Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications.
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Transcription Blockage Leads to New BeginningsMutual interdependence of splicing and transcription elongationGetting up to speed with transcription elongation by RNA polymerase IIWidespread intron retention in mammals functionally tunes transcriptomesOn the Molecular Evolution of Leptin, Leptin Receptor, and EndospaninStatistical modeling of isoform splicing dynamics from RNA-seq time series data.Wide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo.Relationship between epigenetic changes in Wnt antagonists and acute leukemiaGenome-wide binding of MBD2 reveals strong preference for highly methylated loci4sUDRB-seq: measuring genomewide transcriptional elongation rates and initiation frequencies within cells.Pre-mRNA splicing is facilitated by an optimal RNA polymerase II elongation rate.Mathematical model of the Tat-Rev regulation of HIV-1 replication in an activated cell predicts the existence of oscillatory dynamics in the synthesis of viral componentsConsidering the kinetics of mRNA synthesis in the analysis of the genome and epigenome reveals determinants of co-transcriptional splicing.DNA repair and recovery of RNA synthesis following exposure to ultraviolet light are delayed in long genes.Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.Why Selection Might Be Stronger When Populations Are Small: Intron Size and Density Predict within and between-Species Usage of Exonic Splice Associated cis-Motifs.Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus.Introns and gene expression: cellular constraints, transcriptional regulation, and evolutionary consequences.Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos.Defective histone supply causes changes in RNA polymerase II elongation rate and cotranscriptional pre-mRNA splicingIdentifying transcription start sites and active enhancer elements using BruUV-seq.Mapping Human Pluripotent-to-Cardiomyocyte Differentiation: Methylomes, Transcriptomes, and Exon DNA Methylation "Memories".Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes.Capturing the dynamic nascent transcriptome during acute cellular responses: The serum responseRNA Polymerase II cluster dynamics predict mRNA output in living cellsComprehensive RNA Polymerase II Interactomes Reveal Distinct and Varied Roles for Each Phospho-CTD Residue.Intron Length Coevolution across Mammalian GenomesTranscriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism.The regulatory mechanisms of intragenic DNA methylation.The upstreams and downstreams of H3K79 methylation by DOT1L.Transcriptional Elongation Regulator 1 Affects Transcription and Splicing of Genes Associated with Cellular Morphology and Cytoskeleton Dynamics and Is Required for Neurite Outgrowth in Neuroblastoma Cells and Primary Neuronal Cultures.DNA demethylation induces SALL4 gene re-expression in subgroups of hepatocellular carcinoma associated with Hepatitis B or C virus infection.Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-βFactors affecting the persistence of drug-induced reprogramming of the cancer methylome.Coupling of RNA Polymerase II Transcription Elongation with Pre-mRNA Splicing.Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition.Genome stability versus transcript diversity.Cotranscriptional histone H2B monoubiquitylation is tightly coupled with RNA polymerase II elongation rate.Perfect timing: splicing and transcription rates in living cells.
P2860
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P2860
Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications.
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Rate of elongation by RNA poly ...... and epigenetic modifications.
@ast
Rate of elongation by RNA poly ...... and epigenetic modifications.
@en
type
label
Rate of elongation by RNA poly ...... and epigenetic modifications.
@ast
Rate of elongation by RNA poly ...... and epigenetic modifications.
@en
prefLabel
Rate of elongation by RNA poly ...... and epigenetic modifications.
@ast
Rate of elongation by RNA poly ...... and epigenetic modifications.
@en
P2093
P2860
P356
P1433
P1476
Rate of elongation by RNA poly ...... and epigenetic modifications.
@en
P2093
Artur Veloso
Benjamin Biewen
Brian Magnuson
Killeen S Kirkconnell
Mats Ljungman
Michelle T Paulsen
Thomas E Wilson
P2860
P304
P356
10.1101/GR.171405.113
P577
2014-04-08T00:00:00Z