Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR - Wikidata - wikimedia - TriplyDB

Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR

Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR

http://www.wikidata.org/entity/Q33661920

about

The Promise and Challenge of Therapeutic MicroRNA Silencing in Diabetes and Metabolic Diseases The effects of microRNA on the absorption, distribution, metabolism and excretion of drugs Noncoding RNAs: key molecules in understanding and treating pain miR-17-92 cluster targets phosphatase and tensin homology and Ikaros Family Zinc Finger 4 to promote TH17-mediated inflammation MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo MicroRNA-management of lipoprotein homeostasis.Integrative analysis of differential miRNA and functional study of miR-21 by seed-targeting inhibition in multiple myeloma cells in response to berberine.Control of very low-density lipoprotein secretion by N-ethylmaleimide-sensitive factor and miR-33 Development of microRNA therapeutics is coming of age.Epigenetic regulation of cholesterol homeostasis.microRNAs and HDL life cycle.Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice MicroRNAs: a connection between cholesterol metabolism and neurodegeneration.Prospects for Therapeutic Targeting of MicroRNAs in Human Immunological Diseases.MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids.Inhibition of Gastric Tumor Cell Growth Using Seed-targeting LNA as Specific, Long-lasting MicroRNA Inhibitors.Cooperative target mRNA destabilization and translation inhibition by miR-58 microRNA family in C. elegans.microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain Therapeutic Inhibition of miR-33 Promotes Fatty Acid Oxidation but Does Not Ameliorate Metabolic Dysfunction in Diet-Induced Obesity.MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels.The miR-130 family promotes cell migration and invasion in bladder cancer through FAK and Akt phosphorylation by regulating PTEN.MicroRNA Regulation of Atherosclerosis.SREBP-1c/MicroRNA 33b Genomic Loci Control Adipocyte Differentiation.Micro-RNAs and High-Density Lipoprotein Metabolism.microRNA regulation of lipoprotein metabolism.How Gene Networks Can Uncover Novel CVD Players.microRNAs in lipoprotein metabolism and cardiometabolic disorders.MicroRNAs in heart failure: Non-coding regulators of metabolic function.Relevance of microRNA in metabolic diseases.miRNAs in atherosclerotic plaque initiation, progression, and rupture.miRNA and cholesterol homeostasis.miRNAs and High-Density Lipoprotein metabolism.miRNA regulation of LDL-cholesterol metabolism.microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis.Truths and controversies concerning the role of miRNAs in atherosclerosis and lipid metabolism.MicroRNAs and lipid metabolism.Nutriepigenomics and malnutrition.The transcription factor MafB promotes anti-inflammatory M2 polarization and cholesterol efflux in macrophages Novel Role of miR-33 in Regulating of Mitochondrial Function.

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Pharmacological inhibition of a microRNA family in nonhuman primates by a seed-targeting 8-mer antimiR

http://www.wikidata.org/entity/Q33661920

description

2013 nî lūn-bûn

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2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2013 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Pharmacological inhibition of ...... a seed-targeting 8-mer antimiR

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Pharmacological inhibition of ...... a seed-targeting 8-mer antimiR

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Pharmacological inhibition of ...... a seed-targeting 8-mer antimiR

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Pharmacological inhibition of ...... a seed-targeting 8-mer antimiR

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SCITRANSLMED.3006840

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Science Translational Medicine

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Pharmacological inhibition of ...... a seed-targeting 8-mer antimiR

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P2093

Anders M Näär

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Andreas Petri

http://www.w3.org/2001/XMLSchema#string

Andrew S deLemos

http://www.w3.org/2001/XMLSchema#string

Henrik F Hansen

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Johnathan R Whetstine

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Joshua C Black

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Matthew S Lawrence

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Raymond T Chung

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Robert E Gerszten

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Robert McGarrah

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P2860

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

MicroRNAs: target recognition and regulatory functions

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis

Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

The expansion of the metazoan microRNA repertoire

MicroRNAs in stress signaling and human disease

The functions of animal microRNAs

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

MicroRNAs: genomics, biogenesis, mechanism, and function

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212ra162

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10.1126/SCITRANSLMED.3006840

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212

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Marie W. Lindholm

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2013-11-01T00:00:00Z

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24259050

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