The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease.
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Stem cell transplantation therapy in Parkinson's diseaseIntrastriatal Grafting of Chromospheres: Survival and Functional Effects in the 6-OHDA Rat Model of Parkinson's DiseaseAutologous mesenchymal stem cell-derived dopaminergic neurons function in parkinsonian macaques.Autologous transplantation of GDNF-expressing mesenchymal stem cells protects against MPTP-induced damage in cynomolgus monkeysEfficient generation of hPSC-derived midbrain dopaminergic neurons in a fully defined, scalable, 3D biomaterial platform.Designer receptors: therapeutic adjuncts to cell replacement therapy in Parkinson's disease.Oct4-induced reprogramming is required for adult brain neural stem cell differentiation into midbrain dopaminergic neuronsProspect of cell therapy for Parkinson's disease.Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid.Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain.Generation of induced neurons via direct conversion in vivo.Neuronal-like differentiation of bone marrow-derived mesenchymal stem cells induced by striatal extracts from a rat model of Parkinson's diseaseTransplanting intact donor tissue enhances dopamine cell survival and the predictability of motor improvements in a rat model of Parkinson's diseaseHuman ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease.Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonismTranscriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors.Sorting the wheat from the chaff in dopamine neuron-based cell therapies.Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease.Dopamine cell transplantation in Parkinson's disease: challenge and perspective.Transdifferentiation of Fibroblasts by Defined Factors.Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation.Anatomy of Graft-induced Dyskinesias: Circuit Remodeling in the Parkinsonian StriatumTransplantation site influences the phenotypic differentiation of dopamine neurons in ventral mesencephalic grafts in Parkinsonian rats.Drug discovery in Parkinson's disease-Update and developments in the use of cellular models.Amelioration of non-motor dysfunctions after transplantation of human dopamine neurons in a model of Parkinson's diseaseNogo-A Neutralization Improves Graft Function in a Rat Model of Parkinson's Disease.FGF9-Pitx2-FGF10 signaling controls cecal formation in mice.Recovery from experimental parkinsonism by semaphorin-guided axonal growth of grafted dopamine neurons.Functions of the nigrostriatal dopaminergic synapse and the use of neurotransplantation in Parkinson's disease.Cell-based therapies for Parkinson's disease.Dopaminergic axon guidance: which makes what?Directed midbrain and spinal cord neurogenesis from pluripotent stem cells to model development and disease in a dish.Molecular mechanisms of dopaminergic subset specification: fundamental aspects and clinical perspectives.Modeling physiological and pathological human neurogenesis in the dish.The potential of alternate sources of cells for neural grafting in Parkinson's and Huntington's disease.A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells.Optogenetic inactivation of the subthalamic nucleus improves forelimb akinesia in a rat model of Parkinson disease.Historical perspective of cell transplantation in Parkinson's disease.Anodal Transcranial Direct Current Stimulation Enhances Survival and Integration of Dopaminergic Cell Transplants in a Rat Parkinson Model.Lentivirus-mediated delivery of sonic hedgehog into the striatum stimulates neuroregeneration in a rat model of Parkinson disease.
P2860
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P2860
The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The A9 dopamine neuron compone ...... model of Parkinson's disease.
@ast
The A9 dopamine neuron compone ...... model of Parkinson's disease.
@en
type
label
The A9 dopamine neuron compone ...... model of Parkinson's disease.
@ast
The A9 dopamine neuron compone ...... model of Parkinson's disease.
@en
prefLabel
The A9 dopamine neuron compone ...... model of Parkinson's disease.
@ast
The A9 dopamine neuron compone ...... model of Parkinson's disease.
@en
P2093
P2860
P50
P356
P1433
P1476
The A9 dopamine neuron compone ...... model of Parkinson's disease.
@en
P2093
Deniz Kirik
Lachlan H Thompson
P2860
P304
P356
10.1093/BRAIN/AWP328
P407
P577
2010-01-31T00:00:00Z