Rescue of embryonic stem cells from cellular transformation by proteomic stabilization of mutant p53 and conversion into WT conformation.
about
Mutant p53: Multiple Mechanisms Define Biologic Activity in CancerContribution of the Type II Chaperonin, TRiC/CCT, to OncogenesisLa FAM fatale: USP9X in development and diseaseReprogramming of human cancer cells to pluripotency for models of cancer progressionProteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4.Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides.Clinical significance and prognostic value of TRIM24 expression in esophageal squamous cell carcinoma.Down-regulation of LATS kinases alters p53 to promote cell migration.Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cellsDouble mutant P53 (N340Q/L344R) promotes hepatocarcinogenesis through upregulation of Pim1 mediated by PKM2 and LncRNA CUDRPharmacological reactivation of p53 as a strategy to treat cancer.Mutant p53 upregulates alpha-1 antitrypsin expression and promotes invasion in lung cancer.p53 and its mutants on the slippery road from stemness to carcinogenesis.Oncogenic Mutant p53 Gain of Function Nourishes the Vicious Cycle of Tumor Development and Cancer Stem-Cell Formation.The Paradox of p53: What, How, and Why?DUB3 and USP7 de-ubiquitinating enzymes control replication inhibitor Geminin: molecular characterization and associations with breast cancer.The importance of regulatory ubiquitination in cancer and metastasis.The cancer paradigms of mammalian regeneration: can mammals regenerate as amphibians?p53 shades of Hippo.Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanism
P2860
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P2860
Rescue of embryonic stem cells from cellular transformation by proteomic stabilization of mutant p53 and conversion into WT conformation.
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Rescue of embryonic stem cells ...... nversion into WT conformation.
@ast
Rescue of embryonic stem cells ...... nversion into WT conformation.
@en
type
label
Rescue of embryonic stem cells ...... nversion into WT conformation.
@ast
Rescue of embryonic stem cells ...... nversion into WT conformation.
@en
prefLabel
Rescue of embryonic stem cells ...... nversion into WT conformation.
@ast
Rescue of embryonic stem cells ...... nversion into WT conformation.
@en
P2093
P2860
P356
P1476
Rescue of embryonic stem cells ...... onversion into WT conformation
@en
P2093
Alina Molchadsky
Maayan Doody
Michal Sheffer
Naomi Goldfinger
Noa Rivlin
Stav Horesh
Tamar Geiger
Varda Rotter
Yoav Shetzer
P2860
P304
P356
10.1073/PNAS.1320428111
P407
P577
2014-04-28T00:00:00Z