FGF2-activated ERK mitogen-activated protein kinase enhances Runx2 acetylation and stabilization. - Wikidata - wikimedia - TriplyDB

FGF2-activated ERK mitogen-activated protein kinase enhances Runx2 acetylation and stabilization.

FGF2-activated ERK mitogen-activated protein kinase enhances Runx2 acetylation and stabilization.

http://www.wikidata.org/entity/Q33661959

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Fibroblast growth factor signaling in skeletal development and disease Gap junctional regulation of signal transduction in bone cells Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy The toxicity of angiotensin converting enzyme inhibitors to larvae of the disease vectors Aedes aegypti and Anopheles gambiae Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis.Prolyl isomerase Pin1-mediated conformational change and subnuclear focal accumulation of Runx2 are crucial for fibroblast growth factor 2 (FGF2)-induced osteoblast differentiation.MPA-induced gene expression and stromal and parenchymal gene expression profiles in luminal murine mammary carcinomas with different hormonal requirements.Pin1-mediated Runx2 modification is critical for skeletal development Role of glucocorticoid-induced leucine zipper (GILZ) in bone acquisition Scanning probe-enabled nanocombinatorics define the relationship between fibronectin feature size and stem cell fate.Bent bone dysplasia syndrome reveals nucleolar activity for FGFR2 in ribosomal DNA transcription.The prolyl hydroxylase inhibitor dimethyloxalylglycine enhances dentin sialophoshoprotein expression through VEGF-induced Runx2 stabilization O-GlcNAc modification of the runt-related transcription factor 2 (Runx2) links osteogenesis and nutrient metabolism in bone marrow mesenchymal stem cells.Loss of Runx2 in committed osteoblasts impairs postnatal skeletogenesis.Lung tumor-associated osteoblast-derived bone morphogenetic protein-2 increased epithelial-to-mesenchymal transition of cancer by Runx2/Snail signaling pathway.Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agents ERK acts in parallel to PKCδ to mediate the connexin43-dependent potentiation of Runx2 activity by FGF2 in MC3T3 osteoblasts.Novel application of luciferase assay for the in vitro functional assessment of KAL1 variants in three females with septo-optic dysplasia (SOD).Reciprocal Control of Osteogenic and Adipogenic Differentiation by ERK/MAP Kinase Phosphorylation of Runx2 and PPARγ Transcription Factors.BMP-2 differentially modulates FGF-2 isoform effects in osteoblasts from newborn transgenic mice Inhibition of connexin 43 prevents trauma-induced heterotopic ossification.Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells.Deficiency of Sef is associated with increased postnatal cortical bone mass by regulating Runx2 activity.Molecular mechanisms of osteoblast/osteocyte regulation by connexin43.TGF-β inhibits osteogenesis by upregulating the expression of ubiquitin ligase SMURF1 via MAPK-ERK signaling.Pin1, the Master Orchestrator of Bone Cell Differentiation.PCAF acetylates Runx2 and promotes osteoblast differentiation.Tumor necrosis factor-α enhances the transcription of Smad ubiquitination regulatory factor 1 in an activating protein-1- and Runx2-dependent manner.Functional characterization of a novel FGFR2 mutation, E731K, in craniosynostosis.Spata4 promotes osteoblast differentiation through Erk-activated Runx2 pathway.BCL11B regulates sutural patency in the mouse craniofacial skeleton.TGF-β regulates phosphorylation and stabilization of Sox9 protein in chondrocytes through p38 and Smad dependent mechanisms.Direct Delivery of Recombinant Pin1 Protein Rescued Osteoblast Differentiation of Pin1-Deficient Cells.Pin1 plays a critical role as a molecular switch in canonical BMP signaling.Control of the Osteoblast Lineage by Mitogen-Activated Protein Kinase Signaling.Sprouty 2, an Early Response Gene Regulator of FosB and Mesenchymal Stem Cell Proliferation During Mechanical Loading and Osteogenic Differentiation.An HDAC Inhibitor, Entinostat/MS-275, Partially Prevents Delayed Cranial Suture Closure in Heterozygous Runx2 Null Mice.Connexin43 and Runx2 Interact to Affect Cortical Bone Geometry, Skeletal Development, and Osteoblast and Osteoclast Function.FGF Signaling Prevents the Terminal Differentiation of Odontoblasts.Characterization of Runx2 phosphorylation sites required for TGF-β1-mediated stimulation of matrix metalloproteinase-13 expression in osteoblastic cells.

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P2860

FGF2-activated ERK mitogen-activated protein kinase enhances Runx2 acetylation and stabilization.

http://www.wikidata.org/entity/Q33661959

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

FGF2-activated ERK mitogen-act ...... acetylation and stabilization.

@ast

FGF2-activated ERK mitogen-act ...... acetylation and stabilization.

@en

type

label

FGF2-activated ERK mitogen-act ...... acetylation and stabilization.

@ast

FGF2-activated ERK mitogen-act ...... acetylation and stabilization.

@en

prefLabel

FGF2-activated ERK mitogen-act ...... acetylation and stabilization.

@ast

FGF2-activated ERK mitogen-act ...... acetylation and stabilization.

@en

P1433

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JBC.M109.055053

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Journal of Biological Chemistry

P1476

FGF2-activated ERK mitogen-act ...... acetylation and stabilization.

@en

P2093

Hyun-Jung Kim

http://www.w3.org/2001/XMLSchema#string

Hyun-Mo Ryoo

http://www.w3.org/2001/XMLSchema#string

Jeong-Hwa Baek

http://www.w3.org/2001/XMLSchema#string

Kyung-Mi Woo

http://www.w3.org/2001/XMLSchema#string

Ok-Jin Park

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation

BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression

P304

3568-3574

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scholarly article

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10.1074/JBC.M109.055053

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6

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285

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20007706

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2823497

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