Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis.
about
Microsomal prostaglandin E synthase-1 promotes hepatocarcinogenesis through activation of a novel EGR1/β-catenin signaling axisp62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogrammingIdentification of a novel class of anti-inflammatory compounds with anti-tumor activity in colorectal and lung cancers.Identification and development of mPGES-1 inhibitors: where we are at?Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity.Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways.Prostaglandins in cancer cell adhesion, migration, and invasionmPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity.Genetic deletion of microsomal prostaglandin E synthase-1 suppresses mouse mammary tumor growth and angiogenesis.Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and -186 expression: Novel mechanism of VEGF modulation in prostate cancermPGES-1 as a target for cancer suppression: A comprehensive invited review "Phospholipase A2 and lipid mediators".Characterization of microsomal prostaglandin E synthase 1 inhibitors.Pharmacophore modelling, atom-based 3D-QSAR generation and virtual screening of molecules projected for mPGES-1 inhibitory activity.Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review.EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity.A Novel Multi-step Virtual Screening for the Identification of Human and Mouse mPGES-1 Inhibitors.Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1.Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma MetastasisMicrosomal prostaglandin E synthase-1 is induced in alzheimer's disease and its deletion mitigates alzheimer's disease-like pathology in a mouse model.Prostaglandin terminal synthases as novel therapeutic targets.Inhibition of Microsomal Prostaglandin E Synthase-1 in Cancer-Associated Fibroblasts Suppresses Neuroblastoma Tumor Growth.
P2860
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P2860
Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Microsomal prostaglandin E syn ...... owth, invasion and metastasis.
@ast
Microsomal prostaglandin E syn ...... owth, invasion and metastasis.
@en
type
label
Microsomal prostaglandin E syn ...... owth, invasion and metastasis.
@ast
Microsomal prostaglandin E syn ...... owth, invasion and metastasis.
@en
prefLabel
Microsomal prostaglandin E syn ...... owth, invasion and metastasis.
@ast
Microsomal prostaglandin E syn ...... owth, invasion and metastasis.
@en
P2093
P2860
P356
P1433
P1476
Microsomal prostaglandin E syn ...... owth, invasion and metastasis.
@en
P2093
Daisuke Kamei
Ichiro Kudo
Makoto Murakami
Masataka Majima
Satoshi Uematsu
Shuntaro Hara
Toshiharu Ishii
Yoshihito Nakatani
Yuka Sasaki
Yukio Ishikawa
P2860
P304
P356
10.1042/BJ20090045
P407
P50
P577
2009-12-23T00:00:00Z