Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas
about
The role of endocytic Rab GTPases in regulation of growth factor signaling and the migration and invasion of tumor cellsRab25 in cancer: a brief updateRab GTPases, membrane trafficking and diseasesRab-mediated vesicle trafficking in cancerGene expression correlations in human cancer cell lines define molecular interaction networks for epithelial phenotypeGrainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4, and Rab25A central role for vesicle trafficking in epithelial neoplasia: intracellular highways to carcinogenesis.Altered Mucins (MUC) trafficking in benign and malignant conditions.Integrin-mediated function of Rab GTPases in cancer progression.Bioinformatics analysis of Rab GDP dissociation inhibitor beta and its expression in non-small cell lung cancer.Identifying resistance mechanisms against five tyrosine kinase inhibitors targeting the ERBB/RAS pathway in 45 cancer cell lines.Rab GTPases as regulators of endocytosis, targets of disease and therapeutic opportunities.BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma.The Rab2A GTPase promotes breast cancer stem cells and tumorigenesis via Erk signaling activationRab25 increases cellular ATP and glycogen stores protecting cancer cells from bioenergetic stress.An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes.Rab GTPases implicated in inherited and acquired disorders.Predominant Rab-GTPase amplicons contributing to oral squamous cell carcinoma progression to metastasisRab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression.Novel functions for Rab GTPases in multiple aspects of tumour progression.Rab25 regulates integrin expression in polarized colonic epithelial cells.Rab25 regulates invasion and metastasis in head and neck cancer.Pathology of rodent models of intestinal cancer: progress report and recommendationsRab11-FIP1C Is a Critical Negative Regulator in ErbB2-Mediated Mammary Tumor ProgressionHigh RAB25 expression is associated with good clinical outcome in patients with locally advanced head and neck squamous cell carcinoma.Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation.Rab25 as a tumour suppressor in colon carcinogenesis.Rab11 proteins in health and disease.Animal models of human genetic diseases: do they need to be faithful to be useful?Late endosomal and lysosomal trafficking during integrin-mediated cell migration and invasion: cell matrix receptors are trafficked through the late endosomal pathway in a way that dictates how cells migrate.Integrin traffic - the update.Rab family of GTPases.Rab11 in disease progression.Protein trafficking in colorectal carcinogenesis-targeting and bypassing resistance to currently applied treatments.A proteomic approach to identify endosomal cargoes controlling cancer invasiveness.Disruption of Rab8a and Rab11a causes formation of basolateral microvilli in neonatal enteropathy.Extracellular Vesicles in Brain Tumor Progression.Overexpression of Rab25 promotes hepatocellular carcinoma cell proliferation and invasion.Integrin trafficking and tumor progression.Small GTPase Rab37 targets tissue inhibitor of metalloproteinase 1 for exocytosis and thus suppresses tumour metastasis.
P2860
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P2860
Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Loss of Rab25 promotes the dev ...... man colorectal adenocarcinomas
@ast
Loss of Rab25 promotes the dev ...... man colorectal adenocarcinomas
@en
type
label
Loss of Rab25 promotes the dev ...... man colorectal adenocarcinomas
@ast
Loss of Rab25 promotes the dev ...... man colorectal adenocarcinomas
@en
prefLabel
Loss of Rab25 promotes the dev ...... man colorectal adenocarcinomas
@ast
Loss of Rab25 promotes the dev ...... man colorectal adenocarcinomas
@en
P2093
P2860
P356
P1476
Loss of Rab25 promotes the dev ...... man colorectal adenocarcinomas
@en
P2093
Benjamin C Calhoun
Brian Condie
Hyuk-Joon Lee
J Joshua Smith
James R Goldenring
Ki Taek Nam
Lynne A Lapierre
Nancy R Manley
R Daniel Beauchamp
Robert J Coffey
P2860
P304
P356
10.1172/JCI40728
P407
P577
2010-02-08T00:00:00Z