Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop
about
A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulationA novel role of Sprouty 2 in regulating cellular apoptosisFunctional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancersA functional interaction between sprouty proteins and caveolin-1Regulation of sprouty stability by Mnk1-dependent phosphorylation.Cbl controls EGFR fate by regulating early endosome fusion.The VASP-Spred-Sprouty domain puzzle.HECT domain-containing E3 ubiquitin ligase Nedd4 interacts with and ubiquitinates Sprouty2.The developing story of Sprouty and cancer.Sprouty 2 is an independent prognostic factor in breast cancer and may be useful in stratifying patients for trastuzumab therapyFunctional interaction between Env oncogene from Jaagsiekte sheep retrovirus and tumor suppressor Sprouty2.The MAPK pathway as an apoptosis enhancer in melanoma.Sprouty proteins inhibit receptor-mediated activation of phosphatidylinositol-specific phospholipase C.G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation.Sprouty4 is an endogenous negative modulator of TrkA signaling and neuronal differentiation induced by NGFSprouty2 downregulates angiogenesis during mouse skin wound healing.Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.Negative Regulation of Receptor Tyrosine Kinase (RTK) Signaling: A Developing FieldSprouty is a cytoplasmic target of adenoviral E1A oncoproteins to regulate the receptor tyrosine kinase signalling pathwayIdentification of a new Sprouty protein responsible for the inhibition of the Bombyx mori nucleopolyhedrovirus reproductionSprouty2 mediated tuning of signalling is essential for somite myogenesis.Regulation of cellular levels of Sprouty2 protein by prolyl hydroxylase domain and von Hippel-Lindau proteinsAn essential role for FGF receptor signaling in lens developmentSpry1 as a novel regulator of erythropoiesis, EPO/EPOR target, and suppressor of JAK2.Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 proteinCurrent challenges in quantitative modeling of epidermal growth factor signaling.ERK MAP kinase in G cell cycle progression and cancer.Sprouty2 and -4 hypomorphism promotes neuronal survival and astrocytosis in a mouse model of kainic acid induced neuronal damageCell density-dependent inhibition of epidermal growth factor receptor signaling by p38alpha mitogen-activated protein kinase via Sprouty2 downregulationKit K641E oncogene up-regulates Sprouty homolog 4 and trophoblast glycoprotein in interstitial cells of Cajal in a murine model of gastrointestinal stromal tumoursIntermolecular interactions of Sprouty proteins and their implications in development and disease.Receptor tyrosine kinase ubiquitylation involves the dynamic regulation of Cbl-Spry2 by intersectin 1 and the Shp2 tyrosine phosphatase.Receptor tyrosine kinase (RTK) signalling in the control of neural stem and progenitor cell (NSPC) development.Tumor adaptation and resistance to RAF inhibitors.Sprouty 2 binds ESCRT-II factor Eap20 and facilitates HIV-1 gag release.Cbl-family ubiquitin ligases and their recruitment of CIN85 are largely dispensable for epidermal growth factor receptor endocytosis.The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.Differential parsing of EGFR endocytic flux among parallel internalization pathways in lung cancer cells with EGFR-activating mutations.Human sprouty1 suppresses urokinase receptor-stimulated cell migration and invasion.Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancer.
P2860
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P2860
Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
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2004 թվականի մարտին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
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2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
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2004年论文
@wuu
name
Tyrosine phosphorylation of Sp ...... ignaling: a dual feedback loop
@ast
Tyrosine phosphorylation of Sp ...... ignaling: a dual feedback loop
@en
type
label
Tyrosine phosphorylation of Sp ...... ignaling: a dual feedback loop
@ast
Tyrosine phosphorylation of Sp ...... ignaling: a dual feedback loop
@en
prefLabel
Tyrosine phosphorylation of Sp ...... ignaling: a dual feedback loop
@ast
Tyrosine phosphorylation of Sp ...... ignaling: a dual feedback loop
@en
P2093
P2860
P356
P1476
Tyrosine phosphorylation of Sp ...... ignaling: a dual feedback loop
@en
P2093
Bhramdeo Bassit
Debra J Morrison
Hamid Band
Isabelle Gross
Jacqueline M Mason
Jonathan D Licht
Manjari Dimri
P2860
P304
P356
10.1091/MBC.E03-07-0503
P577
2004-03-05T00:00:00Z