Structure-based discovery of Tipranavir disodium (PNU-140690E): a potent, orally bioavailable, nonpeptidic HIV protease inhibitor.
about
In vitro antiviral activity of the novel, tyrosyl-based human immunodeficiency virus (HIV) type 1 protease inhibitor brecanavir (GW640385) in combination with other antiretrovirals and against a panel of protease inhibitor-resistant HIVUnique Thermodynamic Response of Tipranavir to Human Immunodeficiency Virus Type 1 Protease Drug Resistance MutationsInteraction of ritonavir-boosted tipranavir with loperamide does not result in loperamide-associated neurologic side effects in healthy volunteers.A sensitive assay using a native protein substrate for screening HIV-1 maturation inhibitors targeting the protease cleavage site between the matrix and capsidReview of tipranavir in the treatment of drug-resistant HIV.Resilience to resistance of HIV-1 protease inhibitors: profile of darunavir.New approaches to HIV protease inhibitor drug design II: testing the substrate envelope hypothesis to avoid drug resistance and discover robust inhibitorsTipranavir in the protease inhibitors arena.Steady-state disposition of the nonpeptidic protease inhibitor tipranavir when coadministered with ritonavir.
P2860
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P2860
Structure-based discovery of Tipranavir disodium (PNU-140690E): a potent, orally bioavailable, nonpeptidic HIV protease inhibitor.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Structure-based discovery of T ...... ptidic HIV protease inhibitor.
@ast
Structure-based discovery of T ...... ptidic HIV protease inhibitor.
@en
type
label
Structure-based discovery of T ...... ptidic HIV protease inhibitor.
@ast
Structure-based discovery of T ...... ptidic HIV protease inhibitor.
@en
prefLabel
Structure-based discovery of T ...... ptidic HIV protease inhibitor.
@ast
Structure-based discovery of T ...... ptidic HIV protease inhibitor.
@en
P1433
P1476
Structure-based discovery of T ...... ptidic HIV protease inhibitor.
@en
P2093
J W Strohbach
S Thaisrivongs
P356
10.1002/(SICI)1097-0282(1999)51:1<51::AID-BIP6>3.3.CO;2-L
P577
1999-01-01T00:00:00Z