Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice. - Wikidata - wikimedia - TriplyDB

Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.

Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.

http://www.wikidata.org/entity/Q33664639

about

Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression No effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancer Profilin 1 as a target for cathepsin X activity in tumor cells Identification of a myeloid-derived suppressor cell cystatin-like protein that inhibits metastasis For robust big data analyses: a collection of 150 important pro-metastatic genes Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients.A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis Cathepsin B expression in colorectal cancer in a Middle East population: Potential value as a tumor biomarker for late disease stages.Characterization of the MDSC proteome associated with metastatic murine mammary tumors using label-free mass spectrometry and shotgun proteomics Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.Induction of premalignant host responses by cathepsin x/z-deficiency in Helicobacter pylori-infected mice.Alternative activation of tumor-associated macrophages by IL-4: priming for protumoral functions.Development of activity-based probes for cathepsin X.The role of Cathepsin S as a marker of prognosis and predictor of chemotherapy benefit in adjuvant CRC: a pilot study Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer.Cathepsin X Cleaves Profilin 1 C-Terminal Tyr139 and Influences Clathrin-Mediated Endocytosis.Differential Impact of Cysteine Cathepsins on Genetic Mouse Models of De novo Carcinogenesis: Cathepsin B as Emerging Therapeutic Target.Cathepsin X in serum from patients with colorectal cancer: relation to prognosis.Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer Melittin suppresses cathepsin S-induced invasion and angiogenesis via blocking of the VEGF-A/VEGFR-2/MEK1/ERK1/2 pathway in human hepatocellular carcinoma Cross-talk between Dopachrome Tautomerase and Caveolin-1 Is Melanoma Cell Phenotype-specific and Potentially Involved in Tumor Progression.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Inhibition of cathepsin X enzyme influences the immune response of THP-1 cells and dendritic cells infected with Helicobacter pylori.Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model.Improved quenched fluorescent probe for imaging of cysteine cathepsin activity.Cathepsin B as a potential prognostic and therapeutic marker for human lung squamous cell carcinoma.Proteolytic networks in cancer Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters.Synthesis, identification and in vivo studies of tumor-targeting agent peptide doxorubicin (PDOX) to treat peritoneal carcinomatosis of gastric cancer with similar efficacy but reduced toxicity.Specialized roles for cysteine cathepsins in health and disease.Cancer-associated lysosomal changes: friends or foes?Cysteine cathepsins and their potential in clinical therapy and biomarker discovery.Design of a highly selective quenched activity-based probe and its application in dual color imaging studies of cathepsin S activity localization.Proteomic Identification of Cysteine Cathepsin Substrates Shed from the Surface of Cancer Cells.Lysosomal processing of progranulin Inactivation of tristetraprolin in chronic hypoxia provokes the expression of cathepsin B.Nicotine alters the proteome of two human pancreatic duct cell lines.

P2860

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P2860

Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.

http://www.wikidata.org/entity/Q33664639

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2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Synergistic antitumor effects ...... ession and metastasis in mice.

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Synergistic antitumor effects ...... ession and metastasis in mice.

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type

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Synergistic antitumor effects ...... ession and metastasis in mice.

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Synergistic antitumor effects ...... ession and metastasis in mice.

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Synergistic antitumor effects ...... ession and metastasis in mice.

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Synergistic antitumor effects ...... ession and metastasis in mice.

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Proceedings of the National Academy of Sciences of the United States of America

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Synergistic antitumor effects ...... ression and metastasis in mice

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Anne Schwinde

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Christoph Peters

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Fee Werner

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Kathrin Sachse

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Lisa Sevenich

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Mieczyslaw Gajda

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Nicole Klemm

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Olga Vasiljeva

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P2860

Cathepsin Z, a novel human cysteine proteinase with a short propeptide domain and a unique chromosomal location

Human procathepsin B interacts with the annexin II tetramer on the surface of tumor cells

Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease

Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up

Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools.

Human cathepsin X: a novel cysteine protease of the papain family with a very short proregion and unique insertions.

Expression of cathepsins B and S in the progression of prostate carcinoma.

Matrix-degrading proteases and angiogenesis during development and tumor formation.

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2497-2502

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6

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107

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Jan M. Deussing

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Sebastian Müller

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2010-01-21T00:00:00Z

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41408633

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20133781

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2823914

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