transcription factor negatively regulates avermectin biosynthesis in Streptomyces avermitilis.Different fates of avermectin and artemisinin in China.6S RNA modulates growth and antibiotic production in Streptomyces coelicolor.Organic Peroxide-Sensing Repressor OhrR Regulates Organic Hydroperoxide Stress Resistance and Avermectin Production in Streptomyces avermitilis.Activation of microbial secondary metabolic pathways: Avenues and challenges

P2860

Q27677480-BC81C514-0781-49E9-9BC4-781727889B70 Q33594456-A479B231-0D35-46FA-A2C6-941F60460A86 Q34075215-033B6A25-3FA9-48AB-A567-BF87EA3DCB2F Q34250434-68C36656-358A-4776-87AD-49B00FE4BCB9 Q34324723-992C08CB-9089-4252-969B-A7DD7F5FC521 Q34344261-F5E70C62-47E6-4F12-8322-7DCE1AF4F91B Q34374387-9D25A7A6-8A19-4147-BAA8-24A90D9DDF7E Q34382525-93F6F526-BD0F-498B-9C62-18DF47B24B98 Q34452917-306E30BE-557A-4F43-9BD7-15F508A6528C Q34883444-EB0DF7B1-6B5E-4728-AF1A-FDA2479F6FB1 Q34963865-8B4C9704-F3CE-436F-B80F-A4929C7B026D Q36120216-02764413-2C04-4154-ACB4-A9EA3F11F0D6 Q37825819-64949230-6D88-4B81-BE06-D5F0B68D95AE Q38129759-327594AE-443B-44A3-ABB7-EA9AA2A97F48 Q38183353-10D7E7D6-E02E-4619-9F16-8B1A0A1A17D5 Q38237973-833D1CCC-AD54-4F45-BF5D-826371E87E06 Q38585753-3BC997DD-FA9E-451F-ABD3-E73A19F49E7C Q38806940-4679DB81-C63C-460B-A9A1-A636CEF2210B Q40314872-13E13623-ABA7-497F-BAC3-E68CA0B9206C Q40653474-7E358A85-26C7-40E3-88BF-F695D5F2F63C Q41338359-DB62B240-F332-4068-A185-B0C7A5E1A1BE Q41883507-93F94AB7-5603-4788-A355-5A301888F43C Q42181821-24575124-20E0-4F22-9E67-6E7A0CD4CA5B Q45327233-2792CBF4-B8B7-45F8-BA49-4BDB6758C609 Q45804011-4ADF13A0-12A6-4ACE-BB0C-9C3DF939AE02 Q47139111-9C9BCB18-B3A6-4425-9048-18C12C0F0E03 Q47221440-93086D86-2C24-4739-A3B0-598599736B18 Q49129905-3CEAB95C-E94A-402E-94C2-C3A9F95F184E Q49632033-A14F96B5-0AA6-487C-AE24-BCB85646CC87 Q51051298-7962E12E-BC5F-45AF-9151-6CFB1ECFB1F4 Q52723564-5E32C942-D50D-4809-994F-896FB95CF11D Q52771260-DF202455-9946-4601-BD2C-7B4B11F85FAE Q52815490-ABD89193-455B-4192-8BE6-82486425733C Q52848095-894E0FDB-4819-4A67-92CB-54651E61CD12 Q54350099-450EC1A8-F9BA-46D5-9DAD-78714217A2B8 Q55658992-355A7AEC-921B-402C-918B-5A043ED172D6 Q57822331-2EEFA08F-E65B-4A15-8BD6-A5CECF682C5C

P2860

Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis

http://www.wikidata.org/entity/Q33599539

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Reverse biological engineering ...... in of Streptomyces avermitilis

