Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden
about
The Oct4 protein: more than a magic stemness markerBidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneityIntegration of Population-Level Genotype Data with Functional Annotation Reveals Over-Representation of Long Noncoding RNAs at Ovarian Cancer Susceptibility Loci.Knockdown of stem cell regulator Oct4A in ovarian cancer reveals cellular reprogramming associated with key regulators of cytoskeleton-extracellular matrix remodellingSalinomycin Promotes Anoikis and Decreases the CD44+/CD24- Stem-Like Population via Inhibition of STAT3 Activation in MDA-MB-231 CellsCytokine profiling of ascites at primary surgery identifies an interaction of tumor necrosis factor-α and interleukin-6 in predicting reduced progression-free survival in epithelial ovarian cancer.Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft modelsCoalition of Oct4A and β1 integrins in facilitating metastasis in ovarian cancer.STAT3 polymorphisms may predict an unfavorable response to first-line platinum-based therapy for women with advanced serous epithelial ovarian cancer.Notch and Wnt/β-catenin signaling pathway play important roles in activating liver cancer stem cells.Janus Kinase 1 Is Essential for Inflammatory Cytokine Signaling and Mammary Gland Remodeling.Unique proteome signature of post-chemotherapy ovarian cancer ascites-derived tumor cells.CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation.Ovarian cancer stem cells: still an elusive entity?Investigational therapies targeting signal transducer and activator of transcription 3 for the treatment of cancer.Existing drugs and their application in drug discovery targeting cancer stem cells.Recently identified drug resistance biomarkers in ovarian cancer.Cancer stem cells: Role in tumor growth, recurrence, metastasis, and treatment resistanceCrosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells.Chemical Proteomic Approaches Targeting Cancer Stem Cells: A Review of Current Literature.Annexin A1 is involved in the acquisition and maintenance of a stem cell-like/aggressive phenotype in prostate cancer cells with acquired resistance to zoledronic acid.Ruxolitinib sensitizes ovarian cancer to reduced dose Taxol, limits tumor growth and improves survival in immune competent mice.FGMD: A novel approach for functional gene module detection in cancer.The Many Facets of Metzincins and Their Endogenous Inhibitors: Perspectives on Ovarian Cancer Progression.Evidence for embryonic stem-like signature and epithelial-mesenchymal transition features in the spheroid cells derived from lung adenocarcinoma.Momelotinib decreased cancer stem cell associated tumor burden and prolonged disease-free remission period in a mouse model of human ovarian cancer.JAK2/STAT3 pathway as a therapeutic target in ovarian cancers.
P2860
Q26862078-AE5C5146-591F-41D0-BA91-3A935A66F331Q28066409-4C1ED63D-C725-4A6B-B889-87DDF453B194Q30275132-9D37A5BB-AC3D-4D66-8177-C395B8758F39Q33559947-EE6BF6D2-B1C9-4C2D-9853-AEE5FEAB99ECQ35830305-B4965AB4-0E2B-4EBB-A202-EE81FA774806Q35908928-FB4DC6A2-19C1-452F-A7E7-5BFBB5FDD49BQ35953034-2D0DC870-DCA4-4030-887A-35B7E9E45075Q36070842-F8A0EC65-9D3C-44AA-B7F4-B9CE8F941E43Q36761363-3B113EC4-686C-4222-A2DC-8F08125A1E78Q36905769-7EE42D7E-20A9-441D-AB6E-591019850521Q37122579-3BB5732F-2609-48DC-9CA3-14798B435CF4Q37137451-351BA5CE-A99D-478D-B07B-BF62AF6E06EEQ37629027-850E050C-B72D-4BB9-B2D9-FE7CA4388C77Q37713683-4945202A-82B1-4607-B22E-18B18810F6F4Q38369000-117AC5BF-383E-4130-A3A4-1F2E631B4FD5Q38543730-31F135D9-71AA-4776-AC19-AF283C440B29Q38741073-275B9ECF-2A04-4525-8A5B-56AD76DEE2ADQ38950219-C661A369-B7E5-431C-8C08-B126455DE1CBQ39299570-FDBC2F97-4524-4D65-A48C-39C36B2827C8Q41664062-DC07DE71-C164-4B66-B378-B994305AE2DEQ46416599-2497DB10-2EE1-494C-92DB-A92FAAAF944AQ47148643-A8A2590C-6767-4630-94B4-16B9FF69C51EQ47155833-A1AFBFB4-6736-40D7-A33F-4BD079C15111Q49375848-9AE270A0-0E7D-410F-A931-7121F9229738Q50482018-569F1A99-3188-44F4-9D1A-3582DCFC25EDQ54114902-4218E6E6-DF2A-4CB6-B818-BC3A9C39744BQ55269538-7100CA55-1040-4419-B739-C586EA7462E2
P2860
Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Inhibition of the JAK2/STAT3 p ...... ics and a reduced tumor burden
@ast
Inhibition of the JAK2/STAT3 p ...... ics and a reduced tumor burden
@en
type
label
Inhibition of the JAK2/STAT3 p ...... ics and a reduced tumor burden
@ast
Inhibition of the JAK2/STAT3 p ...... ics and a reduced tumor burden
@en
prefLabel
Inhibition of the JAK2/STAT3 p ...... ics and a reduced tumor burden
@ast
Inhibition of the JAK2/STAT3 p ...... ics and a reduced tumor burden
@en
P2093
P2860
P50
P356
P1433
P1476
Inhibition of the JAK2/STAT3 p ...... ics and a reduced tumor burden
@en
P2093
Hongjian Zhu
Jock K Findlay
Khalid Abubaker
Nuzhat Ahmed
Orla McNally
P2860
P2888
P356
10.1186/1471-2407-14-317
P407
P577
2014-05-06T00:00:00Z
P5875
P6179
1048764698