Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.
about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesMoving forward with reactive oxygen species involvement in antimicrobial lethalityThe Cell Killing Mechanisms of HydroxyureaYet another way that phage λ manipulates its Escherichia coli host: λrexB is involved in the lysogenic-lytic switchOxidation of the guanine nucleotide pool underlies cell death by bactericidal antibioticsSynthetic circuit identifies subpopulations with sustained memory of DNA damageRole of cysteines in the stability and DNA-binding activity of the hypochlorite-specific transcription factor HypTMethyl-hydroxylamine as an efficacious antibacterial agent that targets the ribonucleotide reductase enzymeBiochemical Characterization of the Split Class II Ribonucleotide Reductase from Pseudomonas aeruginosaCentral role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria.Antibiotics induce redox-related physiological alterations as part of their lethality.Ribonucleotide reductase metallocofactor: assembly, maintenance and inhibition.Resolution of gene regulatory conflicts caused by combinations of antibiotics.How antibiotics kill bacteria: from targets to networksIron homeostasis affects antibiotic-mediated cell death in Pseudomonas species.A toxin-antitoxin module in Bacillus subtilis can both mitigate and amplify effects of lethal stress.Host-guest chemistry of the peptidoglycanDiscovery of antimicrobial ribonucleotide reductase inhibitors by screening in microwell formatSigma S-dependent antioxidant defense protects stationary-phase Escherichia coli against the bactericidal antibiotic gentamicin.Sinorhizobium meliloti requires a cobalamin-dependent ribonucleotide reductase for symbiosis with its plant host.The Escherichia coli GTPase ObgE modulates hydroxyl radical levels in response to DNA replication fork arrest.Reactive oxygen species and the bacterial response to lethal stressSelenoprotein H suppresses cellular senescence through genome maintenance and redox regulationProtein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymerase.Small-molecule inhibitors suppress the expression of both type III secretion and amylovoran biosynthesis genes in Erwinia amylovora.Ribosomal elongation factor 4 promotes cell death associated with lethal stressGeneration of reactive oxygen species by lethal attacks from competing microbes.Alpha-synuclein functions in the nucleus to protect against hydroxyurea-induced replication stress in yeast.Diagnosing oxidative stress in bacteria: not as easy as you might thinkEvolutionary genome engineering using a restriction-modification system.The SOS response is permitted in Escherichia coli strains deficient in the expression of the mazEF pathway.Proteasome Accessory Factor C (pafC) Is a novel gene Involved in Mycobacterium Intrinsic Resistance to broad-spectrum antibiotics--Fluoroquinolones.Whole genome sequencing of penicillin-resistant Streptococcus pneumoniae reveals mutations in penicillin-binding proteins and in a putative iron permease.The rcbA gene product reduces spontaneous and induced chromosome breaks in Escherichia coli.Resveratrol Antagonizes Antimicrobial Lethality and Stimulates Recovery of Bacterial Mutants.The aminoglycoside antibiotic kanamycin damages DNA bases in Escherichia coli: caffeine potentiates the DNA-damaging effects of kanamycin while suppressing cell killing by ciprofloxacin in Escherichia coli and Bacillus anthracis.Rapid killing of Acinetobacter baumannii by polymyxins is mediated by a hydroxyl radical death pathwayInhibitors of reactive oxygen species accumulation delay and/or reduce the lethality of several antistaphylococcal agents.High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance.YihE kinase is a central regulator of programmed cell death in bacteria
P2860
Q24289511-C8C22F8B-DD9E-4CA8-8BEB-5277A1B22605Q26995546-937EEDDF-3723-48CF-8471-9EE5D75EBCA7Q28080250-89F5A812-469A-4DE8-8AD8-F86D1995E3DCQ28082783-4AFEAE57-9644-424C-A471-5F4062A747B7Q28264943-3218588E-C420-4746-9A69-FEA5ECE26DBDQ28306330-6FE003F0-27E0-46B0-A541-7150724046A1Q28534166-FE4204EC-6FC7-47A6-9825-8EC797F388E5Q28544447-074FC613-0947-4F41-9E82-55B2D9157347Q28546909-2462380A-0DD1-4B44-BDF2-5D7A360E0AB8Q31151284-FCB4960D-9CC7-480B-82C3-EA7CB5530F26Q33665248-929DD3D6-A7DD-4D94-AFEF-28036C801BA4Q33699869-FB15796A-45BE-4AA3-B5B9-E051596881F1Q33906373-61EA9E2F-E52B-43AA-8EDC-7A4B45B7B914Q33958766-321ECEE4-C838-4604-9546-FBC606F661EAQ33991305-938A2C70-08B1-482F-8EF2-637D15D1F2B7Q34012810-46DDD71C-2B34-43A1-9678-283E2A018687Q34013593-19B44410-D449-4DB7-9149-BFDC3B25FE93Q34292119-5DF825C7-2861-41BD-8ADE-080CBD706882Q34299166-0BFA1A91-32C5-4E16-9A6A-D4434F37512AQ34302045-5FD45312-BB93-4D8E-AF43-EFF5D3B54DC5Q34366109-B624EC4C-F5B1-46C4-B04F-D2AFEDEE80A2Q34624207-4068B7BA-5FC1-4951-892C-FAF10C44064BQ34634340-E08C37E2-FE32-49E3-A94F-B2C385E96A4AQ34723636-D0C1756F-BB15-4F5C-B78E-5519A905C598Q34893460-01B4DA57-3A90-4DC6-B7E5-6831A85B5259Q35072151-5CEC5A93-7F1D-4A5A-BBF1-990AA22B7A94Q35128847-7CC93642-7B32-4BDB-91CE-E01AEAB24FDBQ35155985-127BEFB6-A74B-4E74-BCFB-814E8F70F228Q35235708-F1EEB279-F409-44D8-9226-4FF6C4A95138Q35468394-84A6E611-D5AA-4D21-9553-6C516A4CC472Q35485080-673619AA-C7C5-484D-B567-FD6B44D7B198Q35814202-ADDD05D0-4D9D-4573-B345-96D3F0E595E6Q35907639-5E346878-7094-4463-AB2F-B5D87B1DD744Q35942777-8DA1076A-3EB3-4770-9108-531B08089C11Q35979673-B46565C4-9DC4-4F36-B62A-DD0F6242F264Q36018582-586531A8-F86C-41F3-BF93-4C9460915AB4Q36364121-7C1C0039-A884-472D-A29D-434C13FC545BQ36364252-8195EBDD-9413-41D0-951B-422BA995E6EEQ36410455-A09F9A5E-78C0-48F0-A652-127979A76826Q36674733-77A768A9-E308-444E-AF41-45A08560A6F8
P2860
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.
@ast
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.
@en
type
label
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.
@ast
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.
@en
prefLabel
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.
@ast
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.
@en
P2093
P2860
P1433
P1476
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli
@en
P2093
Bryan W Davies
James J Collins
Jonathan A Winkler
Lyle A Simmons
Michael A Kohanski
P2860
P304
P356
10.1016/J.MOLCEL.2009.11.024
P50
P577
2009-12-01T00:00:00Z