Role of the cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) domain in trafficking and stabilization of Kv11.1 channels. - Wikidata - wikimedia - TriplyDB

Role of the cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) domain in trafficking and stabilization of Kv11.1 channels.

Role of the cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) domain in trafficking and stabilization of Kv11.1 channels.

http://www.wikidata.org/entity/Q33619341

about

Translational toxicology and rescue strategies of the hERG channel dysfunction: biochemical and molecular mechanistic aspects Molecular Cloning and Functional Expression of the Equine K+ Channel KV11.1 (Ether à Go-Go-Related/KCNH2 Gene) and the Regulatory Subunit KCNE2 from Equine Myocardium Schizophrenia-Associated hERG channel Kv11.1-3.1 Exhibits a Unique Trafficking Deficit that is Rescued Through Proteasome Inhibition for High Throughput Screening hERG quality control and the long QT syndrome.Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations.Express with caution: Epitope tags and cDNA variants effects on hERG channel trafficking, half-life and function.Protein Inhibitor of Activated STAT (PIAS) Negatively Regulates the JAK/STAT Pathway by Inhibiting STAT Phosphorylation and Translocation

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P2860

Role of the cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) domain in trafficking and stabilization of Kv11.1 channels.

http://www.wikidata.org/entity/Q33619341

description

2014 nî lūn-bûn

@nan

2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Role of the cytoplasmic N-term ...... bilization of Kv11.1 channels.

@ast

Role of the cytoplasmic N-term ...... bilization of Kv11.1 channels.

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type

label

Role of the cytoplasmic N-term ...... bilization of Kv11.1 channels.

@ast

Role of the cytoplasmic N-term ...... bilization of Kv11.1 channels.

@en

prefLabel

Role of the cytoplasmic N-term ...... bilization of Kv11.1 channels.

@ast

Role of the cytoplasmic N-term ...... bilization of Kv11.1 channels.

@en

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P356

JBC.M113.531277

P1433

Journal of Biological Chemistry

P1476

Role of the cytoplasmic N-term ...... abilization of Kv11.1 channels

@en

P2093

Chai Ann Ng

http://www.w3.org/2001/XMLSchema#string

Mark J Hunter

http://www.w3.org/2001/XMLSchema#string

Matthew D Perry

http://www.w3.org/2001/XMLSchema#string

Ying Ke

http://www.w3.org/2001/XMLSchema#string

P2860

Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-á-go-go-related gene potassium channels

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

Structure of the redox sensor domain of Azotobacter vinelandii NifL at atomic resolution: signaling, dimerization, and mechanism

NMR solution structure of the N-terminal domain of hERG and its interaction with the S4-S5 linker

Mechanistic Insight into Human ether-a-go-go-related Gene (hERG) K+ Channel Deactivation Gating from the Solution Structure of the EAG Domain

The N–Terminal Tail of hERG Contains an Amphipathic α–Helix That Regulates Channel Deactivation

Structural properties of PAS domains from the KCNH potassium channels

The structural mechanism of KCNH-channel regulation by the eag domain.

Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain

Identification of the cyclic-nucleotide-binding domain as a conserved determinant of ion-channel cell-surface localization

P304

13782-13791

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scholarly article

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10.1074/JBC.M113.531277

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20

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289

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Jamie I. Vandenberg

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2014-04-02T00:00:00Z

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24695734

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4022852

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