A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2 - Wikidata - wikimedia - TriplyDB

A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2

A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2

http://www.wikidata.org/entity/Q33609662

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Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication Animal and human mucosal tissue models to study HIV biomedical interventions: can we predict success?Prodrugs of phosphonates and phosphates: crossing the membrane barrier HSV neutralization by the microbicidal candidate C5A Conformational analysis, molecular structure and solid state simulation of the antiviral drug acyclovir (zovirax) using density functional theory methods.Herpes simplex virus-induced epithelial damage and susceptibility to human immunodeficiency virus type 1 infection in human cervical organ culture.Use of human mucosal tissue to study HIV-1 pathogenesis and evaluate HIV-1 prevention modalities.Update on emerging antivirals for the management of herpes simplex virus infections: a patenting perspective.Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity.Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin Short communication: T cell activation in HIV-1/herpes simplex virus-2-coinfected Kenyan women receiving valacyclovir Microbicides: still a long road to success Drug transporter pharmacogenetics in nucleoside-based therapies.Herpes simplex virus and HIV: genital infection synergy and novel approaches to dual prevention.Virtual screening of acyclovir derivatives as potential antiviral agents: design, synthesis and biological evaluation of new acyclic nucleoside ProTides.

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P2860

A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2

http://www.wikidata.org/entity/Q33609662

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

A new class of dual-targeted a ...... nd herpes simplex virus type 2

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A new class of dual-targeted a ...... nd herpes simplex virus type 2

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A new class of dual-targeted a ...... nd herpes simplex virus type 2

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A new class of dual-targeted a ...... nd herpes simplex virus type 2

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The Journal of Infectious Diseases

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A new class of dual-targeted a ...... nd herpes simplex virus type 2

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Andrea Lisco

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Beda Brichacek

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Christophe Vanpouille

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Christopher McGuigan

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Elisa Saba

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Francesca Scrimieri

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Leonid Margolis

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Marco Derudas

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P2860

Mechanism of anti-HIV action of masked alaninyl d4T-MP derivatives

Enzyme-catalyzed therapeutic agent (ECTA) design: activation of the antitumor ECTA compound NB1011 by thymidylate synthase.

Genital herpes has played a more important role than any other sexually transmitted infection in driving HIV prevalence in Africa.

Effect of HSV-2 serostatus on acquisition of HIV by young men: results of a longitudinal study in Orange Farm, South Africa.

Human immunodeficiency virus type 1 (HIV-1) non-B subtypes are similar to HIV-1 subtype B in that coreceptor specificity is a determinant of cytopathicity in human lymphoid tissue infected ex vivo.

Differential pathogenesis of primary CCR5-using human immunodeficiency virus type 1 isolates in ex vivo human lymphoid tissue.

Impact of aciclovir on genital and plasma HIV-1 RNA in HSV-2/HIV-1 co-infected women: a randomized placebo-controlled trial in South Africa

Infection of human tonsil histocultures: a model for HIV pathogenesis.

Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues.

Application of phosphoramidate pronucleotide technology to abacavir leads to a significant enhancement of antiviral potency.

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635-643

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scholarly article

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10.1086/650343

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4

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201

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Dominique Schols

Jean-Charles Grivel

Raymond F. Schinazi

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2010-02-01T00:00:00Z

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41087601

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20085496

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