T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1. - Wikidata - wikimedia - TriplyDB

T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.

T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.

http://www.wikidata.org/entity/Q33687647

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The establishment of B versus T cell identity Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network.Disruption of the C/EBPα-miR-182 balance impairs granulocytic differentiation.BMP signaling balances murine myeloid potential through SMAD-independent p38MAPK and NOTCH pathways.SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells 1,25-Dihydroxyvitamin D3 induces monocytic differentiation of human myeloid leukemia cells by regulating C/EBPβ expression through MEF2C Repression of Ccr9 transcription in mouse T lymphocyte progenitors by the Notch signaling pathway.Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia.Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL.TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow.Rbpj-κ mediated Notch signaling plays a critical role in development of hypothalamic Kisspeptin neurons.Hes1 triggers epithelial-mesenchymal transition (EMT)-like cellular marker alterations and promotes invasion and metastasis of nasopharyngeal carcinoma by activating the PTEN/AKT pathway.Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model.Notch signaling: switching an oncogene to a tumor suppressor.(-)-Epigallocatechin Gallate Targets Notch to Attenuate the Inflammatory Response in the Immediate Early Stage in Human Macrophages.Developmental gene networks: a triathlon on the course to T cell identity.Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control.The Groucho/Transducin-like enhancer of split protein family in animal development.Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells.Transcriptional regulation of early T-cell development in the thymus.Hematopoiesis and T-cell specification as a model developmental system.The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia.Cytokines, Transcription Factors, and the Initiation of T-Cell Development.GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate Chemokine polyreactivity of IL7Rα+CSF-1R+ lympho-myeloid progenitors in the developing fetal liver A HESitant decision for T cells.Genome-wide identification and analysis of basic helix-loop-helix domains in dog, Canis lupus familiaris.The clinicopathological significance of HES1 promoter hypomethylation in patients with colorectal cancer.IL-4/IL-13 Signaling Inhibits the Potential of Early Thymic Progenitors To Commit to the T Cell Lineage.MicroRNA-337-3p controls hepatobiliary gene expression and transcriptional dynamics during hepatic cell differentiation.CpG site DNA methylation of the CCAAT/enhancer-binding protein, alpha promoter in chicken lines divergently selected for fatness.Mixed phenotype acute leukemia contains heterogeneous genetic mutations by next-generation sequencing.

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T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.

http://www.wikidata.org/entity/Q33687647

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2013 nî lūn-bûn

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2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2013 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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T cell development requires co ...... ranscriptional repressor Hes1.

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Nature Immunology

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T cell development requires co ...... transcriptional repressor Hes1

@en

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Avinash Bhandoola

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Daniel A Zlotoff

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Dil Afroz Sultana

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J Jeremiah Bell

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Jonathan H DeLong

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Maria Elena De Obaldia

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Warren S Pear

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Xinxin Wang

http://www.w3.org/2001/XMLSchema#string

Yumi Yashiro-Ohtani

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P2860

Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations

Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

Signalling downstream of activated mammalian Notch

The Hes gene family: repressors and oscillators that orchestrate embryogenesis

Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects

Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1

Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3

Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split

Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha

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12

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Christelle Harly

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258252959

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