Identification of CXCR4 domains that support coreceptor and chemokine receptor functions
about
CCR8 on human thymocytes functions as a human immunodeficiency virus type 1 coreceptor.Molecular recognition of CXCR4 by a dual tropic HIV-1 gp120 V3 loopStructures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonistsHuman immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinaseApoptosis of uninfected cells induced by HIV envelope glycoproteinsStructural Basis of CXCR4 Sulfotyrosine Recognition by the Chemokine SDF-1/CXCL12Bioinformatic analysis of HIV-1 entry and pathogenesis.Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptorMorphine increases brain levels of ferritin heavy chain leading to inhibition of CXCR4-mediated survival signaling in neuronsElucidating a key component of cancer metastasis: CXCL12 (SDF-1α) binding to CXCR4.Actin cytoskeletal reorganizations and coreceptor-mediated activation of rac during human immunodeficiency virus-induced cell fusionUnique ligand binding sites on CXCR4 probed by a chemical biology approach: implications for the design of selective human immunodeficiency virus type 1 inhibitors.Control of cell migration in the development of the posterior lateral line: antagonistic interactions between the chemokine receptors CXCR4 and CXCR7/RDC1.The HIV envelope but not VSV glycoprotein is capable of mediating HIV latent infection of resting CD4 T cellsSequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: soluble CD4 activates Env for coreceptor-dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120.Novel peptides based on HIV-1 gp120 sequence with homology to chemokines inhibit HIV infection in cell culture.N-linked glycosylation of CXCR4 masks coreceptor function for CCR5-dependent human immunodeficiency virus type 1 isolates.Simian immunodeficiency viruses of diverse origin can use CXCR4 as a coreceptor for entry into human cellsMolecular basis for cell tropism of CXCR4-dependent human immunodeficiency virus type 1 isolatesAntigenically distinct conformations of CXCR4.Adaptive mutations in the V3 loop of gp120 enhance fusogenicity of human immunodeficiency virus type 1 and enable use of a CCR5 coreceptor that lacks the amino-terminal sulfated regionCyanovirin-N, a potent human immunodeficiency virus-inactivating protein, blocks both CD4-dependent and CD4-independent binding of soluble gp120 (sgp120) to target cells, inhibits sCD4-induced binding of sgp120 to cell-associated CXCR4, and dissociaDistinct functional sites for human immunodeficiency virus type 1 and stromal cell-derived factor 1alpha on CXCR4 transmembrane helical domainsDistinct molecular pathways to X4 tropism for a V3-truncated human immunodeficiency virus type 1 lead to differential coreceptor interactions and sensitivity to a CXCR4 antagonist.Defining differential genetic signatures in CXCR4- and the CCR5-utilizing HIV-1 co-linear sequences.Impact of constitutional polymorphisms in VCAM1 and CD44 on CD34+ cell collection yield after administration of granulocyte colony-stimulating factor to healthy donors.Identification of gp120 binding sites on CXCR4 by using CD4-independent human immunodeficiency virus type 2 Env proteins.Signal transmission through the CXC chemokine receptor 4 (CXCR4) transmembrane helices.Fragment-based optimization of small molecule CXCL12 inhibitors for antagonizing the CXCL12/CXCR4 interaction.An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes.HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropismQuantitative analysis of the processes and signaling events involved in early HIV-1 infection of T cells.A biosensor assay for studying ligand-membrane receptor interactions: binding of antibodies and HIV-1 Env to chemokine receptorsThe CXC chemokine receptor 4 ligands ubiquitin and stromal cell-derived factor-1α function through distinct receptor interactions.Structural determinants of ubiquitin-CXC chemokine receptor 4 interaction.Inhibition of metastasis of rhabdomyosarcoma by a novel neutralizing antibody to CXC chemokine receptor-4.Rapamycin reduces CCR5 density levels on CD4 T cells, and this effect results in potentiation of enfuvirtide (T-20) against R5 strains of human immunodeficiency virus type 1 in vitro.The trinity of the cortical actin in the initiation of HIV-1 infectionSelectivity in the Use of Gi/o Proteins Is Determined by the DRF Motif in CXCR6 and Is Cell-Type Specific.A novel synthetic bivalent ligand to probe chemokine receptor CXCR4 dimerization and inhibit HIV-1 entry.
P2860
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P2860
Identification of CXCR4 domains that support coreceptor and chemokine receptor functions
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Identification of CXCR4 domains that support coreceptor and chemokine receptor functions
@ast
Identification of CXCR4 domains that support coreceptor and chemokine receptor functions
@en
type
label
Identification of CXCR4 domains that support coreceptor and chemokine receptor functions
@ast
Identification of CXCR4 domains that support coreceptor and chemokine receptor functions
@en
prefLabel
Identification of CXCR4 domains that support coreceptor and chemokine receptor functions
@ast
Identification of CXCR4 domains that support coreceptor and chemokine receptor functions
@en
P2093
P2860
P1433
P1476
Identification of CXCR4 domains that support coreceptor and chemokine receptor functions
@en
P2093
B J Doranz
J D Turner
J F Berson
M J Orsini
S C Peiper
T L Hoffman
P2860
P304
P577
1999-04-01T00:00:00Z