B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene
about
Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fosA novel cysteine-rich sequence-specific DNA-binding protein interacts with the conserved X-box motif of the human major histocompatibility complex class II genes via a repeated Cys-His domain and functions as a transcriptional repressorFunctional roles of the transcription factor Oct-2A and the high mobility group protein I/Y in HLA-DRA gene expressionRFX1, a single DNA-binding protein with a split dimerization domain, generates alternative complexesIdentification of a transcription factor that binds to the S box of the I-A beta gene of the major histocompatibility complexEvidence for a trans-acting factor that regulates the transcription of class II major histocompatibility complex genes: genetic and functional analysis.X-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements.Interferon gamma response region in the promoter of the human DPA gene.The octamer motif is a B-lymphocyte-specific regulatory element of the HLA-DR alpha gene promoter.The MHC class II E beta promoter: a complex arrangement of positive and negative elements determines B cell and interferon-gamma (IFN-gamma) regulated expression.Two B cell factors bind the HLA-DRA X box region and recognize different subsets of HLA class II promoters.Hyperexpression of interferon-gamma-induced MHC class II genes associated with reorganization of the cytoskeletonShared promoter elements between a viral superantigen and the major histocompatibility complex class II-associated invariant chain.Regulatory factor-X binding to mutant HLA-DRA promoter sequencesMapping cis-acting defects in promoters of transcriptionally silent DQA2, DQB2, and DOB genes.cis-acting sequences required for class II gene regulation by interferon gamma and tumor necrosis factor alpha in a murine macrophage cell line.A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoterTwo cis-DNA elements involved in myeloid-cell-specific expression and gamma interferon (IFN-gamma) activation of the human high-affinity Fc gamma receptor gene: a novel IFN regulatory mechanism.Sequence elements required for activity of a murine major histocompatibility complex class II promoter bind common and cell-type-specific nuclear factors.Transcriptional control of the invariant chain gene involves promoter and enhancer elements common to and distinct from major histocompatibility complex class II genes.Two DNA-binding proteins discriminate between the promoters of different members of the major histocompatibility complex class II multigene family.Identification of cis sequences controlling efficient position-independent tissue-specific expression of human major histocompatibility complex class I genes in transgenic mice.Characterization of promoter elements of an interferon-inducible Ly-6E/A differentiation antigen, which is expressed on activated T cells and hematopoietic stem cells.DNA binding of the mouse class II major histocompatibility CCAAT factor depends on two components.Delineation of a previously unrecognized cis-acting element required for HLA class II gene expression.Characterization of the promoter of the human gene encoding the high-affinity IgG receptor: transcriptional induction by gamma-interferon is mediated through common DNA response elements.Interferon gamma regulates binding of two nuclear protein complexes in a macrophage cell line.The major histocompatibility complex class II promoter-binding protein RFX (NF-X) is a methylated DNA-binding protein.Allele-specific DNA-protein interactions associated with the X-box regulatory region of the DQB1*0302 gene.An ATF/CREB binding motif is required for aberrant constitutive expression of the MHC class II DR alpha promoter and activation by SV40 T-antigen.The MHC class II transactivator (CIITA) requires conserved leucine charged domains for interactions with the conserved W box promoter element.Human HLA-DR alpha gene: a rare oligonucleotide (GTATA) identifies an upstream sequence required for nuclear protein binding.DNA-protein interactions at the interferon-responsive promoter: evidences for an involvement of phosphorylation.Mutational analysis of the DRA promoter: cis-acting sequences and trans-acting factors.Evidence for multiple major histocompatibility class II X-box binding proteins.Identification of the transcription factors NF-YA and NF-YB as factors A and B that bound to the promoter of the major histocompatibility complex class II gene I-A beta.The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities.Major histocompatibility complex class II transcriptional platform: assembly of nuclear factor Y and regulatory factor X (RFX) on DNA requires RFX5 dimers.Complex architecture of major histocompatibility complex class II promoters: reiterated motifs and conserved protein-protein interactionsB-cell factor 1 is required for optimal expression of the DRA promoter in B cells.
P2860
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P2860
B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene
description
1988 nî lūn-bûn
@nan
1988 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene
@ast
B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene
@en
type
label
B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene
@ast
B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene
@en
prefLabel
B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene
@ast
B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene
@en
P2093
P2860
P356
P1476
B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene
@en
P2093
Nakanishi M
Peterlin BM
P2860
P304
P356
10.1073/PNAS.85.22.8598
P407
P577
1988-11-01T00:00:00Z