@ast

Reverse biological engineering ...... in of Streptomyces avermitilis

@en

type

label

Reverse biological engineering ...... in of Streptomyces avermitilis

@ast

Reverse biological engineering ...... in of Streptomyces avermitilis

@en

prefLabel

Reverse biological engineering ...... in of Streptomyces avermitilis

@ast

Reverse biological engineering ...... in of Streptomyces avermitilis

@en

P1433

Q33599539-4D082943-F07D-4E62-A769-EDE63C90F8CD

P1476

Q33599539-E56C6640-1E74-4184-ADA0-ECA25B6CD470

P2093

Q33599539-02417B4E-B4CD-40B2-9094-EC771A79F668

Q33599539-2447A668-8EC3-463A-8040-A14DB5DE57FD

Q33599539-3EA4C229-F90D-4A19-A9EE-2697CDFAA864

Q33599539-7E1E3D40-43D1-4983-86DE-088C1E9CBDAD

Q33599539-7FF30621-0D5C-4877-BD21-768D6B3128CD

Q33599539-9662CF7A-55C8-4756-B64A-2B454886A33C

Q33599539-9A584304-7C7D-4BA0-A498-CB7A48286C45

Q33599539-9F8F1293-D513-4022-BEE4-6FE5BA9B0B56

Q33599539-EC2A4584-38C5-4097-A122-3AC344096F5B

Q33599539-F897C0D2-1475-4439-8184-A97009153C93

P2860

Q33599539-0D3AD07D-E3F9-4BA8-BCBE-C85BA8E5299D

Q33599539-164A038D-19D6-4D70-9F1E-005D10D1BA9A

Q33599539-193F994A-CB3A-4FFF-8633-7A2101241381

Q33599539-1DA3DEFE-0E39-47DA-94F4-658435786986

Q33599539-2DE5B809-CC27-4CBB-9DAF-B7B4B39E6120

Q33599539-2F8FC2AF-671F-433D-ABB7-373E47111016

Q33599539-3743919D-E27D-4594-A31F-9FEEA5559A75

Q33599539-39C41D0B-8492-4538-B501-CCE1F5D7B43A

Q33599539-4AD14951-2E0D-4B4C-83D0-415789360CA4

Q33599539-4C694243-2E92-4A17-BCC0-33FB1A8380D9

P304

Q33599539-0652C456-3482-4BB1-B8CB-74437E07A116

P31

Q33599539-6A4C02D7-E93A-4FA6-8F3E-4BDEBD3D07C6

P356

Q33599539-1D7B42E9-D17E-4F15-B075-E2AB5B18FB9A

P407

Q33599539-30FB2B63-D7E2-41D0-B3DB-15E022122ABC

P433

Q33599539-3054752C-9127-404A-B3ED-59AD301D9A49

P478

Q33599539-5E5C5350-2A47-490F-983C-8165D4771F2B

P50

Q33599539-2E87C256-6A0A-4A50-8A76-6840514009CD

Q33599539-34D31821-2ACA-4294-9DB7-2DFE453D0FBA

P577

Q33599539-A1C56172-CF98-4646-9492-D0CB9574FD13

P5875

Q33599539-145DA980-A793-4415-84F4-147A5361D70B

P698

Q33599539-45C596C5-6D1C-43DE-B897-FB220677AE44

P932

Q33599539-A803D96C-23CE-4E67-8CCC-705035B53702

P356

PNAS.1006085107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Reverse biological engineering ...... in of Streptomyces avermitilis

@en

P2093

Bang-Ce Ye

http://www.w3.org/2001/XMLSchema#string

Difei Chen

http://www.w3.org/2001/XMLSchema#string

Li-Xin Zhang

http://www.w3.org/2001/XMLSchema#string

Mei Liu

http://www.w3.org/2001/XMLSchema#string

Qing Zhang

http://www.w3.org/2001/XMLSchema#string

Siliang Zhang

http://www.w3.org/2001/XMLSchema#string

Wenquan Zhang

http://www.w3.org/2001/XMLSchema#string

Xianlong Zhou

http://www.w3.org/2001/XMLSchema#string

Ying Zhuo

http://www.w3.org/2001/XMLSchema#string

Zhongxuan Gou

http://www.w3.org/2001/XMLSchema#string

P2860

The sigma70 family of sigma factors

Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites

Avermectins, new family of potent anthelmintic agents: producing organism and fermentation

Avermectin: biochemical and molecular basis of its biosynthesis and regulation

The TetR family of transcriptional repressors.

The novel Streptomyces olivaceoviridis ABC transporter Ngc mediates uptake of N-acetylglucosamine and N,N'-diacetylchitobiose.

SIGffRid: a tool to search for sigma factor binding sites in bacterial genomes using comparative approach and biologically driven statistics.

A high-throughput screen for hyaluronic acid accumulation in recombinant Escherichia coli transformed by libraries of engineered sigma factors.

SigN is responsible for differentiation and stress responses based on comparative proteomic analyses of Streptomyces coelicolor wild-type and sigN deletion strains.

Pharmaceutically active secondary metabolites of microorganisms.

P304

11250-11254

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1006085107

http://www.w3.org/2001/XMLSchema#string

P407

P433

25

http://www.w3.org/2001/XMLSchema#string

P478

107

http://www.w3.org/2001/XMLSchema#string

P50

P577

2010-06-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

44660168

http://www.w3.org/2001/XMLSchema#string

P698

20534557

http://www.w3.org/2001/XMLSchema#string

P932

2895102

http://www.w3.org/2001/XMLSchema#string