Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing.
about
Fitness Landscapes of Functional RNAsOpportunities in the design and application of RNA for gene expression controlProbing the limits of aptamer affinity with a microfluidic SELEX platformScreening of peptide libraries against protective antigen of Bacillus anthracis in a disposable microfluidic cartridgeDiscovering aptamers by cell-SELEX against human soluble growth factors ectopically expressed on yeast cell surfaceGalaxy Workflows for Web-based Bioinformatics Analysis of Aptamer High-throughput Sequencing DataProbing the SELEX process with next-generation sequencingIn vitro RNA SELEX for the generation of chemically-optimized therapeutic RNA drugsAcousto-microfluidics for screening of ssDNA aptamer.Toward integrated molecular diagnostic system (i MDx): principles and applications.Micro total analysis systems for cell biology and biochemical assaysAptamer in bioanalytical applications.Analyzing HT-SELEX data with the Galaxy Project tools--A web based bioinformatics platform for biomedical research.Acyclic identification of aptamers for human alpha-thrombin using over-represented libraries and deep sequencing.MPBind: a Meta-motif-based statistical framework and pipeline to Predict Binding potential of SELEX-derived aptamers.Isolation and optimization of murine IL-10 receptor blocking oligonucleotide aptamers using high-throughput sequencing.Microfluidic approaches to rapid and efficient aptamer selection.Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selectionNew Technologies Provide Quantum Changes in the Scale, Speed, and Success of SELEX Methods and Aptamer Characterization.Single-round, multiplexed antibody mimetic design through mRNA display.Multiplexed microcolumn-based process for efficient selection of RNA aptamers.Aptamer-based cell imaging reagents capable of fluorescence switching.Array-based discovery of aptamer pairsDevelopment of an efficient targeted cell-SELEX procedure for DNA aptamer reagents.Tracking the emergence of high affinity aptamers for rhVEGF165 during capillary electrophoresis-systematic evolution of ligands by exponential enrichment using high throughput sequencing.Next-generation sequencing reveals how RNA catalysts evolve from random space.Quantitative selection and parallel characterization of aptamers.RAPID-SELEX for RNA aptamersPharmacokinetic characterization of an RNA aptamer against osteopontin and demonstration of in vivo efficacy in reversing growth of human breast cancer cellsFASTAptamer: A Bioinformatic Toolkit for High-throughput Sequence Analysis of Combinatorial Selections.Deep mutational scanning: assessing protein function on a massive scale.Improving aptamer selection efficiency through volume dilution, magnetic concentration, and continuous washing in microfluidic channelsSingle-step selection of bivalent aptamers validated by comparison with SELEX using high-throughput sequencingAdvancing small-molecule-based chemical biology with next-generation sequencing technologies.A method for selecting structure-switching aptamers applied to a colorimetric gold nanoparticle assaySelection of LNA-containing DNA aptamers against recombinant human CD73.Hi-Fi SELEX: A High-Fidelity Digital-PCR Based Therapeutic Aptamer Discovery Platform.Large scale analysis of the mutational landscape in HT-SELEX improves aptamer discoveryIdentifying high-affinity aptamer ligands with defined cross-reactivity using high-throughput guided systematic evolution of ligands by exponential enrichmentSingle-Round Patterned DNA Library Microarray Aptamer Lead Identification.
P2860
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P2860
Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Quantitative selection of DNA ...... nd high-throughput sequencing.
@ast
Quantitative selection of DNA ...... nd high-throughput sequencing.
@en
type
label
Quantitative selection of DNA ...... nd high-throughput sequencing.
@ast
Quantitative selection of DNA ...... nd high-throughput sequencing.
@en
prefLabel
Quantitative selection of DNA ...... nd high-throughput sequencing.
@ast
Quantitative selection of DNA ...... nd high-throughput sequencing.
@en
P2093
P2860
P356
P1476
Quantitative selection of DNA ...... nd high-throughput sequencing.
@en
P2093
Andrew T Csordas
James A Thomson
Minseon Cho
Ron Stewart
P2860
P304
15373-15378
P356
10.1073/PNAS.1009331107
P407
P50
P577
2010-08-12T00:00:00Z