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Modeling stochastic gene expression: implications for haploinsufficiency.

Modeling stochastic gene expression: implications for haploinsufficiency.

http://www.wikidata.org/entity/Q33603649

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Slow, stochastic transgene repression with properties of a timer Severe pancreas hypoplasia and multicystic renal dysplasia in two human fetuses carrying novel HNF1beta/MODY5 mutations Fluctuations in repressor control: thermodynamic constraints on stochastic focusing.Near-critical phenomena in intracellular metabolite pools FLI1 monoallelic expression combined with its hemizygous loss underlies Paris-Trousseau/Jacobsen thrombopenia Random monoallelic expression of three genes clustered within 60 kb of mouse t complex genomic DNA Intrinsic noise in gene regulatory networks Stochastic focusing: fluctuation-enhanced sensitivity of intracellular regulation A basis for a visual language for describing, archiving and analyzing functional models of complex biological systems Ultrasensitization: switch-like regulation of cellular signaling by transcriptional induction Modeling T cell antigen discrimination based on feedback control of digital ERK responses X chromosome inactivation and active X upregulation in therian mammals: facts, questions, and hypotheses CALL gene is haploinsufficient in a 3p- syndrome patient Stochasticity in transcriptional regulation: origins, consequences, and mathematical representations Expression variation: its relevance to emergence of chronic disease and to therapy APC-dependent suppression of colon carcinogenesis by PPARgamma Modulation of Aire regulates the expression of tissue-restricted antigens Quantifying intrinsic and extrinsic variability in stochastic gene expression models Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype.Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization Intraclonal protein expression heterogeneity in recombinant CHO cells Role of mef2ca in developmental buffering of the zebrafish larval hyoid dermal skeleton.Inference of gene regulatory networks from genome-wide knockout fitness data Hybrid stochastic simplifications for multiscale gene networks.Effects of transcriptional pausing on gene expression dynamics.'Particle genetics': treating every cell as unique.The role of noise and positive feedback in the onset of autosomal dominant diseases.Conflict between noise and plasticity in yeast.Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma.Tuning and controlling gene expression noise in synthetic gene networks.Parallel solutions for voxel-based simulations of reaction-diffusion systems.Theoretical basis of the community effect in development.Altered dynamics of intestinal cell maturation in Apc1638N/+ mice.Interpretation of array comparative genome hybridization data: a major challenge.Mutations in genes encoding subunits of RNA polymerases I and III cause Treacher Collins syndrome.Increased noise as an effect of haploinsufficiency of the tumor-suppressor gene neurofibromatosis type 1 in vitro.Self-consistent proteomic field theory of stochastic gene switches.The genetic control of growth rate: a systems biology study in yeast.Modeling regulation of zinc uptake via ZIP transporters in yeast and plant roots Dynamics of protein noise can distinguish between alternate sources of gene-expression variability.

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P2860

Modeling stochastic gene expression: implications for haploinsufficiency.

http://www.wikidata.org/entity/Q33603649

description

1998 nî lūn-bûn

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1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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name

Modeling stochastic gene expression: implications for haploinsufficiency.

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Modeling stochastic gene expression: implications for haploinsufficiency.

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Modeling stochastic gene expression: implications for haploinsufficiency.

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Modeling stochastic gene expression: implications for haploinsufficiency.

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Modeling stochastic gene expression: implications for haploinsufficiency.

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Modeling stochastic gene expression: implications for haploinsufficiency.

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Proceedings of the National Academy of Sciences of the United States of America

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Modeling stochastic gene expression: implications for haploinsufficiency.

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A N Gerber

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D L Cook

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S J Tapscott

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P2860

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

A zinc-finger gene ZNF141 mapping at 4p16.3/D4S90 is a candidate gene for the Wolf-Hirschhorn (4p-) syndrome

Mutations of the RET proto-oncogene in Hirschsprung's disease

Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region

SOX10 mutations in patients with Waardenburg-Hirschsprung disease

Isolation of a Miller-Dieker lissencephaly gene containing G protein beta-subunit-like repeats

A novel germ line mutation in SOX9 causes familial campomelic dysplasia and sex reversal

Stochastic mechanisms in gene expression

The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes

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haploinsufficiency

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