Splice-site mutations cause Rrp6-mediated nuclear retention of the unspliced RNAs and transcriptional down-regulation of the splicing-defective genes.
about
The RNA helicase DDX5/p68 is a key factor promoting c-fos expression at different levels from transcription to mRNA exportInhibition of U4 snRNA in human cells causes the stable retention of polyadenylated pre-mRNA in the nucleus.An Rrp6-like protein positively regulates noncoding RNA levels and DNA methylation in Arabidopsis.Nonsense-mediated decay as a terminating mechanism for antisense oligonucleotides.Global analysis of the nuclear processing of transcripts with unspliced U12-type introns by the exosome.Hidden treasures in unspliced EST data.The RNA polymerase II CTD coordinates transcription and RNA processing.The ribonuclease Dis3 is an essential regulator of the developmental transcriptome.Proofreading and spellchecking: a two-tier strategy for pre-mRNA splicing quality control.Coupling mRNA processing with transcription in time and space.Coupling and coordination in gene expression processes with pre-mRNA splicing.Evolution of the unspliced transcriptome.An Interaction between RRP6 and SU(VAR)3-9 Targets RRP6 to Heterochromatin and Contributes to Heterochromatin Maintenance in Drosophila melanogasterDis3- and exosome subunit-responsive 3' mRNA instability elementsRegulation of gene expression through inefficient splicing of U12-type intronsAlternative exon definition events control the choice between nuclear retention and cytoplasmic export of U11/U12-65K mRNA.Mitosis in vertebrates: the G2/M and M/A transitions and their associated checkpoints.Where splicing joins chromatin.mRNA quality control goes transcriptional.Integration of mRNP formation and export.Regulation of conditional gene expression by coupled transcription repression and RNA degradation.RNA biology of disease-associated microsatellite repeat expansions.The Conserved RNA Binding Cyclophilin, Rct1, Regulates Small RNA Biogenesis and Splicing Independent of Heterochromatin Assembly.Splicing-coupled 3' end formation requires a terminal splice acceptor site, but not intron excision.Rrp6 is recruited to transcribed genes and accompanies the spliced mRNA to the nuclear pore.Co-transcriptional degradation of aberrant pre-mRNA by Xrn2.Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay.
P2860
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P2860
Splice-site mutations cause Rrp6-mediated nuclear retention of the unspliced RNAs and transcriptional down-regulation of the splicing-defective genes.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Splice-site mutations cause Rr ...... the splicing-defective genes.
@ast
Splice-site mutations cause Rr ...... the splicing-defective genes.
@en
type
label
Splice-site mutations cause Rr ...... the splicing-defective genes.
@ast
Splice-site mutations cause Rr ...... the splicing-defective genes.
@en
prefLabel
Splice-site mutations cause Rr ...... the splicing-defective genes.
@ast
Splice-site mutations cause Rr ...... the splicing-defective genes.
@en
P2093
P2860
P1433
P1476
Splice-site mutations cause Rr ...... the splicing-defective genes.
@en
P2093
Andrea B Eberle
Niclas Gimber
Roger Helbig
Viktoria Hessle
Widad Dantoft
P2860
P304
P356
10.1371/JOURNAL.PONE.0011540
P407
P577
2010-07-12T00:00:00Z