The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis.
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Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapyAn outline of necrosome triggersCell apoptosis, autophagy and necroptosis in osteosarcoma treatmentCalpain: a molecule to induce AIF-mediated necroptosis in RGC-5 following elevated hydrostatic pressureApoptosis, autophagy, necroptosis, and cancer metastasisReceptor interacting protein 3-induced RGC-5 cell necroptosis following oxygen glucose deprivation.Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death.Hesperidin from Citrus seed induces human hepatocellular carcinoma HepG2 cell apoptosis via both mitochondrial and death receptor pathwaysN-end rule pathway inhibition assists colon tumor regression via necroptosis.Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species.Alternol, a natural compound, exerts an anti-tumour effect on osteosarcoma by modulating of STAT3 and ROS/MAPK signalling pathways.Anti-inflammatory properties of shikonin contribute to improved early-stage diabetic retinopathy.Research progress on the multidrug resistance mechanisms of osteosarcoma chemotherapy and reversal.The importance of being dead: cell death mechanisms assessment in anti-sarcoma therapy.Necroptosis: A new way of dying?Cancer and necroptosis: friend or foe?RIP1K and RIP3K provoked by shikonin induce cell cycle arrest in the triple negative breast cancer cell line, MDA-MB-468: necroptosis as a desperate programmed suicide pathway.Shikonin inhibits invasiveness of osteosarcoma through MMP13 suppression.Phospho-ΔNp63α-responsive microRNAs contribute to the regulation of necroptosis in squamous cell carcinoma upon cisplatin exposure.Shikonin inhibits the cell viability, adhesion, invasion and migration of the human gastric cancer cell line MGC-803 via the Toll-like receptor 2/nuclear factor-kappa B pathway.Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells.Combination simvastatin and metformin induces G1-phase cell cycle arrest and Ripk1- and Ripk3-dependent necrosis in C4-2B osseous metastatic castration-resistant prostate cancer cells.Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis.Natural Compounds As Modulators of Non-apoptotic Cell Death in Cancer Cells.Necroptosis in cancer: An angel or a demon?Reassessing the role of NAD as a prosurvival factor.Exploitation of necroptosis for treatment of caspase-compromised cancers.Naphthoquinones: A continuing source for discovery of therapeutic antineoplastic agents.Shikonin induces glioma cell necroptosis in vitro by ROS overproduction and promoting RIP1/RIP3 necrosome formation.BIOSSES: a semantic sentence similarity estimation system for the biomedical domain.Sarcoma-Targeting Peptide-Decorated Polypeptide Nanogel Intracellularly Delivers Shikonin for Upregulated Osteosarcoma Necroptosis and Diminished Pulmonary Metastasis.Time to tame necroptosis - viable combat against chemo resistant oral cancer cells.
P2860
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P2860
The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis.
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The anti-tumor effect of shiko ...... nd RIP3 dependent necroptosis.
@ast
The anti-tumor effect of shiko ...... nd RIP3 dependent necroptosis.
@en
type
label
The anti-tumor effect of shiko ...... nd RIP3 dependent necroptosis.
@ast
The anti-tumor effect of shiko ...... nd RIP3 dependent necroptosis.
@en
prefLabel
The anti-tumor effect of shiko ...... nd RIP3 dependent necroptosis.
@ast
The anti-tumor effect of shiko ...... nd RIP3 dependent necroptosis.
@en
P2093
P2860
P356
P1433
P1476
The anti-tumor effect of shiko ...... nd RIP3 dependent necroptosis.
@en
P2093
Biyong Deng
Dongqing Zuo
Liancheng Shan
Yingqi Hua
Yuxin Liao
Zhengdong Cai
Zhuoying Wang
P2860
P2888
P356
10.1186/1471-2407-13-580
P407
P577
2013-12-06T00:00:00Z
P5875
P6179
1049852515