Effect of mutations and variations of HLA-A2 on recognition of a virus peptide epitope by cytotoxic T lymphocytes.
about
Structure of a complex of the human alpha/beta T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRB1*0401): insight into TCR cross-restriction and alloreactivMultiple HLA A11-restricted cytotoxic T-lymphocyte epitopes of different immunogenicities in the Epstein-Barr virus-encoded nuclear antigen 4.HLA-B37 and HLA-A2.1 molecules bind largely nonoverlapping sets of peptidesPoint mutations define positions in HLA-DR3 molecules that affect antigen presentation.Alloreactivity studied with mutants of HLA-A2.Roles of the six peptide-binding pockets of the HLA-A2 molecule in allorecognition by human cytotoxic T-cell clones.Toward computational determination of peptide-receptor structure.Evidence of widespread binding of HLA class I molecules to peptides.Lysis of human melanoma cells by autologous cytolytic T cell clones. Identification of human histocompatibility leukocyte antigen A2 as a restriction element for three different antigens.Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein.H-2Dd exploits a four residue peptide binding motif.Genome-wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A, and Identification of ZBTB10 and Three Distinct HLA Associations.Dissection of H-2Db-restricted cytotoxic T-lymphocyte epitopes on simian virus 40 T antigen by the use of synthetic peptides and H-2Dbm mutants.Conformational constraints involved in MHC class I restricted antigen presentation.Genome-wide screening of human T-cell epitopes in influenza A virus reveals a broad spectrum of CD4(+) T-cell responses to internal proteins, hemagglutinins, and neuraminidases.Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptideThe structure of the antigen-binding groove of major histocompatibility complex class I molecules determines specific selection of self-peptidesPositioning of a peptide in the cleft of HLA-A2 by complementing amino acid changes.A PCR-SSP method to specifically select HLA-A*0201 individuals for immunotherapeutic studies.Identification of tumor antigen-specific cytotoxic T lymphocytes cross-recognizing allogeneic major histocompatibility class I molecules.Introduction of a point mutation into an HLA class I single-chain trimer induces enhancement of CTL priming and antitumor immunity.HLA-A2 polymorphism and immune functions.HLA-A2 subtypes are functionally distinct in peptide binding and presentation.Translocation of peptides through microsomal membranes is a rapid process and promotes assembly of HLA-B27 heavy chain and beta 2-microglobulin translated in vitro.Intensity of class I antigen expression on human tumour cell lines and its relevance to the efficiency of non-MHC-restricted killingA class I cDNA from SPAFAS line-11 chickens.Determination of HLA‐A*02 alleles using nested PCR‐SSP in Korean population
P2860
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P2860
Effect of mutations and variations of HLA-A2 on recognition of a virus peptide epitope by cytotoxic T lymphocytes.
description
1988 nî lūn-bûn
@nan
1988 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
name
Effect of mutations and variat ...... pe by cytotoxic T lymphocytes.
@ast
Effect of mutations and variat ...... pe by cytotoxic T lymphocytes.
@en
type
label
Effect of mutations and variat ...... pe by cytotoxic T lymphocytes.
@ast
Effect of mutations and variat ...... pe by cytotoxic T lymphocytes.
@en
prefLabel
Effect of mutations and variat ...... pe by cytotoxic T lymphocytes.
@ast
Effect of mutations and variat ...... pe by cytotoxic T lymphocytes.
@en
P2093
P2860
P356
P1476
Effect of mutations and variat ...... pe by cytotoxic T lymphocytes.
@en
P2093
A J McMichael
J Santos-Aguado
P2860
P304
P356
10.1073/PNAS.85.23.9194
P407
P577
1988-12-01T00:00:00Z