CD8+ T cell concentration determines their efficiency in killing cognate antigen-expressing syngeneic mammalian cells in vitro and in mouse tissues
about
Combining radiotherapy and cancer immunotherapy: a paradigm shiftA biased competition theory of cytotoxic T lymphocyte interaction with tumor nodulesEnhancing the discovery and development of immunotherapies for cancer using quantitative and systems pharmacology: Interleukin-12 as a case studyPathogen-related differences in the abundance of presented antigen are reflected in CD4+ T cell dynamic behavior and effector function in the lung.A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agentsViral replication rate regulates clinical outcome and CD8 T cell responses during highly pathogenic H5N1 influenza virus infection in miceRelapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinityPeripheral prepositioning and local CXCL9 chemokine-mediated guidance orchestrate rapid memory CD8+ T cell responses in the lymph node.Why don't CD8+ T cells reduce the lifespan of SIV-infected cells in vivo?Evaluating the cellular targets of anti-4-1BB agonist antibody during immunotherapy of a pre-established tumor in mice.MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degenerationKilling of targets by CD8 T cells in the mouse spleen follows the law of mass action.Spatial heterogeneity and peptide availability determine CTL killing efficiency in vivo.Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells.GITR pathway activation abrogates tumor immune suppression through loss of regulatory T cell lineage stability.IL-27 is required for shaping the magnitude, affinity distribution, and memory of T cells responding to subunit immunization.Theiler's murine encephalomyelitis virus as a vaccine candidate for immunotherapy.Expression of EPHRIN-A1, SCINDERIN and MHC class I molecules in head and neck cancers and relationship with the prognostic value of intratumoral CD8+ T cells.Combination of alphavirus replicon particle-based vaccination with immunomodulatory antibodies: therapeutic activity in the B16 melanoma mouse model and immune correlates.CD8(+) T cell response to adenovirus vaccination and subsequent suppression of tumor growth: modeling, simulation and analysisNon-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints.Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotypeHow many neutrophils are enough (redux, redux)?Efficacy of systemic adoptive transfer immunotherapy targeting NY-ESO-1 for glioblastomaT Cell Vaccinology: Beyond the Reflection of Infectious ResponsesClonal Abundance of Tumor-Specific CD4(+) T Cells Potentiates Efficacy and Alters Susceptibility to ExhaustionSTIM1 and STIM2-mediated Ca(2+) influx regulates antitumour immunity by CD8(+) T cellsAnnular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse.Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy.Harnessing the immunomodulatory effect of thermal and non-thermal ablative therapies for cancer treatment.The memory of a killer T cell: models of CD8(+) T cell differentiation.Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy.T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy.Molecular mechanisms involved in dendritic cell dysfunction in cancer.A general functional response of cytotoxic T lymphocyte-mediated killing of target cells.3D porous chitosan-alginate scaffolds: a new matrix for studying prostate cancer cell-lymphocyte interactions in vitro.Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment.Combat or surveillance? Evaluation of the heterogeneous inflammatory breast cancer microenvironment.NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade.How is the effectiveness of immune surveillance impacted by the spatial distribution of spreading infections?
P2860
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P2860
CD8+ T cell concentration determines their efficiency in killing cognate antigen-expressing syngeneic mammalian cells in vitro and in mouse tissues
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
CD8+ T cell concentration dete ...... in vitro and in mouse tissues
@ast
CD8+ T cell concentration dete ...... in vitro and in mouse tissues
@en
type
label
CD8+ T cell concentration dete ...... in vitro and in mouse tissues
@ast
CD8+ T cell concentration dete ...... in vitro and in mouse tissues
@en
prefLabel
CD8+ T cell concentration dete ...... in vitro and in mouse tissues
@ast
CD8+ T cell concentration dete ...... in vitro and in mouse tissues
@en
P2093
P2860
P356
P1476
CD8+ T cell concentration dete ...... in vitro and in mouse tissues
@en
P2093
Andrei Constantinescu
Ashley Pandolfi
Geoffrey Catalano
John D Loike
Raphael Clynes
Sadna Budhu
Samuel C Silverstein
P2860
P304
P356
10.1084/JEM.20091279
P407
P577
2010-01-11T00:00:00Z