Fluconazole resistance associated with drug efflux and increased transcription of a drug transporter gene, PDH1, in Candida glabrata
about
Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulenceSystematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genesTn7-based genome-wide random insertional mutagenesis of Candida glabrata.Chemosensitization of fluconazole resistance in Saccharomyces cerevisiae and pathogenic fungi by a D-octapeptide derivative.Functional genomic analysis of fluconazole susceptibility in the pathogenic yeast Candida glabrata: roles of calcium signaling and mitochondria.Efflux in fungi: la pièce de résistanceFungal PDR transporters: Phylogeny, topology, motifs and function.Mechanisms of azole resistance in clinical isolates of Candida glabrata collected during a hospital survey of antifungal resistance.Rapid acquisition of stable azole resistance by Candida glabrata isolates obtained before the clinical introduction of fluconazole.The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents.Role of ATP-binding-cassette transporter genes in high-frequency acquisition of resistance to azole antifungals in Candida glabrata.In vitro and in vivo effects of 14alpha-demethylase (ERG11) depletion in Candida glabrataMilbemycin A4 oxime as a probe of azole transport in Candida glabrataConservation of a portion of the S. cerevisiae Ure2p prion domain that interacts with the full-length protein.Candida glabrata PDR1, a transcriptional regulator of a pleiotropic drug resistance network, mediates azole resistance in clinical isolates and petite mutants.Loss of mitochondrial functions associated with azole resistance in Candida glabrata results in enhanced virulence in micePrion-forming ability of Ure2 of yeasts is not evolutionarily conserved.Azole resistance of Candida glabrata in a case of recurrent fungemiaMolecular mechanisms of itraconazole resistance in Candida dubliniensis.The [URE3] prion in Candida.Clotrimazole Drug Resistance in Candida glabrata Clinical Isolates Correlates with Increased Expression of the Drug:H(+) Antiporters CgAqr1, CgTpo1_1, CgTpo3, and CgQdr2.Antifungal resistance of Candida glabrata vaginal isolates and development of a quantitative reverse transcription-PCR-based azole susceptibility assay.Efflux-mediated antifungal drug resistance.Coordinate control of lipid composition and drug transport activities is required for normal multidrug resistance in fungi.Azole resistance in Candida glabrata: coordinate upregulation of multidrug transporters and evidence for a Pdr1-like transcription factor.Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species.Transcription factor CCG-8 as a new regulator in the adaptation to antifungal azole stress.Mechanism of increased fluconazole resistance in Candida glabrata during prophylaxis.Multidrug resistance in fungi: regulation of transporter-encoding gene expression.Typing of Candida glabrata in clinical isolates by comparative sequence analysis of the cytochrome c oxidase subunit 2 gene distinguishes two clusters of strains associated with geographical sequence polymorphisms.Phenotypic switching in Candida glabrata involves phase-specific regulation of the metallothionein gene MT-II and the newly discovered hemolysin gene HLP.Relationships between respiration and susceptibility to azole antifungals in Candida glabrata.Unexpected effects of azole transporter inhibitors on antifungal susceptibility in Candida glabrata and other pathogenic Candida species.Mechanisms of azole resistance in petite mutants of Candida glabrata.Interactions between copy number and expression level of genes involved in fluconazole resistance in Candida glabrataGenomewide expression profile analysis of the Candida glabrata Pdr1 regulon.Contributions of Aspergillus fumigatus ATP-binding cassette transporter proteins to drug resistance and virulence.Pathogenesis and Antifungal Drug Resistance of the Human Fungal Pathogen Candida glabrata.Azole Resistance Caused by Increased Drug Efflux in Candida glabrata Isolated from the Urinary Tract of a Dog with Diabetes Mellitus.Characterisation of an ABC transporter of a resistant Candida glabrata clinical isolate.
P2860
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P2860
Fluconazole resistance associated with drug efflux and increased transcription of a drug transporter gene, PDH1, in Candida glabrata
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Fluconazole resistance associa ...... ene, PDH1, in Candida glabrata
@ast
Fluconazole resistance associa ...... ene, PDH1, in Candida glabrata
@en
type
label
Fluconazole resistance associa ...... ene, PDH1, in Candida glabrata
@ast
Fluconazole resistance associa ...... ene, PDH1, in Candida glabrata
@en
prefLabel
Fluconazole resistance associa ...... ene, PDH1, in Candida glabrata
@ast
Fluconazole resistance associa ...... ene, PDH1, in Candida glabrata
@en
P2093
P2860
P1476
Fluconazole resistance associa ...... ene, PDH1, in Candida glabrata
@en
P2093
C Hitchcock
D J Falconer
H Miyazaki
J E Bennett
T Parkinson
Y Miyazaki
P2860
P304
P407
P577
1998-07-01T00:00:00Z