Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13.
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Proteolytic processing of von Willebrand factor by adamts13 and leukocyte proteasesRegulation of thrombosis and vascular function by protein methionine oxidationStructural basis of type 2A von Willebrand disease investigated by molecular dynamics simulations and experimentsMolecular Imaging of Platelet-Endothelial Interactions and Endothelial von Willebrand Factor in Early and Mid-Stage AtherosclerosisThe rate of hemolysis in sickle cell disease correlates with the quantity of active von Willebrand factor in the plasma.Cocaine and specific cocaine metabolites induce von Willebrand factor release from endothelial cells in a tissue-specific manner.Antigen and substrate withdrawal in the management of autoimmune thrombotic disorders.The oxidative modification of von Willebrand factor is associated with thrombotic angiopathies in diabetes mellitusVWF excess and ADAMTS13 deficiency: a unifying pathomechanism linking inflammation to thrombosis in DIC, malaria, and TTP.Thrombocytopenia-Associated Multiple Organ Failure and Acute Kidney Injury.High-density lipoprotein modulates thrombosis by preventing von Willebrand factor self-association and subsequent platelet adhesion.Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis.Hypochlorous acid generated by neutrophils inactivates ADAMTS13: an oxidative mechanism for regulating ADAMTS13 proteolytic activity during inflammation.Shear stress-induced unfolding of VWF accelerates oxidation of key methionine residues in the A1A2A3 region.Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor.Deletion of Methionine Sulfoxide Reductase A Does Not Affect Atherothrombosis but Promotes Neointimal Hyperplasia and Extracellular Signal-Regulated Kinase 1/2 Signaling.Acquired von Willebrand syndrome associated with left ventricular assist device.von Willebrand factor: at the crossroads of bleeding and thrombosis.von Willebrand factor: the old, the new and the unknown.Interplay between coagulation and vascular inflammation in sickle cell disease.Potential value of targeting von Willebrand factor in atherosclerotic cardiovascular disease.Platelets and von Willebrand factor in atherogenesis.The ADAMTS13 metalloprotease domain: roles of subsites in enzyme activity and specificity.Glycoprotein Ib-IX-V Complex Transmits Cytoskeletal Forces That Enhance Platelet Adhesion.Oxidized von Willebrand factor is efficiently cleaved by serine proteases from primary granules of leukocytes: divergence from ADAMTS-13.ADAMTS-13 metalloprotease abnormalities in systemic lupus erythematosus: is there a correlation with disease status?Oxidation of Met1606 in von Willebrand factor is a risk factor for thrombotic and septic complications in chronic renal failure.Quantification of Von Willebrand Factor Cleavage by adamts-13 in Patients Supported by Left Ventricular Assist Devices.Pathophysiology of thrombotic thrombocytopenic purpura.Dynamics of von Willebrand factor reactivity in sickle cell disease during vaso-occlusive crisis and steady state.Evaluation of von Willebrand factor and ADAMTS-13 antigen and activity levels in sickle cell disease patients in Kuwait.Platelet-neutrophil interactions as drivers of inflammatory and thrombotic disease.Autoregulation of von Willebrand factor function by a disulfide bond switch.Destabilization of the von Willebrand factor A2 domain under oxidizing conditions investigated by molecular dynamics simulations
P2860
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P2860
Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13.
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Oxidative modification of von ...... bits its cleavage by ADAMTS13.
@ast
Oxidative modification of von ...... bits its cleavage by ADAMTS13.
@en
type
label
Oxidative modification of von ...... bits its cleavage by ADAMTS13.
@ast
Oxidative modification of von ...... bits its cleavage by ADAMTS13.
@en
prefLabel
Oxidative modification of von ...... bits its cleavage by ADAMTS13.
@ast
Oxidative modification of von ...... bits its cleavage by ADAMTS13.
@en
P2093
P2860
P1433
P1476
Oxidative modification of von ...... bits its cleavage by ADAMTS13.
@en
P2093
Brad McMullen
Dominic W Chung
John Kulman
José A López
Junmei Chen
Minhua Ling
Xiaoyun Fu
P2860
P304
P356
10.1182/BLOOD-2009-03-213967
P407
P577
2009-10-07T00:00:00Z