EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells. - Wikidata - wikimedia - TriplyDB

EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.

EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.

http://www.wikidata.org/entity/Q33679446

about

Survivin and Tumorigenesis: Molecular Mechanisms and Therapeutic Strategies Survivin - biology and potential as a therapeutic target in oncology Growth-Blocking Peptides As Nutrition-Sensitive Signals for Insulin Secretion and Body Size Regulation Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription Targeting survivin in cancer: novel drug development approaches.Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.Ca2+ influx through L-type Ca2+ channels and Ca2+-induced Ca2+ release regulate cAMP accumulation and Epac1-dependent ERK 1/2 activation in INS-1 cells.Indoleamine 2,3-dioxygenase-1 (IDO1) enhances survival and invasiveness of endometrial stromal cells via the activation of JNK signaling pathway.MAPK1 is required for establishing the pattern of cell proliferation and for cell survival during lens development.Survivin as a preferential target for cancer therapy.Polypeptides from the Skin of Rana chensinensis Exert the Antioxidant and Antiapoptotic Activities on HaCaT Cells.Prolactin-stimulated survivin induction is required for beta cell mass expansion during pregnancy in mice.Depletion of PAK1 enhances ubiquitin-mediated survivin degradation in pancreatic β-cells.HER2 stabilizes survivin while concomitantly down-regulating survivin gene transcription by suppressing Notch cleavage.Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors.Targeting PRPK Function Blocks Colon Cancer Metastasis.Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation.In vivo activation of the PI3K-Akt pathway in mouse beta cells by the EGFR mutation L858R protects against diabetes.Formula Inhibits Pancreatic Cell Apoptosis in Type 2 Diabetes Mellitus via MEK-ERK-Caspase-3 Signaling Pathway Cellular signaling pathways regulating β-cell proliferation as a promising therapeutic target in the treatment of diabetes

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P2860

EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.

http://www.wikidata.org/entity/Q33679446

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

EGF regulates survivin stabili ...... -secreting pancreatic β-cells.

@ast

EGF regulates survivin stabili ...... -secreting pancreatic β-cells.

@en

type

label

EGF regulates survivin stabili ...... -secreting pancreatic β-cells.

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EGF regulates survivin stabili ...... -secreting pancreatic β-cells.

@en

prefLabel

EGF regulates survivin stabili ...... -secreting pancreatic β-cells.

@ast

EGF regulates survivin stabili ...... -secreting pancreatic β-cells.

@en

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1471-2199-11-66

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BMC Molecular Biology

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EGF regulates survivin stabili ...... n-secreting pancreatic β-cells

@en

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Andrea Kassai

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Charlotte M Boney

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Denisse Izquierdo

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Haijuan Wang

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Katarina Gambosova

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Kelly Cleveland

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Michael P Holloway

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Rachel A Altura

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P2860

Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin

Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype

Chromosome alignment and segregation regulated by ubiquitination of survivin

Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo

Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

Untangling the ErbB signalling network

Functional roles of ubiquitin-like domain (ULD) and ubiquitin-binding domain (UBD) containing proteins

Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting

IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs

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1471-2199-11-66

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66

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scholarly article

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10.1186/1471-2199-11-66

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Zachary A. Cooper

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46107189

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