Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice.
about
AROS has a context-dependent effect on SIRT1Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of PparγHDAC3 is negatively regulated by the nuclear protein DBC1DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbαSRT1720 improves survival and healthspan of obese micePotential Modulation of Sirtuins by Oxidative StressEpigenetic mechanisms underlying the link between non-alcoholic fatty liver diseases and nutritionSirtuins as regulators of metabolism and healthspanTargeting sirtuin 1 to improve metabolism: all you need is NAD(+)?The role of mammalian sirtuins in the regulation of metabolism, aging, and longevityEnergy metabolism in the liverSirtuin deacylases: a molecular link between metabolism and immunitySIRT1 activators suppress inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activityA nutrient-sensitive interaction between Sirt1 and HNF-1α regulates Crp expressionSirt1 carboxyl-domain is an ATP-repressible domain that is transferrable to other proteins.SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylationThe ways and means that fine tune Sirt1 activity.Impact of Sirt1 on mammalian aging.Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice.Deleted in Breast Cancer 1 regulates cellular senescence during obesityHigh-fat diet-induced impairment of skeletal muscle insulin sensitivity is not prevented by SIRT1 overexpression.DBC1 is a suppressor of B cell activation by negatively regulating alternative NF-κB transcriptional activity.Multi-omic data integration links deleted in breast cancer 1 (DBC1) degradation to chromatin remodeling in inflammatory responseDeleted in breast cancer 1 limits adipose tissue fat accumulation and plays a key role in the development of metabolic syndrome phenotypeMitochondrial longevity pathwaysHepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liverSirtuin-1 regulation of mammalian metabolismThe expression of DBC1/CCAR2 is associated with poor prognosis of ovarian carcinomaDBC1 functions as a tumor suppressor by regulating p53 stabilitySirtuin 1 in lipid metabolism and obesity.A divergent role of the SIRT1-TopBP1 axis in regulating metabolic checkpoint and DNA damage checkpoint.Sirtuin 1 signaling and alcoholic fatty liver disease.KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining RepairThe c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.Hepatic SirT1-Dependent Gain of Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions.Inflammation negatively regulates FOXP3 and regulatory T-cell function via DBC1.NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the NucleusMetabolic actions of hypothalamic SIRT1SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington's Disease Mice.Systemic regulation of mammalian ageing and longevity by brain sirtuins.
P2860
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P2860
Deleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Deleted in breast cancer-1 reg ...... duced liver steatosis in mice.
@ast
Deleted in breast cancer-1 reg ...... duced liver steatosis in mice.
@en
type
label
Deleted in breast cancer-1 reg ...... duced liver steatosis in mice.
@ast
Deleted in breast cancer-1 reg ...... duced liver steatosis in mice.
@en
prefLabel
Deleted in breast cancer-1 reg ...... duced liver steatosis in mice.
@ast
Deleted in breast cancer-1 reg ...... duced liver steatosis in mice.
@en
P2093
P2860
P356
P1476
Deleted in breast cancer-1 reg ...... duced liver steatosis in mice.
@en
P2093
Carlos Escande
Claudia C S Chini
Colleen M Novak
Eduardo Nunes Chini
James Levine
Jan van Deursen
Junjie Chen
Katherine Minter Dykhouse
Veronica Nin
Zhenkun Lou
P2860
P304
P356
10.1172/JCI39319
P407
P577
2010-01-11T00:00:00Z