The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors.
about
HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxisHIV-1 Nef impairs MHC class II antigen presentation and surface expressionMechanism for down-regulation of CD28 by Nef.Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functionsCounteraction of tetherin antiviral activity by two closely related SIVs differing by the presence of a Vpu geneA hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2.The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck.Hck SH3 domain-dependent abrogation of Nef-induced class 1 MHC down-regulation.Design and use of an inducibly activated human immunodeficiency virus type 1 Nef to study immune modulation.Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity.Mechanisms of HIV-1 to escape from the host immune surveillance.Porcine reproductive and respiratory syndrome (PRRS): an immune dysregulatory pandemic.Role of accessory proteins of HTLV-1 in viral replication, T cell activation, and cellular gene expression.Expression of CD154 by a simian immunodeficiency virus vector induces only transitory changes in rhesus macaques.High viremia is associated with high levels of in vivo major histocompatibility complex class I Downregulation in rhesus macaques infected with simian immunodeficiency virus SIVmac239.In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail.Hepatitis C virus NS2 protein is phosphorylated by the protein kinase CK2 and targeted for degradation to the proteasome.Partial activation and induction of apoptosis in CD4(+) and CD8(+) T lymphocytes by conformationally authentic noninfectious human immunodeficiency virus type 1.Genetic and functional diversity of human immunodeficiency virus type 1 subtype B Nef primary isolatesHuman cytomegalovirus protein US2 interferes with the expression of human HFE, a nonclassical class I major histocompatibility complex molecule that regulates iron homeostasis.Nef-induced CD4 downregulation: a diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to beta-COP.HIV dynamics with multiple infections of target cells.Impaired regulation of HLA-DR expression in human immunodeficiency virus-infected monocytes.Critical role of human T-lymphotropic virus type 1 accessory proteins in viral replication and pathogenesisControl of MHC class I traffic from the endoplasmic reticulum by cellular chaperones and viral anti-chaperones.Endocytosis in viral replication.Novel Nipah virus immune-antagonism strategy revealed by experimental and computational study.HIV-1 Nef enhances dendritic cell-mediated viral transmission to CD4+ T cells and promotes T-cell activation.Simian immunodeficiency virus Nef protein delays the progression of CD4+ T cells through G1/S phase of the cell cycle.Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMC.Lentivirus and foamy virus vectors: novel gene therapy tools.Cellular gene expression upon human immunodeficiency virus type 1 infection of CD4(+)-T-cell linesnef gene is required for robust productive infection by simian immunodeficiency virus of T-cell-rich paracortex in lymph nodes.Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes.S100A9 protein is a novel ligand for the CD85j receptor and its interaction is implicated in the control of HIV-1 replication by NK cells.Cooperative interactions of simian immunodeficiency virus Nef, AP-2, and CD3-zeta mediate the selective induction of T-cell receptor-CD3 endocytosis.Orf-I and orf-II-encoded proteins in HTLV-1 infection and persistence.Evidence of a role for soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) machinery in HIV-1 assembly and release.Proteomic profiling of SupT1 cells reveal modulation of host proteins by HIV-1 Nef variants
P2860
Q21146434-459915B2-9A91-44F2-BE24-CEDBCFE2BA38Q22248080-6DB76358-9905-4601-B9EE-5F2912940520Q24291079-5AAB4CBA-2CBC-474F-8832-C4B12B90B93AQ24297949-4F350699-7711-4A74-961C-B2E2B05F38A0Q24524045-6E243D66-6661-49BA-815F-5414D1D55A1EQ28730542-B16DDF30-19C1-48A0-B6BD-8FB7DAC4442DQ28768294-570F89AB-7CCD-478A-A384-520DA2D3CEB3Q30167954-542B144C-D58D-468B-9FDF-E6BFC39134E8Q30168004-16825669-B679-4D15-B590-7D58E1C4D543Q30306643-F79857BA-F22F-49D7-A0D8-98F69FC05AFEQ30312050-A5F12CCC-045A-41EC-8ACD-8BB0D0C33C50Q30327140-5CB07C19-114E-42E3-909F-B55C12FA04E0Q30364184-9F5FE6CD-01A0-4842-ABDD-FB58EF1CBDB3Q33206633-F883B184-4557-45DC-BE26-E5AF40457EE4Q33724139-2C8B0242-2EE6-4944-ACB2-F06E1CFCF2B8Q33826963-ABD53C93-FB88-459D-A564-BB59718A6B74Q33834814-10F9104B-24C9-49F1-9B75-35124D41C702Q33835218-2ABD7D22-0461-4651-B213-8A5D5BCBA655Q33836036-9530466A-A246-48BD-A6F3-B16E1EE2F143Q33837307-EDD40FDE-3EBE-4B62-B59E-38C2A391213CQ33848523-3035E6F7-529C-4F85-A8FF-524DFDBC507CQ33851483-2CF437F5-60E2-4A79-B1B7-C6BADC5D9D00Q33852032-09CCBCF1-9869-43AB-8189-22327DD6FD67Q33944148-B685FA3B-07FE-47E4-84A1-A94838F20F80Q33969941-87A8D6E5-C79D-4886-AAE8-9F3F44465221Q34156628-27E7708F-E5E7-4DDB-85CD-2F760C92C86AQ34156695-B5BFA324-F5B2-4A86-8533-1E551FEC562DQ34190582-2B39DE77-B08F-466A-809D-9CE8E2C8F89AQ34222643-9B25E65D-A205-4E8F-9A19-2F35E14E1E05Q34335576-2A885971-0916-40B0-B860-2C9205D290A9Q34357068-85F23546-9FBB-440B-B3D1-02EA9D38D225Q34452109-BA827037-3A5A-46FA-8AB2-772C66FC9156Q34465453-95ED980F-5326-4282-B524-EF79B9E61787Q34782209-144A39B8-77F4-4E2E-BDC6-CB5B0A1F0360Q34999681-BA980248-A4A8-4CBC-93A3-0EA1F76E0890Q35025680-66368340-E597-4FD6-B557-F13E22A8BDE3Q35105271-358C8B38-CB83-458E-A8CE-011AFF657224Q35261449-672FCA12-BF0D-438F-98B5-E8AD3B90918CQ35313971-1F22386E-39AE-437A-972D-EA6438CC7A68Q35601697-5E2A2BB6-617D-491E-BF25-FCA50FF846BF
P2860
The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors.
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The downregulation of CD4 and ...... ion of cell surface receptors.
@ast
The downregulation of CD4 and ...... ion of cell surface receptors.
@en
type
label
The downregulation of CD4 and ...... ion of cell surface receptors.
@ast
The downregulation of CD4 and ...... ion of cell surface receptors.
@en
prefLabel
The downregulation of CD4 and ...... ion of cell surface receptors.
@ast
The downregulation of CD4 and ...... ion of cell surface receptors.
@en
P2093
P2860
P1476
The downregulation of CD4 and ...... ion of cell surface receptors.
@en
P2093
P2860
P356
10.1111/J.1600-065X.1999.TB01282.X
P577
1999-04-01T00:00:00Z