Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis. - Wikidata - wikimedia - TriplyDB

Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis.

Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis.

http://www.wikidata.org/entity/Q33675073

about

Microsomal prostaglandin E synthase-1 promotes hepatocarcinogenesis through activation of a novel EGR1/β-catenin signaling axis p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming Identification of a novel class of anti-inflammatory compounds with anti-tumor activity in colorectal and lung cancers.Identification and development of mPGES-1 inhibitors: where we are at?Selective PGE(2) suppression inhibits colon carcinogenesis and modifies local mucosal immunity.Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways.Prostaglandins in cancer cell adhesion, migration, and invasion mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity.Genetic deletion of microsomal prostaglandin E synthase-1 suppresses mouse mammary tumor growth and angiogenesis.Linking microsomal prostaglandin E Synthase-1/PGE-2 pathway with miR-15a and -186 expression: Novel mechanism of VEGF modulation in prostate cancer mPGES-1 as a target for cancer suppression: A comprehensive invited review "Phospholipase A2 and lipid mediators".Characterization of microsomal prostaglandin E synthase 1 inhibitors.Pharmacophore modelling, atom-based 3D-QSAR generation and virtual screening of molecules projected for mPGES-1 inhibitory activity.Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review.EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity.A Novel Multi-step Virtual Screening for the Identification of Human and Mouse mPGES-1 Inhibitors.Genetic-deletion of Cyclooxygenase-2 Downstream Prostacyclin Synthase Suppresses Inflammatory Reactions but Facilitates Carcinogenesis, unlike Deletion of Microsomal Prostaglandin E Synthase-1.Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis Microsomal prostaglandin E synthase-1 is induced in alzheimer's disease and its deletion mitigates alzheimer's disease-like pathology in a mouse model.Prostaglandin terminal synthases as novel therapeutic targets.Inhibition of Microsomal Prostaglandin E Synthase-1 in Cancer-Associated Fibroblasts Suppresses Neuroblastoma Tumor Growth.

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P2860

Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis.

http://www.wikidata.org/entity/Q33675073

description

2009 nî lūn-bûn

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2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Microsomal prostaglandin E syn ...... owth, invasion and metastasis.

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Microsomal prostaglandin E syn ...... owth, invasion and metastasis.

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Microsomal prostaglandin E syn ...... owth, invasion and metastasis.

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Microsomal prostaglandin E syn ...... owth, invasion and metastasis.

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Microsomal prostaglandin E syn ...... owth, invasion and metastasis.

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Microsomal prostaglandin E syn ...... owth, invasion and metastasis.

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Microsomal prostaglandin E syn ...... owth, invasion and metastasis.

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P2093

Daisuke Kamei

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Ichiro Kudo

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Makoto Murakami

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Masataka Majima

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Satoshi Uematsu

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Shuntaro Hara

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Toshiharu Ishii

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Yoshihito Nakatani

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Yuka Sasaki

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Yukio Ishikawa

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P2860

Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group

Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial

Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis

Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice

Cloning, expression, and up-regulation of inducible rat prostaglandin e synthase during lipopolysaccharide-induced pyresis and adjuvant-induced arthritis

Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice

Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2

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361-371

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