Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?
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Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturationLigand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1Sphingolipid signaling in metabolic disordersSli2 (Ypk1), a homologue of mammalian protein kinase SGK, is a downstream kinase in the sphingolipid-mediated signaling pathway of yeast.Pulmonary phosphatidic acid phosphatase and lipid phosphate phosphohydrolaseExtracellular mechanism through the Edg family of receptors might be responsible for sphingosine-1-phosphate-induced regulation of DNA synthesis and migration of rat aortic smooth-muscle cellsA novel function of sphingosine-1-phosphate to activate a non-selective cation channel in human endothelial cellsInvolvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neuronsInhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3G(i)-mediated Cas tyrosine phosphorylation in vascular endothelial cells stimulated with sphingosine 1-phosphate: possible involvement in cell motility enhancement in cooperation with Rho-mediated pathways.Sphingosine-1-phosphate elicits receptor-dependent calcium signaling in retinal amacrine cellsThe sphingosine 1-phosphate receptor, S1PR₁, plays a prominent but not exclusive role in enhancing the excitability of sensory neurons.Adipocyte lipolysis-stimulated interleukin-6 production requires sphingosine kinase 1 activity.Rac1 modification by an electrophilic 15-deoxy Δ(12,14)-prostaglandin J2 analog.Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expressionSteroidogenic factor-1 is a sphingolipid binding proteinThe role of sphingosine kinase 1/sphingosine-1-phosphate pathway in the myogenic tone of posterior cerebral arteries.VEGF induces S1P1 receptors in endothelial cells: Implications for cross-talk between sphingolipid and growth factor receptors.Sphingosine-1-phosphate: an emerging therapeutic target.Fluid shear stress modulates endothelial cell invasion into three-dimensional collagen matricesPathogenic angiogenesis in IBD and experimental colitis: new ideas and therapeutic avenues.Cytosolic phospholipase A2alpha activation induced by S1P is mediated by the S1P3 receptor in lung epithelial cells.Balance of S1P1 and S1P2 signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature.FTY720 Attenuates Angiotensin II-Induced Podocyte Damage via Inhibiting Inflammatory Cytokines.The interplay between bioactive sphingolipids and steroid hormones.The influences of metabotropic receptor activation on cellular signaling and synaptic function in amacrine cells.The role of sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) in regulation of osteoclastic and osteoblastic cells.Phospholipase D1 is threonine-phosphorylated in human-airway epithelial cells stimulated by sphingosine-1-phosphate by a mechanism involving Src tyrosine kinase and protein kinase Cdelta.Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes.Sphingosine-1-phosphate receptor subtype 2 signaling in endothelial senescence-associated functional impairments and inflammation.Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells.Sphingosine-1-phosphate rapidly increases cortisol biosynthesis and the expression of genes involved in cholesterol uptake and transport in H295R adrenocortical cellsFibronectin promotes calcium signaling by interferon-gamma in human neutrophils via G-protein and sphingosine kinase-dependent mechanisms.ACTH regulates steroidogenic gene expression and cortisol biosynthesis in the human adrenal cortex via sphingolipid metabolism.Lysophospholipids increase ICAM-1 expression in HUVEC through a Gi- and NF-kappaB-dependent mechanism.Sphingosine 1-phosphate induces Ca2+ transients and cytoskeletal rearrangement in C2C12 myoblastic cells.New drug delivery system for liver sinusoidal endothelial cells for ischemia-reperfusion injury.Sphingosine-1-phosphate and sphingosylphosphorylcholine constrict renal and mesenteric microvessels in vitro.Assessment of the role of sphingosine 1-phosphate and its receptors in high-density lipoprotein-induced stimulation of astroglial cell function.
P2860
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P2860
Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?
@ast
Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?
@en
type
label
Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?
@ast
Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?
@en
prefLabel
Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?
@ast
Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?
@en
P2093
P1476
Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger?
@en
P2093
P304
P356
10.1016/S0006-2952(99)00086-6
P407
P50
P577
1999-07-01T00:00:00Z