Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection
about
RNA-Seq profiling of spinal cord motor neurons from a presymptomatic SOD1 ALS mouseNeuronal matrix metalloproteinase-9 is a determinant of selective neurodegenerationGene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration.Motor neuron vulnerability and resistance in amyotrophic lateral sclerosis.Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity.A continuum of myofibers in adult rabbit extraocular muscle: force, shortening velocity, and patterns of myosin heavy chain colocalization.Transcriptional profiling of differentially vulnerable motor neurons at pre-symptomatic stage in the Smn (2b/-) mouse model of spinal muscular atrophy.Laser capture microscopy coupled with Smart-seq2 for precise spatial transcriptomic profiling.Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases.Extraocular motoneurons of the adult rat show higher levels of vascular endothelial growth factor and its receptor Flk-1 than other cranial motoneurons.Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS.Cross-disease comparison of amyotrophic lateral sclerosis and spinal muscular atrophy reveals conservation of selective vulnerability but differential neuromuscular junction pathology.Investigating cell death mechanisms in amyotrophic lateral sclerosis using transcriptomics.Can transcriptomics cut the gordian knot of amyotrophic lateral sclerosis?Directed midbrain and spinal cord neurogenesis from pluripotent stem cells to model development and disease in a dish.Ocular Motor Nerve Development in the Presence and Absence of Extraocular Muscle.ALS mouse model SOD1G93A displays early pathology of sensory small fibers associated to accumulation of a neurotoxic splice variant of peripherin.Mitochondrial oxidative phosphorylation transcriptome alterations in human amyotrophic lateral sclerosis spinal cord and blood.A Novel Short Isoform of Cytosolic PSD-95 Interactor (Cypin) Regulates Neuronal Development.Selective vulnerability in neuronal populations in nmd/SMARD1 mice.Escape from homeostasis: spinal microcircuits and progression of amyotrophic lateral sclerosis.
P2860
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P2860
Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Global gene expression profili ...... of degeneration and protection
@ast
Global gene expression profili ...... of degeneration and protection
@en
type
label
Global gene expression profili ...... of degeneration and protection
@ast
Global gene expression profili ...... of degeneration and protection
@en
prefLabel
Global gene expression profili ...... of degeneration and protection
@ast
Global gene expression profili ...... of degeneration and protection
@en
P2093
P2860
P356
P1433
P1476
Global gene expression profili ...... of degeneration and protection
@en
P2093
Martin Karlsson
Teresia Osborn
Wesley Ludwig
P2860
P304
P356
10.1093/BRAIN/AWQ167
P407
P577
2010-08-01T00:00:00Z