Nucleic acid evolution and minimization by nonhomologous random recombination.
about
Directed evolution of protein enzymes using nonhomologous random recombinationIdentification of a 14mer RNA that recognizes and binds flavin mononucleotide with high affinity.Methods for Improving Aptamer Binding AffinityProbing the SELEX process with next-generation sequencingApplication of the "codon-shuffling" method. Synthesis and selection of de novo proteins as antibacterials.Unbiased selection of localization elements reveals cis-acting determinants of mRNA bud localization in Saccharomyces cerevisiae.Identification of eukaryotic promoter regulatory elements using nonhomologous random recombination.Discovery of a mRNA mitochondrial localization element in Saccharomyces cerevisiae by nonhomologous random recombination and in vivo selectionSelecting folded proteins from a library of secondary structural elements.Enhanced functional potential of nucleic acid aptamer libraries patterned to increase secondary structureLaser ablation-based one-step generation and bio-functionalization of gold nanoparticles conjugated with aptamers.Discovery of an entropically-driven small molecule streptavidin binder from nucleic acid-encoded libraries.Selection of the simplest RNA that binds isoleucineImproving aptamer selection efficiency through volume dilution, magnetic concentration, and continuous washing in microfluidic channelsDevelopment of a fraction collection approach in capillary electrophoresis SELEX for aptamer selection.Single-Round Patterned DNA Library Microarray Aptamer Lead Identification.Selection of DNA nanoparticles with preferential binding to aggregated protein target.Synthetic shuffling and in vitro selection reveal the rugged adaptive fitness landscape of a kinase ribozyme.Expansion of the aptamer library from a "natural soup" to an "unnatural soup".Sex in a test tube: testing the benefits of in vitro recombination.A DNA aptamer to c-Met inhibits cancer cell migration.Ribozyme motif structure mapped using random recombination and selection.Conjugation of two RNA aptamers improves binding affinity to AML1 Runt domain.Key Aspects of Nucleic Acid Library Design for in Vitro Selection.Creating protein biocatalysts as tools for future industrial applications
P2860
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P2860
Nucleic acid evolution and minimization by nonhomologous random recombination.
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Nucleic acid evolution and minimization by nonhomologous random recombination.
@ast
Nucleic acid evolution and minimization by nonhomologous random recombination.
@en
type
label
Nucleic acid evolution and minimization by nonhomologous random recombination.
@ast
Nucleic acid evolution and minimization by nonhomologous random recombination.
@en
prefLabel
Nucleic acid evolution and minimization by nonhomologous random recombination.
@ast
Nucleic acid evolution and minimization by nonhomologous random recombination.
@en
P2093
P2860
P356
P1433
P1476
Nucleic acid evolution and minimization by nonhomologous random recombination.
@en
P2093
Brian V Le
David R Liu
Joshua A Bittker
P2860
P2888
P304
P356
10.1038/NBT736
P577
2002-09-09T00:00:00Z