Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes.
about
The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIαThe schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapseAP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesisBLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organellesA global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transportThe dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowthThe Role of Copper Chaperone Atox1 in Coupling Redox Homeostasis to Intracellular Copper DistributionThe Development of Sugar-Based Anti-Melanogenic AgentsBLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery.Structure and Metal Loading of a Soluble Periplasm CuproproteinUpdate on the regulation of mammalian melanocyte function and skin pigmentationPhysiological factors that regulate skin pigmentationCopper metallochaperonesATP7A-related copper transport diseases-emerging concepts and future trendsHermansky-Pudlak protein complexes, AP-3 and BLOC-1, differentially regulate presynaptic composition in the striatum and hippocampusUnexpected role of the copper transporter ATP7A in PDGF-induced vascular smooth muscle cell migrationAdaptor Protein-1 Complex Affects the Endocytic Trafficking and Function of Peptidylglycine α-Amidating Monooxygenase, a Luminal CuproenzymeRoles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesiclesCopper active sites in biologyDysbindin-containing complexes and their proposed functions in brain: from zero to (too) many in a decade.Electron tomography of early melanosomes: implications for melanogenesis and the generation of fibrillar amyloid sheets.BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling EndosomesBLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriersC-terminus glycans with critical functional role in the maturation of secretory glycoproteins.A data-mining approach to rank candidate protein-binding partners-The case of biogenesis of lysosome-related organelles complex-1 (BLOC-1).Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency.Mammalian copper-transporting P-type ATPases, ATP7A and ATP7B: emerging roles.Rab7 is a critical mediator in vesicular transport of tyrosinase-related protein 1 in melanocytes.Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenicCombined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation.3D imaging of transition metals in the zebrafish embryo by X-ray fluorescence microtomography.C. elegans BLOC-1 functions in trafficking to lysosome-related gut granules.Myosin vc interacts with Rab32 and Rab38 proteins and works in the biogenesis and secretion of melanosomesFunctional interactions between OCA2 and the protein complexes BLOC-1, BLOC-2, and AP-3 inferred from epistatic analyses of mouse coat pigmentationComparative genomics of trace element dependence in biology.Thermodynamics of copper and zinc distribution in the cyanobacterium Synechocystis PCC 6803The N-ethylmaleimide-sensitive factor and dysbindin interact to modulate synaptic plasticity.Membrane-Associated Transporter Protein (MATP) Regulates Melanosomal pH and Influences Tyrosinase ActivityCopper-transporting P-type adenosine triphosphatase (ATP7A) is associated with platinum-resistance in non-small cell lung cancer (NSCLC).Cell biology of the BLOC-1 complex subunit dysbindin, a schizophrenia susceptibility gene.
P2860
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P2860
Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Cell-specific ATP7A transport ...... inase activity in melanosomes.
@ast
Cell-specific ATP7A transport ...... inase activity in melanosomes.
@en
type
label
Cell-specific ATP7A transport ...... inase activity in melanosomes.
@ast
Cell-specific ATP7A transport ...... inase activity in melanosomes.
@en
prefLabel
Cell-specific ATP7A transport ...... inase activity in melanosomes.
@ast
Cell-specific ATP7A transport ...... inase activity in melanosomes.
@en
P2860
P50
P356
P1433
P1476
Cell-specific ATP7A transport ...... inase activity in melanosomes.
@en
P2093
Elena V Sviderskaya
Graça Raposo
P2860
P2888
P304
P356
10.1038/NATURE07163
P407
P577
2008-07-23T00:00:00Z
P5875
P6179
1043996256