Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormones
about
Adrenal Mitochondria and Steroidogenesis: From Individual Proteins to Functional Protein AssembliesRole of Protein Phosphorylation and Tyrosine Phosphatases in the Adrenal Regulation of Steroid Synthesis and Mitochondrial FunctionMitochondrial function and regulation of macrophage sterol metabolism and inflammatory responsesEvolutionary origin of the mitochondrial cholesterol transport machinery reveals a universal mechanism of steroid hormone biosynthesis in animalsACTH Action on StAR BiologyTranslocator protein-mediated pharmacology of cholesterol transport and steroidogenesisBinding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterolsStAR enhances transcription of genes encoding the mitochondrial proteases involved in its own degradationATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.Mitochondrial fusion and ERK activity regulate steroidogenic acute regulatory protein localization in mitochondriaEstradiol modulates translocator protein (TSPO) and steroid acute regulatory protein (StAR) via protein kinase A (PKA) signaling in hypothalamic astrocytesProtein modifications regulate the role of 14-3-3γ adaptor protein in cAMP-induced steroidogenesis in MA-10 Leydig cells.Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production.Neurosteroid biosynthesis downregulation and changes in GABAA receptor subunit composition: A biomarker axis in stress-induced cognitive and emotional impairment.Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthaseSteroidogenesis in MA-10 mouse Leydig cells is altered via fatty acid import into the mitochondria.Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation.Carbenoxolone induces permeability transition pore opening in rat mitochondria via the translocator protein TSPO and connexin43.Evolving understanding of translocator protein 18 kDa (TSPO)Role of the steroidogenic acute regulatory protein in health and disease.Acute effects of hexabromocyclododecane on Leydig cell cyclic nucleotide signaling and steroidogenesis in vitro.Drug ligand-induced activation of translocator protein (TSPO) stimulates steroid production by aged brown Norway rat Leydig cellsMitochondrial protein ATPase family, AAA domain containing 3A correlates with radioresistance in glioblastoma.TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood.Recurrent De Novo and Biallelic Variation of ATAD3A, Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes.The role of PBR/TSPO in steroid biosynthesis challenged.Direct modulation of the outer mitochondrial membrane channel, voltage-dependent anion channel 1 (VDAC1) by cannabidiol: a novel mechanism for cannabinoid-induced cell deathTranslocator Protein 18 kDa (TSPO): An Old Protein with New Functions?Regulation of adrenocortical steroid hormone production by RhoA-diaphanous 1 signaling and the cytoskeleton.Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function.Translocator protein (18 kDa): an update on its function in steroidogenesis.Plasma Membrane Origin of the Steroidogenic Pool of Cholesterol Used in Hormone-induced Acute Steroid Formation in Leydig Cells.Revisiting trends on mitochondrial mega-channels for the import of proteins and nucleic acids.A brief history of the search for the protein(s) involved in the acute regulation of steroidogenesis.A single cell level measurement of StAR expression and activity in adrenal cells.Translocator protein (TSPO) ligands for the diagnosis or treatment of neurodegenerative diseases: a patent review (2010-2015; part 1).Mitochondrial Membrane Dynamics and Inherited Optic Neuropathies.Increased steroidogenesis promotes early-onset and severe vision loss in females with OPA1 dominant optic atrophy.Structure-to-function relationships of bacterial translocator protein (TSPO): a focus on Pseudomonas.ACBD2/ECI2-Mediated Peroxisome-Mitochondria Interactions in Leydig Cell Steroid Biosynthesis
P2860
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P2860
Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormones
description
2012 nî lūn-bûn
@nan
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Identification of a dynamic mi ...... metabolism to steroid hormones
@ast
Identification of a dynamic mi ...... metabolism to steroid hormones
@en
type
label
Identification of a dynamic mi ...... metabolism to steroid hormones
@ast
Identification of a dynamic mi ...... metabolism to steroid hormones
@en
prefLabel
Identification of a dynamic mi ...... metabolism to steroid hormones
@ast
Identification of a dynamic mi ...... metabolism to steroid hormones
@en
P2093
P2860
P356
P1476
Identification of a dynamic mi ...... metabolism to steroid hormones
@en
P2093
Andrew S Midzak
Georges Rammouz
Jinjiang Fan
Josip Blonder
Malena B Rone
Sathvika Jagannathan
Timothy Veenstra
Xiaoying Ye
P2860
P304
P356
10.1210/ME.2012-1159
P577
2012-09-12T00:00:00Z